Search Results - "elder, robert"

Unique clinical challenges for the teenager with congenital heart disease by Pastor, Tony, Elder, Robert W.

“…Purpose of review On top of existing rites of passage, adolescents with congenital heart disease (CHD) face additional challenges as related to their…”
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Predicting Solute Diffusivity in Polymers Using Time–Temperature Superposition by Elder, Robert M., Saylor, David M.

“…We demonstrate a novel application of the time–temperature superposition (TTS) principle to predict solute diffusivity D in glassy polymers using atomistic…”
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Relations Between Dynamic Localization and Solute Diffusion in Polymers by Elder, Robert M, Saylor, David M

“…Various public health concerns can arise from the unintended leaching of additives and impurities from polymeric medical devices or food packaging, which is…”
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Impact of the new heart allocation policy on patients with restrictive, hypertrophic, or congenital cardiomyopathies by Chouairi, Fouad, Mullan, Clancy W, Sen, Sounok, Mori, Makoto, Fuery, Michael, Elder, Robert W, Lesse, Joshua, Norton, Kelsey, Clark, Katherine A, Miller, P Elliott, Mulligan, David, Formica, Richard, Rogers, Joseph G, Jacoby, Daniel, Maulion, Christopher, Anwer, Muhammad, Geirsson, Arnar, Desai, Nihar R, Ahmad, Tariq

“…Patients with restrictive or hypertrophic cardiomyopathy (RCM/HCM) and congenital heart disease (CHD) do not derive clinical benefit from inotropes and…”
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Understanding the Effect of Polylysine Architecture on DNA Binding Using Molecular Dynamics Simulations by Elder, Robert M., Emrick, Todd, Jayaraman, Arthi

“…Polycations with varying chemistries and architectures have been synthesized and used in DNA transfection. In this paper we connect poly-l-lysine (PLL)…”
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HIV-1 Protease in the Fission Yeast Schizosaccharomyces pombe by Benko, Zsigmond, Elder, Robert T, Li, Ge, Liang, Dong, Zhao, Richard Y

“…HIV-1 protease (PR) is an essential viral enzyme. Its primary function is to proteolyze the viral Gag-Pol polyprotein for production of viral enzymes and…”
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Stacking order dependent mechanical properties of graphene/MoS2 bilayer and trilayer heterostructures by Elder, Robert M., Neupane, Mahesh R., Chantawansri, Tanya L.

“…Transition metal dichalcogenides (TMDC) such as molybdenum disulfide (MoS2) are two-dimensional materials that show promise for flexible electronics and…”
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Effect of Hydrophobic and Hydrophilic Surfaces on the Stability of Double-Stranded DNA by Elder, Robert M, Pfaendtner, Jim, Jayaraman, Arthi

“…DNA hybridization is the foundation for numerous technologies like DNA origami and DNA sensing/microarrays. Using molecular simulations, enhanced-sampling…”
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Polymer-Interface-Tissue Model to Estimate Leachable Release from Medical Devices by Tanaka, Martin L, Saylor, David M, Elder, Robert M

“…The ability to predict clinically relevant exposure to potentially hazardous compounds that can leach from polymeric components can help reduce testing needed…”
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Hemodynamic Phenotype of the Failing Fontan in an Adult Population by Hebson, Camden L., MD, McCabe, Nancy M., BSN-PhD, Elder, Robert W., MD, Mahle, William T., MD, McConnell, Michael, MD, Kogon, Brian E., MD, Veledar, Emir, PhD, Jokhadar, Maan, MD, Vincent, Robert N., MD, Sahu, Anurag, MD, Book, Wendy M., MD

“…Fontan failure can occur even with normal systolic ventricular function and often in the context of significant liver disease. We hypothesized that Fontan…”
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Identifying Gender and Racial Bias in Pediatric Fellowship Letters of Recommendation: Do Word Choices Influence Interview Decisions? by Boolchandani, Henna, Chen, Laura, Elder, Robert W., Osborn, Rachel, Phatak, Uma P., Puthenpura, Vidya, Sheares, Beverley J., Tiyyagura, Gunjan, Amster, Leah, Lee, Seohyuk, Langhan, Melissa L.

