Search Results - "di Lorenzo, Giorgia"

Taurine deficiency as a driver of aging by Singh, Parminder, Gollapalli, Kishore, Mangiola, Stefano, Schranner, Daniela, Yusuf, Mohd Aslam, Chamoli, Manish, Shi, Sting L, Lopes Bastos, Bruno, Nair, Tripti, Riermeier, Annett, Vayndorf, Elena M, Wu, Judy Z, Nilakhe, Aishwarya, Nguyen, Christina Q, Muir, Michael, Kiflezghi, Michael G, Foulger, Anna, Junker, Alex, Devine, Jack, Sharan, Kunal, Chinta, Shankar J, Rajput, Swati, Rane, Anand, Baumert, Philipp, Schönfelder, Martin, Iavarone, Francescopaolo, di Lorenzo, Giorgia, Kumari, Swati, Gupta, Alka, Sarkar, Rajesh, Khyriem, Costerwell, Chawla, Amanpreet S, Sharma, Ankur, Sarper, Nazan, Chattopadhyay, Naibedya, Biswal, Bichitra K, Settembre, Carmine, Nagarajan, Perumal, Targoff, Kimara L, Picard, Martin, Gupta, Sarika, Velagapudi, Vidya, Papenfuss, Anthony T, Kaya, Alaattin, Ferreira, Miguel Godinho, Kennedy, Brian K, Andersen, Julie K, Lithgow, Gordon J, Ali, Abdullah Mahmood, Mukhopadhyay, Arnab, Palotie, Aarno, Kastenmüller, Gabi, Kaeberlein, Matt, Wackerhage, Henning, Pal, Bhupinder, Yadav, Vijay K

“…Aging is associated with changes in circulating levels of various molecules, some of which remain undefined. We find that concentrations of circulating taurine…”
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Transgenic inhibition of interleukin-6 trans-signaling does not prevent skeletal pathologies in mucolipidosis type II mice by Westermann, Lena Marie, Baranowsky, Anke, Di Lorenzo, Giorgia, Danyukova, Tatyana, Soul, Jamie, Schwartz, Jean-Marc, Hendrickx, Gretl, Amling, Michael, Rose-John, Stefan, Garbers, Christoph, Schinke, Thorsten, Pohl, Sandra

“…Severe skeletal alterations are common symptoms in patients with mucolipidosis type II (MLII), a rare lysosomal storage disorder of childhood. We have…”
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Imbalanced cellular metabolism compromises cartilage homeostasis and joint function in a mouse model of mucolipidosis type III gamma by Westermann, Lena Marie, Fleischhauer, Lutz, Vogel, Jonas, Jenei-Lanzl, Zsuzsa, Ludwig, Nataniel Floriano, Schau, Lynn, Morellini, Fabio, Baranowsky, Anke, Yorgan, Timur A, Di Lorenzo, Giorgia, Schweizer, Michaela, de Souza Pinheiro, Bruna, Guarany, Nicole Ruas, Sperb-Ludwig, Fernanda, Visioli, Fernanda, Oliveira Silva, Thiago, Soul, Jamie, Hendrickx, Gretl, Wiegert, J Simon, Schwartz, Ida V D, Clausen-Schaumann, Hauke, Zaucke, Frank, Schinke, Thorsten, Pohl, Sandra, Danyukova, Tatyana

“…Mucolipidosis type III (MLIII) gamma is a rare inherited lysosomal storage disorder caused by mutations in encoding the γ-subunit of…”
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Diversity, Cyanotoxin Production, and Bioactivities of Cyanobacteria Isolated from Freshwaters of Greece by Gkelis, Spyros, Panou, Manthos, Konstantinou, Despoina, Apostolidis, Panagiotis, Kasampali, Antonia, Papadimitriou, Sofia, Kati, Dominiki, Di Lorenzo, Giorgia Maria, Ioakeim, Stamatia, Zervou, Sevasti-Kiriaki, Christophoridis, Christophoros, Triantis, Theodoros M, Kaloudis, Triantafyllos, Hiskia, Anastasia, Arsenakis, Minas

