Search Results - "dos Santos Jaques, Hellen"
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Occupational exposure to pesticides dysregulates systemic Th1/Th2/Th17 cytokines and correlates with poor clinical outcomes in breast cancer patients
Published in Frontiers in immunology (24-10-2023)“…Pesticides are compounds known to cause immunetoxicity in exposed individuals, which have a potential to substantially modify the prognosis of pathologies…”
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Brief research report pesticide occupational exposure leads to significant inflammatory changes in normal mammary breast tissue
Published in Frontiers in public health (14-09-2023)“…Studies have documented the high occurrence of several tumors, including female breast cancer, in populations occupationally exposed to pesticides worldwide…”
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Occupational Exposure to Pesticides Affects Pivotal Immunologic Anti-Tumor Responses in Breast Cancer Women from the Intermediate Risk of Recurrence and Death
Published in Cancers (23-10-2022)“…Breast cancer risk stratification is a strategy based using on clinical parameters to predict patients’ risk of recurrence or death, categorized as low,…”
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Pesticide exposure and oxidative stress generation are linked to poor prognosis outcomes in breast cancer women carrying the allelic variant rs7438135 in the UGT2B7 gene
Published in Journal of biochemical and molecular toxicology (01-11-2024)“…Pesticide exposure is a risk factor for the development of several diseases, including breast cancer (BC). The enzyme UGT2B7 participate in detoxification of…”
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Somatic DNA Damage Response and Homologous Repair Gene Alterations and Its Association With Tumor Variant Burden in Breast Cancer Patients With Occupational Exposure to Pesticides
Published in Frontiers in oncology (08-07-2022)“…Homologous recombination is a crucial pathway that is specialized in repairing double-strand breaks; thus, alterations in genes of this pathway may lead to…”
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Excess body weight significantly affects systemic and tumor inflammatory status and correlates to poor prognosis parameters in patients with breast cancer
Published in Current research in immunology (01-01-2023)“…Obesity is a pro-inflammatory disease critical for developing breast cancer (BC), which impacts the profiles of systemic inflammatory mediators and…”
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Clinicopathological correlation between trophic-adipose levels and poor prognosis outcomes in Brazilian women diagnosed with breast cancer
Published in Brazilian Journal of Oncology (01-10-2021)“…Objective: To describe the clinicopathological profile of breast cancer patients and association with excess body weight. Methods: This was a descriptive…”
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