“…To describe linguistic differences in letters of recommendation (LORs) for pediatric fellowship candidates based on applicant and letter writer demographics…”
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Identifying Nonaffine Softening Modes in Glassy Polymer Networks: A Pathway to Chemical Design by Elder, Robert M, Zaccone, Alessio, Sirk, Timothy W

“…Using molecular simulations and theory, we develop an explicit mapping of the contribution of molecular relaxation modes in glassy thermosets to the shear…”
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Sequence-Specific Recognition of Cancer Drug-DNA Adducts by HMGB1a Repair Protein by Elder, Robert M., Jayaraman, Arthi

“…The efficacy of cancer drugs such as cisplatin (Cp) and oxaliplatin (Ox), which covalently bind to DNA to form drug-DNA adducts, is linked to their recognition…”
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Molecular Simulations of Polycation–DNA Binding Exploring the Effect of Peptide Chemistry and Sequence in Nuclear Localization Sequence Based Polycations by Elder, Robert M, Jayaraman, Arthi

“…Gene therapy relies on the delivery of DNA into cells, and polycations are one class of vectors enabling efficient DNA delivery. Nuclear localization sequences…”
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A window into portal hemodynamics in adult fontan patients? by Simmons, M. Abigail, Revzin, Margarita, To, Uyen, Liapakis, Annmarie, Fahey, John, Elder, Robert W.

“…Fontan circulation alters portal venous hemodynamics, causing chronic passive hepatic congestion and fibrosis. This congestion increases liver stiffness (LS)…”
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Single ventricle palliation in congenitally corrected transposition of the great arteries: An international multicenter study by Kalfa, David M., Buratto, Edward, Bacha, Emile A., Belli, Emre, Barron, David J., Ly, Mohamed, Nield, Lynne, McLeod, Christopher, Khairy, Paul, Babu-Narayan, Sonya V., Kowalik, Ewa, Elder, Robert W., Baruteau, Alban-Elouen

“…Single ventricle palliation may be performed in patients with congenitally corrected transposition of the great arteries due to hypoplasia of 1 ventricle or…”
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Features of portal hypertension are associated with major adverse events in Fontan patients: The VAST study by Elder, Robert W, McCabe, Nancy M, Hebson, Camden, Veledar, Emir, Romero, Rene, Ford, Ryan M, Mahle, William T, Kogon, Brian E, Sahu, Anurag, Jokhadar, Maan, McConnell, Michael E, Book, Wendy M

“…Abstract Background Chronic congestive hepatopathy is known to cause hepatic fibrosis and portal hypertension in patients post-Fontan operation for single…”
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More on Hepatocellular Carcinoma after the Fontan Procedure by Elder, Robert W, Parekh, Samir, Book, Wendy M

“…To the Editor: The letter by Asrani et al. (May 2 issue) 1 reports cases of hepatocellular carcinoma in patients who have undergone Fontan palliation for…”
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Leveraging Extraction Testing to Predict Patient Exposure to Polymeric Medical Device Leachables Using Physics-based Models by Turner, Paul, Elder, Robert M, Nahan, Keaton, Talley, Anne, Shah, Saloni, Duncan, Timothy V, Sussman, Eric M, Saylor, David M

“…Toxicological risk assessment approaches are increasingly being used in lieu of animal testing to address toxicological concerns associated with release of…”
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Coarse-Grained Simulation Studies of Effects of Polycation Architecture on Structure of the Polycation and Polycation–Polyanion Complexes by Elder, Robert M, Jayaraman, Arthi

“…Polycations are a promising class of nonviral DNA delivery agents that bind to negatively charged DNA and transfect the DNA into target cells. The architecture…”
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