Search Results - "di Tommaso, Anne"

Engineering venom's toxin-neutralizing antibody fragments and its therapeutic potential by Alvarenga, Larissa M, Zahid, Muhammad, di Tommaso, Anne, Juste, Matthieu O, Aubrey, Nicolas, Billiald, Philippe, Muzard, Julien

“…Serum therapy remains the only specific treatment against envenoming, but anti-venoms are still prepared by fragmentation of polyclonal antibodies isolated…”
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Exploration and Modulation of Antibody Fragment Biophysical Properties by Replacing the Framework Region Sequences by Cnudde, Thomas, Lakhrif, Zineb, Bourgoin, Justine, Boursin, Fanny, Horiot, Catherine, Henriquet, Corinne, di Tommaso, Anne, Juste, Matthieu Olivier, Jiacomini, Isabella Gizzi, Dimier-Poisson, Isabelle, Pugnière, Martine, Mévélec, Marie-Nöelle, Aubrey, Nicolas

“…In order to increase the successful development of recombinant antibodies and fragments, it seems fundamental to enhance their expression and/or biophysical…”
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Engineering and Functional Evaluation of Neutralizing Antibody Fragments Against Congenital Toxoplasmosis by di Tommaso, Anne, Juste, Matthieu O, Lakhrif, Zineb, Mévélec, Marie-Noëlle, Borowczyk, Coraline, Hammeni, Pierre, Désoubeaux, Guillaume, Van Langendonck, Nathalie, Debierre-Grockiego, Françoise, Aubrey, Nicolas, Dimier-Poisson, Isabelle

“…Abstract Maternal-fetal transmission of Toxoplasma gondii tachyzoites acquired during pregnancy has potentially dramatic consequences for the fetus. Current…”
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Bispecific antibodies tethering innate receptors induce human tolerant-dendritic cells and regulatory T cells by Lamendour, Lucille, Gilotin, Mäelle, Deluce-Kakwata Nkor, Nora, Lakhrif, Zineb, Meley, Daniel, Poupon, Anne, Laboute, Thibaut, di Tommaso, Anne, Pin, Jean-Jacques, Mulleman, Denis, Le Mélédo, Guillaume, Aubrey, Nicolas, Watier, Hervé, Velge-Roussel, Florence

“…There is an urgent need for alternative therapies targeting human dendritic cells (DCs) that could reverse inflammatory syndromes in many autoimmune and…”
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Targeted Delivery of Toxoplasma gondii Antigens to Dendritic Cells Promote Immunogenicity and Protective Efficiency against Toxoplasmosis by Lakhrif, Zineb, Moreau, Alexis, Hérault, Bruno, Di-Tommaso, Anne, Juste, Matthieu, Moiré, Nathalie, Dimier-Poisson, Isabelle, Mévélec, Marie-Noëlle, Aubrey, Nicolas

“…Toxoplasmosis is a major public health problem and the development of a human vaccine is of high priority. Efficient vaccination against requires both a…”
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Angiotensin II facilitates breast cancer cell migration and metastasis by Rodrigues-Ferreira, Sylvie, Abdelkarim, Mohamed, Dillenburg-Pilla, Patricia, Luissint, Anny-Claude, di-Tommaso, Anne, Deshayes, Frédérique, Pontes, Carmen Lucia S, Molina, Angie, Cagnard, Nicolas, Letourneur, Franck, Morel, Marina, Reis, Rosana I, Casarini, Dulce E, Terris, Benoit, Couraud, Pierre-Olivier, Costa-Neto, Claudio M, Di Benedetto, Mélanie, Nahmias, Clara

“…Breast cancer metastasis is a leading cause of death by malignancy in women worldwide. Efforts are being made to further characterize the rate-limiting steps…”
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Specific Cell Targeting by Toxoplasma gondii Displaying Functional Single-Chain Variable Fragment as a Novel Strategy; A Proof of Principle by Aljieli, Muna, Rivière, Clément, Lantier, Louis, Moiré, Nathalie, Lakhrif, Zineb, Boussemart, Anne-France, Cnudde, Thomas, Lajoie, Laurie, Aubrey, Nicolas, Ahmed, Elhadi M, Dimier-Poisson, Isabelle, Di-Tommaso, Anne, Mévélec, Marie-Noëlle

