Search Results - "dos Santos Lopes, Fernanda Degobbi Tenorio Quirino"
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iNOS Inhibition Reduces Lung Mechanical Alterations and Remodeling Induced by Particulate Matter in Mice
Published in Pulmonary medicine (01-01-2019)“…Background. The epidemiologic association between pulmonary exposure to ambient particulate matter (PM) and acute lung damage is well known. However, the…”
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Chronic exposure to diesel particles worsened emphysema and increased M2-like phenotype macrophages in a PPE-induced model
Published in PloS one (31-01-2020)“…Chronic exposure to ambient levels of air pollution induces respiratory illness exacerbation by increasing inflammatory responses and apoptotic cells in…”
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3
N-acetylcysteine prevents pulmonary edema and acute kidney injury in rats with sepsis submitted to mechanical ventilation
Published in American journal of physiology. Lung cellular and molecular physiology (01-04-2012)“…Sepsis is a common cause of acute kidney injury (AKI) and acute lung injury. Oxidative stress plays as important role in such injury. The aim of this study was…”
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4
Microenvironmental stimuli induce different macrophage polarizations in experimental models of emphysema
Published in Biology open (2019)“…Macrophages play a pivotal role in the development of emphysema and depending on the microenvironment stimuli can be polarized into M1- or M2-like macrophage…”
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Th17/Treg imbalance in COPD progression: A temporal analysis using a CS-induced model
Published in PloS one (10-01-2019)“…The imbalance between pro- and anti-inflammatory immune responses plays a pivotal role in chronic obstructive pulmonary disease (COPD) development and…”
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Low-dose chlorine exposure impairs lung function, inflammation and oxidative stress in mice
Published in Life sciences (1973) (15-02-2021)“…To explore the different consequences of acute and chronic exposure to chlorine gas (Cl2) on the functional and histological parameters of health mice…”
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Respiratory mechanics do not always mirror pulmonary histological changes in emphysema
Published in Clinics (São Paulo, Brazil) (01-01-2011)“…: To verify the accordance of functional and morphometric parameters during the development of emphysema. : BALB/c mice received a nasal drop of either papain…”
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Increased bone resorption by long-term cigarette smoke exposure in animal model
Published in Heliyon (01-12-2021)“…Clinical and experimental studies have been attesting the deleterious effects of smoking mainly due to the stimulation of osteoclastogenesis and inhibition of…”
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A new experimental model of cigarette smoke-induced emphysema in Wistar rats
Published in Jornal brasileiro de pneumologia (01-01-2014)“…To describe a new murine model of cigarette smoke-induced emphysema. Twenty-four male Wistar rats were divided into two groups: the cigarette smoke group,…”
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Th17/Treg Imbalance in Chronic Obstructive Pulmonary Disease: Clinical and Experimental Evidence
Published in Frontiers in immunology (09-12-2021)“…The imbalance between pro- and anti-inflammatory immune responses mediated by Th17 and Treg cells is deeply involved in the development and progression of…”
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11
Smoking induces increased apoptosis in osteoblasts: changes in bone matrix organic components
Published in Scientific reports (28-04-2023)“…Clinical studies demonstrate the impact of smoking on bone tissue fragility and higher incidence of fractures. However, it is not totally understood which…”
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Modulating asthma-COPD overlap responses with IL-17 inhibition
Published in Frontiers in immunology (27-10-2023)“…IL-17 is a modulator of the inflammatory response and is implicated in lung remodeling in both asthma and chronic obstructive pulmonary disease (COPD). Well as…”
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13
Different Phenotypes in Asthma: Clinical Findings and Experimental Animal Models
Published in Clinical reviews in allergy & immunology (01-02-2022)“…Asthma is a respiratory allergic disease presenting a high prevalence worldwide, and it is responsible for several complications throughout life, including…”
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Type V collagen-induced nasal tolerance prevents lung damage in an experimental model: new evidence of autoimmunity to collagen V in COPD
Published in Frontiers in immunology (05-09-2024)“…Chronic obstructive pulmonary disease (COPD) has been linked to immune responses to lung-associated self-antigens. Exposure to cigarette smoke (CS), the main…”
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Lung Mechanics Over the Century: From Bench to Bedside and Back to Bench
Published in Frontiers in physiology (13-07-2022)“…Lung physiology research advanced significantly over the last 100 years. Respiratory mechanics applied to animal models of lung disease extended the knowledge…”
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Diesel exhaust exposure intensifies inflammatory and structural changes associated with lung aging in mice
Published in Ecotoxicology and environmental safety (15-04-2019)“…Life expectancy is increasing worldwide. Lung aging is a process marked by changes in multiple morphological, physiological and age-related biomarkers (e.g.,…”
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Effect of VAChT reduction on lung alterations induced by exposure to iron particles in an asthma model
Published in Journal of inflammation (London, England) (03-07-2024)“…Pollution harms the health of people with asthma. The effect of the anti-inflammatory cholinergic pathway in chronic allergic inflammation associated to…”
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Correction: Effect of VAChT reduction on lung alterations induced by exposure to iron particles in an asthma model
Published in Journal of inflammation (London, England) (30-07-2024)Get full text
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Bronchial Vascular Remodeling Is Attenuated by Anti-IL-17 in Asthmatic Responses Exacerbated by LPS
Published in Frontiers in pharmacology (04-09-2020)“…Although the major alterations associated with asthma are related to the airways, there is also evidence of the importance of peribronchial vascular…”
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Investigating the Effects of a New Peptide, Derived from the Enterolobium contortisiliquum Proteinase Inhibitor (EcTI), on Inflammation, Remodeling, and Oxidative Stress in an Experimental Mouse Model of Asthma–Chronic Obstructive Pulmonary Disease Overlap (ACO)
Published in International journal of molecular sciences (01-10-2023)“…The synthesized peptide derived from Enterolobium contortisiliquum (pep3-EcTI) has been associated with potent anti-inflammatory and antioxidant effects, and…”
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