Search Results - "dos Santos Borges, Rosivaldo"
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Molecular interactions of the Omicron, Kappa, and Delta SARS-CoV-2 spike proteins with quantum dots of graphene oxide
Published in Journal of molecular modeling (01-07-2024)“…Context The Omicron, Kappa, and Delta variants are different strains of the SARS-CoV-2 virus. Graphene oxide quantum dots (GOQDs) represent a burgeoning class…”
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An In Silico Study of the Antioxidant Ability for Two Caffeine Analogs Using Molecular Docking and Quantum Chemical Methods
Published in Molecules (Basel, Switzerland) (29-10-2018)“…The antioxidant activity of molecules constitutes an important factor for the regulation of redox homeostasis and reduction of the oxidative stress. Cells…”
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Anti-Inflammatory Potential of 1-Nitro-2-Phenylethylene
Published in Molecules (Basel, Switzerland) (15-11-2017)“…Inflammation is a reaction of the host to infectious or sterile stimuli and has the physiological purpose of restoring tissue homeostasis. However,…”
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Sugar moiety has a synergistic effect on hydroxylated xanthone for better antioxidant activity of mangiferin
Published in Medicinal chemistry research (01-04-2018)“…The structure–antioxidant relationship of mangiferin was elucidated by means of quantum chemistry calculations. The density functional theory level of theory…”
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Euterpe oleracea fruit (Açai)-enriched diet suppresses the development of experimental cerebral malaria induced by Plasmodium berghei (ANKA) infection
Published in BMC complementary and alternative medicine (11-01-2022)“…Cerebral malaria is one of the most severe complications attributed to protozoal infection by Plasmodium falciparum, gaining prominence in children mortality…”
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Mechanisms underlying the vasorelaxant effect of trans-4-methoxy-β-nitrostyrene in the rat mesenteric resistance arteries
Published in European journal of pharmacology (15-06-2019)“…Mechanisms underlying the vasorelaxant effects of the synthetic nitro compound, trans-4-methoxy-β-nitrostyrene (T4MN) were studied in isolated small resistance…”
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Experimental and theoretical approaches for the development of 4H-Chromene derivatives as inhibitors of tyrosinase
Published in Molecular simulation (13-06-2021)“…Tyrosinase (TYR) is a key enzyme that catalyzes the synthesis of melanin in plants, microorganisms and mammalian cells. Kojic acid (KA) is a well-known TYR…”
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New nanocarried phenobarbital formulation: Maintains better control of pentylenetetrazole-Induced seizures
Published in Biotechnology reports (Amsterdam, Netherlands) (01-12-2020)“…•For the first time, phenobarbital was intercalated in the layered double hydroxide.•This study evaluated the slow release efficacy of intercalated…”
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Antioxidant factors, nitric oxide levels, and cellular damage in leprosy patients
Published in Revista da Sociedade Brasileira de Medicina Tropical (01-09-2013)“…The immune response caused by Mycobacterium leprae is a risk factor for the development of oxidative stress (OS) in leprosy patients. This study aimed to…”
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Dihydroflavonols from the leaves of Derris urucu (Leguminosae): structural elucidation and DPPH radical-scavenging activity
Published in Journal of the Brazilian Chemical Society (2009)“…Derris urucu is an Amazonian plant with insecticide and ichthyotoxic properties. Studies with this species show the presence of flavonoids, mainly rotenoids,…”
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Interactions between carbon nanotubes and external structures of SARS-CoV-2 using molecular docking and molecular dynamics
Published in Journal of molecular structure (15-08-2023)“…•Thisresearch that there is a good chance of a relationship between these anchoring results and the effectiveness of Mycobacterium tuberculosis treatment.•The…”
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New derivative of trans-dehydrocrotonin isolated from Croton cajucara shows reduced cytotoxic and genotoxic effects in hepatocellular carcinoma (HepG2) cell line
Published in Toxicon (Oxford) (01-12-2022)“…The Croton cajucara (Euphorbiales, Euphorbiaceae) plant occurs widely in the Amazon region, where its leaves and stem bark are consumed by the population to…”
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Stimulation of pulmonary vagal C-fibers by trans-4-methyl-β-nitrostyrene induces bradycardiac and depressor reflex in rats: Role of vanilloid TRPV1 receptors
Published in European journal of pharmacology (15-04-2019)“…Previously, we showed that the synthetic nitroderivative trans-4-methyl-β-nitrostyrene (T4MeN) induced vasorelaxant effects in rat isolated aortic rings. Here,…”
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Theoretical and practical study of the cefoxitin‐Escherichia coli PBP5 complex interaction by molecular dynamics to obtain computational prototype of antimicrobial susceptibility to Gram negative bacteria
Published in Chemical biology & drug design (01-10-2020)“…The penicillin‐binding proteins (PBPs) are important biological target for new antibacterial drugs development. This study focused on molecular interaction…”
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Trans-4-methoxy-β-nitrostyrene relaxes rat thoracic aorta through a sGC-dependent pathway
Published in European journal of pharmacology (15-07-2017)“…1-Nitro-2-phenylethene (NPe) induces a more potent vasorelaxant effect in rat aorta than its structural analog 1-nitro-2-phenylethane, but mediated through a…”
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Diet enriched with the Amazon fruit açaí (Euterpe oleracea) prevents electrophysiological deficits and oxidative stress induced by methyl-mercury in the rat retina
Published in Nutritional neuroscience (28-05-2017)“…Background: The protective effect of a diet supplemented by the Amazonian fruit Euterpe oleracea (EO) against methylmercury (MeHg) toxicity in rat retina was…”
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Euterpe oleracea fruit infection
Published in BMC complementary medicine and therapies (11-01-2022)“…Background Cerebral malaria is one of the most severe complications attributed to protozoal infection by Plasmodium falciparum, gaining prominence in children…”
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