“…holds significant therapeutic potential; however, its nonspecific invasiveness results in off-target effects. The purpose of this study is to evaluate whether…”
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Nasal administration of recombinant Neospora caninum secreting IL-15/IL-15Rα inhibits metastatic melanoma development in lung by Battistoni, Arthur, Lantier, Louis, di Tommaso, Anne, Ducournau, Céline, Lajoie, Laurie, Samimi, Mahtab, Coënon, Loïs, Rivière, Clément, Epardaud, Mathieu, Hertereau, Leslie, Poupée-Beaugé, Agathe, Rieu, Juliette, Mévélec, Marie-Noëlle, Lee, Gordon Scott, Moiré, Nathalie, Germon, Stephanie, Dimier-Poisson, Isabelle

“…BackgroundMetastases are the leading cause of mortality in many cancer types and lungs are one of the most common sites of metastasis alongside the liver,…”
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8p22 MTUS1 gene product ATIP3 is a novel anti-mitotic protein underexpressed in invasive breast carcinoma of poor prognosis by Rodrigues-Ferreira, Sylvie, Di Tommaso, Anne, Dimitrov, Ariane, Cazaubon, Sylvie, Gruel, Nadège, Colasson, Hélène, Nicolas, André, Chaverot, Nathalie, Molinié, Vincent, Reyal, Fabien, Sigal-Zafrani, Brigitte, Terris, Benoit, Delattre, Olivier, Radvanyi, François, Perez, Franck, Vincent-Salomon, Anne, Nahmias, Clara

“…Breast cancer is a heterogeneous disease that is not totally eradicated by current therapies. The classification of breast tumors into distinct molecular…”
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Neospora caninum: a new class of biopharmaceuticals in the therapeutic arsenal against cancer by Lantier, Louis, Poupée-Beaugé, Agathe, di Tommaso, Anne, Ducournau, Céline, Epardaud, Mathieu, Lakhrif, Zineb, Germon, Stéphanie, Debierre-Grockiego, Françoise, Mévélec, Marie-Noëlle, Battistoni, Arthur, Coënon, Loïs, Deluce-Kakwata-Nkor, Nora, Velge-Roussel, Florence, Beauvillain, Céline, Baranek, Thomas, Lee, Gordon Scott, Kervarrec, Thibault, Touzé, Antoine, Moiré, Nathalie, Dimier-Poisson, Isabelle

“…BackgroundMicroorganisms that can be used for their lytic activity against tumor cells as well as inducing or reactivating antitumor immune responses are a…”
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846 Neospora caninum – an immunotherapeutic protozoan against solid cancers by Lantier, Louis, Poupee-Beauge, Agathe, Ducournau, Céline, Tommaso, Anne Di, Germon, Stéphanie, Moiré, Nathalie, Lee, Gordon, Touze, Antoine, Dimier-Poisson, Isabelle

“…BackgroundImmunotherapy induces, provides, and/or reactivates anti-tumor immune responses. Some microorganisms also can initiate response that lyzes infected…”
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A Novel Nuclear Interactor of ARF and MDM2 (NIAM) That Maintains Chromosomal Stability by Tompkins, Van S., Hagen, Jussara, Frazier, April A., Lushnikova, Tamara, Fitzgerald, Matthew P., di Tommaso, Anne, Ladeveze, Veronique, Domann, Frederick E., Eischen, Christine M., Quelle, Dawn E.

“…The ARF tumor suppressor signals through p53 and other poorly defined anti-proliferative pathways to block carcinogenesis. In a search for new regulators of…”
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Residues in the alternative reading frame tumor suppressor that influence its stability and p53-independent activities by di Tommaso, Anne, Hagen, Jussara, Tompkins, Van, Muniz, Viviane, Dudakovic, Amel, Kitzis, Alain, Ladeveze, Veronique, Quelle, Dawn E.

