Search Results - "dos Santos, Keriolaine Lima"
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Novel 4-quinoline-thiosemicarbazone derivatives: Synthesis, antiproliferative activity, in vitro and in silico biomacromolecule interaction studies and topoisomerase inhibition
Published in European journal of medicinal chemistry (15-11-2019)“…Twelve 2-(quinolin-4-ylmethylene) hydrazinecarbothioamide derivatives were synthetized and their biological properties were investigated, among which, the…”
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Albumin roles in developing anticancer compounds
Published in Medicinal chemistry research (01-08-2021)“…Albumin is an abundant protein in nature with several biological functions. In the human body, both in health and in illness, its transport function is…”
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Preliminary evaluation of the interaction with Albumin/DNA and in vitro evaluation of the antioxidant properties promoted by thiosemicarbazones and thiazole compounds
Published in Scientific electronic archives (30-04-2024)“…Thiosemicarbazones and thiazoles are known for their diverse biological activities. This study introduced two series of molecules,…”
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COVID-19 therapy: What weapons do we bring into battle?
Published in Bioorganic & medicinal chemistry (01-12-2020)“…[Display omitted] Urgent treatments, in any modality, to fight SARS-CoV-2 infections are desired by society in general, by health professionals, by…”
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Interaction study with DNA/HSA, anti-topoisomerase IIα, cytotoxicity and in vitro antiproliferative evaluations and molecular docking of indole-thiosemicarbazone compounds
Published in International journal of biological macromolecules (15-04-2023)“…In this work we will discuss the antiproliferative evaluation and the possible mechanisms of action of indole-thiosemicarbazone compounds LTs with…”
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