Search Results - "di Magliano, M P"
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ER stress protein AGR2 precedes and is involved in the regulation of pancreatic cancer initiation
Published in Oncogene (01-06-2017)“…The mechanisms of initiation of pancreatic ductal adenocarcinoma (PDAC) are still largely unknown. In the present study, we analysed the role of anterior…”
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Hedgehog signalling in cancer formation and maintenance
Published in Nature reviews. Cancer (01-12-2003)“…The Hedgehog signalling pathway is essential for numerous processes during embryonic development. Members of this family of secreted proteins control cell…”
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Hedgehog is an early and late mediator of pancreatic cancer tumorigenesis
Published in Nature (23-10-2003)“…Hedgehog signalling-an essential pathway during embryonic pancreatic development, the misregulation of which has been implicated in several forms of cancer-may…”
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4
Pax8 Has a Key Role in Thyroid Cell Differentiation
Published in Proceedings of the National Academy of Sciences - PNAS (21-11-2000)“…Transformation of rat thyroid cells with polyoma virus middle T antigen results in loss of the thyroid-differentiated phenotype, measured as the expression of…”
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The activation and maintenance of Pax2 expression at the mid-hindbrain boundary is controlled by separate enhancers
Published in Development (Cambridge) (01-01-2002)“…Pax2 is the earliest known gene to be expressed throughout the mid-hindbrain region in late gastrula embryos of the mouse and is essential for the formation of…”
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The Thyroid Transcription Factor 2 (TTF-2) Is a Promoter-Specific DNA-Binding Independent Transcriptional Repressor
Published in Biochemical and biophysical research communications (18-08-2000)“…The thyroid transcription factor TTF-2 is a forkhead-containing protein involved in thyroid-specific gene expression and necessary for thyroid morphogenesis…”
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