“…The Alternative Reading Frame (ARF) protein suppresses tumorigenesis through p53-dependent and p53-independent pathways. Most of ARF's anti-proliferative…”
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Abstract 1712: Neospora caninum: An immunotherapeutic protozoan against cancer by Lantier, Louis, Poupée-Beaugé, Agathe, Tommaso, Anne Di, Ducournau, Céline, Germon, Stéphanie, Lee, Gordon S., Touze, Antoine, moiré, Nathalie, Dimier-Poisson, Isabelle

“…Abstract Background: Immunotherapy induces, provides, and/or reactivates anti-tumor immune responses. Some microorganisms also can initiate response that lyzes…”
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A method to confer Protein L binding ability to any antibody fragment by Lakhrif, Zineb, Pugnière, Martine, Henriquet, Corinne, di Tommaso, Anne, Dimier-Poisson, Isabelle, Billiald, Philippe, Juste, Matthieu O, Aubrey, Nicolas

“…Recombinant antibody single-chain variable fragments (scFv) are difficult to purify homogeneously from a protein complex mixture. The most effective, specific…”
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ATIP3, a Novel Prognostic Marker of Breast Cancer Patient Survival, Limits Cancer Cell Migration and Slows Metastatic Progression by Regulating Microtubule Dynamics by MOLINA, Angie, VELOT, Lauriane, HONORE, Stéphane, BRAGUER, Diane, GRUEL, Nadège, VINCENT-SALOMON, Anne, DELATTRE, Olivier, SIGAL-ZAFRANI, Brigitte, ANDRE, Fabrice, TERRIS, Benoit, AKHMANOVA, Anna, DI BENEDETTO, Mélanie, GHOUINEM, Lydia, NAHMIAS, Clara, RODRIGUES-FERREIRA, Sylvie, ABDELKARIM, Mohamed, BOUCHET, Benjamin Pierre, LUISSINT, Anny-Claude, BOUHLEL, Imène, MOREL, Marina, SAPHARIKAS, Elène, DI TOMMASO, Anne

“…Metastasis, a fatal complication of breast cancer, does not fully benefit from available therapies. In this study, we investigated whether ATIP3, the major…”
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Diabody Mixture Providing Full Protection against Experimental Scorpion Envenoming with Crude Androctonus australis Venom by di Tommaso, Anne, Juste, Matthieu O., Martin-Eauclaire, Marie-France, Dimier-Poisson, Isabelle, Billiald, Philippe, Aubrey, Nicolas

“…Androctonus australis is primarily involved in envenomations in North Africa, notably in Tunisia and Algeria, and constitutes a significant public health…”
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Neospora caninum: a new class of biopharmaceuticals in the therapeutic arsenal against cancer by Lantier, Louis, Poupée-Beaugé, Agathe, Di Tommaso, Anne, Ducournau, Céline, Epardaud, Mathieu, Lakhrif, Zineb, Germon, Stéphanie, Debierre-Grockiego, Françoise, Mévélec, Marie-Noëlle, Battistoni, Arthur, Coënon, Loïs, Deluce-Kakwata-Nkor, Nora, Velge-Roussel, Florence, Beauvillain, Céline, Baranek, Thomas, Lee, Gordon Scott, Kervarrec, Thibault, Touzé, Antoine, Moiré, Nathalie, Dimier-Poisson, Isabelle

“…Background Microorganisms that can be used for their lytic activity against tumor cells as well as inducing or reactivating antitumor immune responses are a…”
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ATIP, a novel superfamily of microtubule-associated proteins by Molina, Angie, Rodrigues-Ferreira, Sylvie, Di Tommaso, Anne, Nahmias, Clara

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The ink4a/arf locus evolution in primates: characterization of three ARF sequences by Di Tommaso, Anne, Soler, Cédric, Roos, Christian, Kitzis, Alain, Ladeveze, Véronique

“…The human ink4a/arf locus encodes two cell cycle regulatory proteins - the cyclin-dependent kinase inhibitor (p16(ink4a)), and the p53 activator (ARF) -…”
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