Search Results - "duBell, W H"

K(+) currents responsible for repolarization in mouse ventricle and their modulation by FK-506 and rapamycin by DuBell, W H, Lederer, W J, Rogers, T B

“…Modulation of mouse ventricular action potentials and K(+) currents was examined using the whole cell patch-clamp technique. The composite mouse ventricular…”
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Cytosolic calcium and myofilaments in single rat cardiac myocytes achieve a dynamic equilibrium during twitch relaxation by Spurgeon, H A, duBell, W H, Stern, M D, Sollott, S J, Ziman, B D, Silverman, H S, Capogrossi, M C, Talo, A, Lakatta, E G

“…1. Single isolated rat cardiac myocytes were loaded with either the pentapotassium salt form or the acetoxymethyl ester (AM) form of the calcium-sensitive…”
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Independent inhibition of calcineurin and K+ currents by the immunosuppressant FK-506 in rat ventricle by duBell, W H, Gaa, S T, Lederer, W J, Rogers, T B

“…FK-506 increases the cytosolic Ca2+ concentration transient in rat ventricular myocytes by prolonging the action potential through inhibition of the K+…”
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Ankyrin-B mutation causes type 4 long-QT cardiac arrhythmia and sudden cardiac death by Bennett, Vann, Mohler, Peter J, Schott, Jean-Jacques, Gramolini, Anthony O, Dilly, Keith W, Guatimosim, Silvia, duBell, William H, Song, Long-Sheng, Haurogné, Karine, Kyndt, Florence, Ali, Mervat E, Rogers, Terry B, Lederer, W. J, Escande, Denis, Marec, Herve Le

“…Mutations in ion channels involved in the generation and termination of action potentials constitute a family of molecular defects that underlie fatal cardiac…”
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Dynamic modulation of excitation-contraction coupling by protein phosphatases in rat ventricular myocytes by duBell, W H, Lederer, W J, Rogers, T B

“…1. The effects of the serine/threonine protein phosphatases (PP) type 1 and 2A on L-type Ca2+ current (ICa) and the intracellular [Ca2+]i transient were…”
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The cytosolic calcium transient modulates the action potential of rat ventricular myocytes by duBell, W H, Boyett, M R, Spurgeon, H A, Talo, A, Stern, M D, Lakatta, E G

“…1. The modulation of the action potential by the cytosolic Ca2+ (Cai2+) transient was studied in single isolated rat ventricular myocytes loaded with the…”
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Repletion of sarcoplasmic reticulum Ca after ryanodine in rat ventricular myocytes by duBell, W H, Lewartowski, B, Spurgeon, H A, Silverman, H S, Lakatta, E G

“…The ryanodine (R)-induced loss of sarcoplasmic reticulum (SR) Ca2+ and the abilities of the SR to accumulate Ca2+ and participate in contractile activation…”
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Initial contractile response of isolated rat heart cells to halothane, enflurane, and isoflurane by WHEELER, D. M, RICE, R. T, DUBELL, W. H, SPURGEON, H. A

“…In several beating cardiac muscle preparations, a short-lived increase in twitch tension or amplitude has been observed when they were exposed abruptly to…”
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Rest decay of calcium transients and contractility in feline ventricular myocytes by DuBell, W H, Houser, S R

“…To define the respective contributions of sarcoplasmic reticulum Ca2+ release and action potential-dependent Ca2+ influx to the activator Ca2+, rest decay of…”
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Effect of the immunosupressant FK506 on excitation-contraction coupling and outward K+ currents in rat ventricular myocytes by DuBell, William H., Wright, Pamela A., Lederer, W. J., Rogers, Terry B.

“…1. We examined the effects of the immunosupressant drug FK506 on excitation-contraction coupling in isolated rat ventricular myocytes. [Ca2+]i transients were…”
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Voltage and beat dependence of Ca2+ transient in feline ventricular myocytes by duBell, W H, Houser, S R

“…The positive contractile staircase after a period of rest is attributable to a positive staircase in the magnitude of the Ca2+ transient. The present study…”
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A comparison of cytosolic free Ca2+ in resting feline and rat ventricular myocytes by duBell, W H, Houser, S R

“…The Ca2+-sensitive dye quin-2 was used to measure the cytosolic free Ca2+ (Cai2+) in suspensions of ventricular myocytes isolated from cat and rat ventricles…”
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Protein phosphatase 1 and an opposing protein kinase regulate steady-state L-type Ca super(2+) current in mouse cardiac myocytes by duBell, W H, Rogers, T B

“…Studies have suggested that integration of kinase and phosphatase activities maintains the steady-state L-type Ca super(2+) current in ventricular myocytes, a…”
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Protein phosphatase 1 and an opposing protein kinase regulate steady-state L-type Ca2+ current in mouse cardiac myocytes by DuBell, William H., Rogers, Terry B.

“…Studies have suggested that integration of kinase and phosphatase activities maintains the steady-state L-type Ca 2+ current in ventricular myocytes, a balance…”
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Effects of PP1/PP2A inhibitor calyculin A on the E-C coupling cascade in murine ventricular myocytes by duBell, William H, Gigena, Marisa S, Guatimosim, Silvia, Long, Xilin, Lederer, W J, Rogers, Terry B

“…Calyculin A was used to examine the importance of phosphatases in the modulation of cardiac contractile magnitude in the absence of any neural or humoral…”
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The cytosolic calcium transient modulates the action potential of rat ventricular myocyte by DUBELL, W. H, BOYETT, M. R, SPURGEON, H. A, TALO, A, STERN, M. D, LAKATTA, E. G

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