Search Results - "dos Santos, Danubia Bonfanti"
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Ascorbic acid treatment, similarly to fluoxetine, reverses depressive-like behavior and brain oxidative damage induced by chronic unpredictable stress
Published in Journal of psychiatric research (01-03-2012)“…Abstract Reactive oxygen species (ROS) have been shown to play a role in the pathophysiology of depression. Taking into account that experimental chronic…”
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Lipopolysaccharide-Induced Striatal Nitrosative Stress and Impaired Social Recognition Memory Are Not Magnified by Paraquat Coexposure
Published in Neurochemical research (01-03-2018)“…Systemic inflammation triggered by lipopolysaccharide (LPS) administration disrupts blood–brain barrier (BBB) homeostasis in animal models. This event leads to…”
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Diphenyl diselenide supplementation reduces biochemical alterations associated with oxidative stress in rats fed with fructose and hydrochlorothiazide
Published in Chemico-biological interactions (25-08-2013)“…•Treatment with Hydrochlorothiazide (HCTZ) altered both glycemic and lipid profile.•High fructose diet (HFD) exaggerates metabolic end points of biochemical…”
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Long-term and low-dose malathion exposure causes cognitive impairment in adult mice: evidence of hippocampal mitochondrial dysfunction, astrogliosis and apoptotic events
Published in Archives of toxicology (01-03-2016)“…The organophosphorus (OP) pesticide malathion is a neurotoxic compound whose acute toxicity is primarily caused by the inhibition of acetylcholinesterase…”
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In vitro Reactivating Effects of Standard and Newly Developed Oximes on Malaoxon‐Inhibited Mouse Brain Acetylcholinesterase
Published in Basic & clinical pharmacology & toxicology (01-09-2010)“…: Malathion is an organophosphate (OP) pesticide whose toxicity depends on its bioactivation to malaoxon. Human malathion poisoning has been treated with…”
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Protective Effects of Ascorbic Acid on Behavior and Oxidative Status of Restraint-Stressed Mice
Published in Journal of molecular neuroscience (01-01-2013)“…Studies have demonstrated an association between stressful conditions and the onset of clinical depression. Considering the antidepressant-like properties of…”
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Increased susceptibility to amyloid-β-induced neurotoxicity in mice lacking the low-density lipoprotein receptor
Published in Journal of Alzheimer's disease (01-01-2014)“…Familial hypercholesterolemia is caused by inherited genetic abnormalities that directly or indirectly affect the function of the low-density lipoprotein (LDL)…”
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Cytotoxicity and Genotoxicity Evaluation of Organochalcogens in Human Leucocytes: A Comparative Study between Ebselen, Diphenyl Diselenide, and Diphenyl Ditelluride
Published in BioMed research international (01-01-2013)“…Organochalcogens, particularly ebselen, have been used in experimental and clinical trials with borderline efficacy. (PhSe)2 and (PhTe)2 are the simplest of…”
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Effects of K074 and pralidoxime on antioxidant and acetylcholinesterase response in malathion-poisoned mice
Published in Neurotoxicology (Park Forest South) (01-12-2011)“…► The oximes pralidoxime and K074 were administered 6 h after the malathion exposure. ► Malathion decreased the cortico-cerebral, hippocampal and blood AChE…”
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Modulation of Brain Glutathione Reductase and Peroxiredoxin 2 by α-Tocopheryl Phosphate
Published in Cellular and molecular neurobiology (01-08-2016)“…α-Tocopheryl phosphate (αTP) is a phosphorylated form of α-tocopherol. Since it is phosphorylated in the hydroxyl group that is essential for the antioxidant…”
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