Antifungal Activity of Coumarin Mammeisin Isolated from Species of the Kielmeyera Genre (Family: Clusiaceae or Guttiferae)

Coumarin mammeisin isolated from Kielmeyera elata was evaluated for its toxicity and antifungal activities. The toxicity of mammeisin was investigated by utilizing the Artemia salina methodology to determine its LD50 value. The minimum inhibitory concentration (MIC) of fungi Candida sp. was assessed...

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Bibliographic Details
Published in:	Journal of chemistry Vol. 2015; no. 2015; pp. 1 - 4
Main Authors:	Nagem, Tanus J., do Leonel Neto, Arman, Hamoy, Moisés, Taylor, Jason G., de Oliveira, Tânia T., Marcondes, Helcio Cassemiro, de Mello, Vanessa Joia
Format:	Journal Article
Language:	English
Published:	Cairo, Egypt Hindawi Publishing Corporation 01-01-2015 John Wiley & Sons, Inc Hindawi Limited
Subjects:	Chemical properties Coumarins Identification and classification
Online Access:	Get full text
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Summary:	Coumarin mammeisin isolated from Kielmeyera elata was evaluated for its toxicity and antifungal activities. The toxicity of mammeisin was investigated by utilizing the Artemia salina methodology to determine its LD50 value. The minimum inhibitory concentration (MIC) of fungi Candida sp. was assessed for mammeisin, presenting equivalent activity to ketoconazole but displaying better results than fluconazole.
ISSN:	2090-9063 2090-9071
DOI:	10.1155/2015/241243