“…Cyanobacteria are a diverse group of photosynthetic Gram-negative bacteria that produce an array of secondary compounds with selective bioactivity against a…”
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Role of FAM134 paralogues in endoplasmic reticulum remodeling, ER-phagy, and Collagen quality control by Reggio, Alessio, Buonomo, Viviana, Berkane, Rayene, Bhaskara, Ramachandra M, Tellechea, Mariana, Peluso, Ivana, Polishchuk, Elena, Di Lorenzo, Giorgia, Cirillo, Carmine, Esposito, Marianna, Hussain, Adeela, Huebner, Antje K, Hübner, Christian A, Settembre, Carmine, Hummer, Gerhard, Grumati, Paolo, Stolz, Alexandra

“…Degradation of the endoplasmic reticulum (ER) via selective autophagy (ER-phagy) is vital for cellular homeostasis. We identify FAM134A/RETREG2 and…”
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Lysosomal Proteome and Secretome Analysis Identifies Missorted Enzymes and Their Nondegraded Substrates in Mucolipidosis III Mouse Cells by Di Lorenzo, Giorgia, Velho, Renata Voltolini, Winter, Dominic, Thelen, Melanie, Ahmadi, Shiva, Schweizer, Michaela, De Pace, Raffaella, Cornils, Kerstin, Yorgan, Timur Alexander, Grüb, Saskia, Hermans-Borgmeyer, Irm, Schinke, Thorsten, Müller-Loennies, Sven, Braulke, Thomas, Pohl, Sandra

“…Targeting of soluble lysosomal enzymes requires mannose 6-phosphate (M6P) signals whose formation is initiated by the hexameric N-acetylglucosamine…”
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Distinct Modes of Balancing Glomerular Cell Proteostasis in Mucolipidosis Type II and III Prevent Proteinuria by Sachs, Wiebke, Sachs, Marlies, Krüger, Elke, Zielinski, Stephanie, Kretz, Oliver, Huber, Tobias B, Baranowsky, Anke, Westermann, Lena Marie, Voltolini Velho, Renata, Ludwig, Nataniel Floriano, Yorgan, Timur Alexander, Di Lorenzo, Giorgia, Kollmann, Katrin, Braulke, Thomas, Schwartz, Ida Vanessa, Schinke, Thorsten, Danyukova, Tatyana, Pohl, Sandra, Meyer-Schwesinger, Catherine

“…The mechanisms balancing proteostasis in glomerular cells are unknown. Mucolipidosis (ML) II and III are rare lysosomal storage disorders associated with…”
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RETREG3/FAM134C phosphorylation by CSNK2 regulates reticulophagy during starvation by Di Lorenzo, Giorgia, Iavarone, Francescopaolo, Maddaluno, Marianna, Grumati, Paolo, Settembre, Carmine

“…Starvation is the most potent physiological inducer of autophagy, the catabolic process which degrades unessential cytosolic components to sustain cellular…”
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Acute Ankle Sprain Management: An Umbrella Review of Systematic Reviews by Gaddi, Diego, Mosca, Angelo, Piatti, Massimiliano, Munegato, Daniele, Catalano, Marcello, Di Lorenzo, Giorgia, Turati, Marco, Zanchi, Nicolò, Piscitelli, Daniele, Chui, Kevin, Zatti, Giovanni, Bigoni, Marco

“…Even though ankle sprains are among the most frequent musculoskeletal injuries seen in emergency departments, management of these injuries continues to lack…”
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Pathogenic variants in GNPTAB and GNPTG encoding distinct subunits of GlcNAc-1-phosphotransferase differentially impact bone resorption in patients with mucolipidosis type II and III by Di Lorenzo, Giorgia, Westermann, Lena M., Yorgan, Timur A., Stürznickel, Julian, Ludwig, Nataniel F., Ammer, Luise S., Baranowsky, Anke, Ahmadi, Shiva, Pourbarkhordariesfandabadi, Elham, Breyer, Sandra R., Board, Tim N., Foster, Anne, Mercer, Jean, Tylee, Karen, Velho, Renata Voltolini, Schweizer, Michaela, Renné, Thomas, Braulke, Thomas, Randon, Dévora N., Sperb-Ludwig, Fernanda, de Camargo Pinto, Louise Lapagesse, Moreno, Carolina Araujo, Cavalcanti, Denise P., Amling, Michael, Kutsche, Kerstin, Winter, Dominic, Muschol, Nicole M., Schwartz, Ida V. D., Rolvien, Tim, Danyukova, Tatyana, Schinke, Thorsten, Pohl, Sandra

