Search Results - "du Preez, Karen"
-
1
Child contact management in high tuberculosis burden countries: A mixed-methods systematic review
Published in PloS one (01-08-2017)“…Tuberculosis (TB) remains a leading cause of morbidity and mortality worldwide. Considering the World Health Organization recommendation to implement child…”
Get full text
Journal Article -
2
Excellent Treatment Outcomes in Children Treated for Tuberculosis Under Routine Operational Conditions in Cape Town, South Africa
Published in Clinical infectious diseases (01-11-2017)“…Tuberculosis (TB) remains a leading cause of death in children globally. It is recognized that human immunodeficiency virus (HIV) infection increases the risk…”
Get full text
Journal Article -
3
Tuberculosis prevention in children: a prospective community-based study in South Africa
Published in The European respiratory journal (01-04-2021)“…Tuberculosis (TB) preventive therapy reduces TB risk in children. However, the effectiveness of TB preventive therapy in children living in high TB burden…”
Get full text
Journal Article -
4
Early mortality in tuberculosis patients initially lost to follow up following diagnosis in provincial hospitals and primary health care facilities in Western Cape, South Africa
Published in PloS one (14-06-2021)“…In South Africa, low tuberculosis (TB) treatment coverage and high TB case fatality remain important challenges. Following TB diagnosis, patients must link…”
Get full text
Journal Article -
5
Prevalence of Respiratory Health Symptoms among Landfill Waste Recyclers in the City of Johannesburg, South Africa
Published in International journal of environmental research and public health (04-11-2019)“…In developing countries, waste sorting and recycling have become a source of income for poorer communities. However, it can potentially pose significant health…”
Get full text
Journal Article -
6
The Magnitude of Interferon Gamma Release Assay Responses in Children With Household Tuberculosis Contact Is Associated With Tuberculosis Exposure and Disease Status
Published in The Pediatric infectious disease journal (01-08-2021)“…The clinical utility of the magnitude of interferon gamma (IFNγ) in response to mycobacterial antigens is unknown. We assessed the association between…”
Get full text
Journal Article -
7
Tuberculous Meningitis in Children: Reducing the Burden of Death and Disability
Published in Pathogens (Basel) (30-12-2021)“…Tuberculous meningitis disproportionately affects young children. As the most devastating form of tuberculosis, it is associated with unacceptably high rates…”
Get full text
Journal Article -
8
Tuberculosis in persons with sudden unexpected death, in Cape Town, South Africa
Published in International journal of infectious diseases (01-04-2021)“…•There is a high prevalence of TB among sudden unexpected deaths.•Most TB detected at post-mortem was undiagnosed before death.•In a high burden TB setting,…”
Get full text
Journal Article -
9
Reducing Initial Loss to Follow-up Among People With Bacteriologically Confirmed Tuberculosis: LINKEDin, a Quasi-experimental Study in South Africa
Published in Open forum infectious diseases (2024)“…Every person diagnosed with tuberculosis (TB) needs to initiate treatment. The World Health Organization estimated that 61% of people who developed TB in 2021…”
Get full text
Journal Article -
10
Complementary surveillance strategies are needed to better characterise the epidemiology, care pathways and treatment outcomes of tuberculosis in children
Published in BMC public health (23-03-2018)“…Tuberculosis (TB) in young and HIV-infected children is frequently diagnosed at hospital level. In settings where general hospitals do not function as TB…”
Get full text
Journal Article -
11
Tuberculous Meningitis in Children: A Forgotten Public Health Emergency
Published in Frontiers in neurology (17-03-2022)“…Tuberculous meningitis (TBM) remains a major cause of morbidity and mortality in children with tuberculosis (TB), yet there are currently no estimates of the…”
Get full text
Journal Article -
12
A systematic review of risk factors for mortality among tuberculosis patients in South Africa
Published in Systematic reviews (23-02-2023)“…Tuberculosis (TB)-associated mortality in South Africa remains high. This review aimed to systematically assess risk factors associated with death during TB…”
Get full text
Journal Article -
13
HIV and TB Workplace Program for Street Vendors: A Situational Analysis
Published in New solutions (01-05-2022)“…In South Africa, 15 percent of informal economy workers are street vendors. The organization of occupational health services in the country is fragmented and…”
Get full text
Journal Article -
14
Navigating complex care pathways-healthcare workers' perspectives on health system barriers for children with tuberculous meningitis in Cape Town, South Africa
Published in PLOS global public health (2024)“…Tuberculous meningitis (TBM) occurs when tuberculosis (TB) bacilli disseminate and seed into the meninges, triggering a severe inflammatory response that often…”
Get full text
Journal Article -
15
The impact of drug resistance on the risk of tuberculosis infection and disease in child household contacts: a cross sectional study
Published in BMC infectious diseases (29-08-2017)“…The relative fitness of organisms causing drug-susceptible (DS) and multidrug-resistant (MDR) tuberculosis (TB) is unclear. We compared the risk of TB…”
Get full text
Journal Article -
16
Does an isoniazid prophylaxis register improve tuberculosis contact management in South African children?
Published in PloS one (10-12-2013)“…We compared the change in child household contact management of pulmonary tuberculosis (TB) cases before and after the implementation of an isoniazid…”
Get full text
Journal Article -
17
Correction to: The impact of drug resistance on the risk of tuberculosis infection and disease in child household contacts: a cross sectional study
Published in BMC infectious diseases (07-11-2017)“…After publication of the original article [1] the authors noted that the following errors had occurred…”
Get full text
Journal Article -
18
205 A comparison of amended occupational exposure limits (maximum limits) promulgated in South Africa with limit values from other countries
Published in Annals of work exposures and health (27-06-2024)“…Abstract South African occupational exposure limits for hazardous chemical agents were revised in 2021 and introduced some limit values that were lowered by up…”
Get full text
Journal Article -
19
Isoniazid Preventive Therapy in HIV-Infected Pregnant and Postpartum Women
Published in The New England journal of medicine (03-10-2019)“…In this report, the timing of isoniazid therapy to prevent tuberculosis in pregnant women with HIV infection was assessed. Intrapartum isoniazid treatment…”
Get full text
Journal Article -
20
Correction: Early mortality in tuberculosis patients initially lost to follow up following diagnosis in provincial hospitals and primary health care facilities in Western Cape, South Africa
Published in PloS one (14-03-2024)“…[This corrects the article DOI: 10.1371/journal.pone.0252084.]…”
Get full text
Journal Article