“…Purpose Pathogenic variants in GNPTAB and GNPTG , encoding different subunits of GlcNAc-1-phosphotransferase, cause mucolipidosis (ML) II, MLIII alpha/beta,…”
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Phosphorylation of FAM134C by CK2 controls starvation-induced ER-phagy by Di Lorenzo, Giorgia, Iavarone, Francescopaolo, Maddaluno, Marianna, Plata-Gómez, Ana Belén, Aureli, Simone, Quezada Meza, Camila Paz, Cinque, Laura, Palma, Alessandro, Reggio, Alessio, Cirillo, Carmine, Sacco, Francesca, Stolz, Alexandra, Napolitano, Gennaro, Marin, Oriano, Pinna, Lorenzo A, Ruzzene, Maria, Limongelli, Vittorio, Efeyan, Alejo, Grumati, Paolo, Settembre, Carmine

“…Selective degradation of the endoplasmic reticulum (ER) via autophagy (ER-phagy) is initiated by ER-phagy receptors, which facilitate the incorporation of ER…”
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Regulatory events controlling ER-phagy by Iavarone, Francescopaolo, Di Lorenzo, Giorgia, Settembre, Carmine

“…Autophagy of the endoplasmic reticulum (ER), known as ER-phagy, is responsible for the degradation of ER portions by lysosomes. ER-phagy is induced in both…”
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Mice heterozygous for an osteogenesis imperfecta-linked MBTPS2 variant display a compromised subchondral osteocyte lacunocanalicular network associated with abnormal articular cartilage by Danyukova, Tatyana, Alimy, Assil-Ramin, Velho, Renata Voltolini, Yorgan, Timur A., Di Lorenzo, Giorgia, von Kroge, Simon, Tidow, Henning, Wiegert, J. Simon, Hermans-Borgmeyer, Irm, Schinke, Thorsten, Rolvien, Tim, Pohl, Sandra

“…Missense variants in the MBTPS2 gene, located on the X chromosome, have been associated with an X-linked recessive form of osteogenesis imperfecta (X-OI), an…”
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Fam134c and Fam134b shape axonal endoplasmic reticulum architecture in vivo by Iavarone, Francescopaolo, Zaninello, Marta, Perrone, Michela, Monaco, Mariagrazia, Barth, Esther, Gaedke, Felix, Pizzo, Maria Teresa, Di Lorenzo, Giorgia, Desiderio, Vincenzo, Sommella, Eduardo, Merciai, Fabrizio, Salviati, Emanuela, Campiglia, Pietro, Luongo, Livio, De Leonibus, Elvira, Rugarli, Elena, Settembre, Carmine

“…Endoplasmic reticulum (ER) remodeling is vital for cellular organization. ER-phagy, a selective autophagy targeting ER, plays an important role in maintaining…”
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Site-1 protease and lysosomal homeostasis by Velho, Renata Voltolini, De Pace, Raffaella, Klünder, Sarah, Di Lorenzo, Giorgia, Schweizer, Michaela, Braulke, Thomas, Pohl, Sandra

“…The Golgi-resident site-1 protease (S1P) is a key regulator of cholesterol homeostasis and ER stress responses by converting latent transcription factors…”
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Variation in response rates to isolated limb perfusion in different soft-tissue tumour subtypes: an international multi-centre study by Reijers, Sophie J.M., Davies, Emma, Grünhagen, Dirk J., Fiore, Marco, Honore, Charles, Rastrelli, Marco, Vassos, Nikolaos, Podleska, Lars E., Niethard, Maya, Jakob, Jens, Perhavec, Andraz, Duarte, Carlos, González, Felipe, Deroose, Jan P., Stas, Marguerite, Boecxstaens, Veerle, Schrage, Yvonne, Snow, Hayden, Algarra, Salvador Martín, Said, Hector Martinez, Garcia-Ortega, Dorian Yarih, Martin, Karla, Mattsson, Jan, Djafarrian, Reza, Di Lorenzo, Giorgia, Colombo, Chiara, Gronchi, Alessandro, Matter, Maurice, Verhoef, Cornelis, Olofsson Bagge, Roger, Hohenberger, Peter, Hayes, Andrew J., van Houdt, Winan J.

“…The aim of this study was to investigate the response rates of different extremity soft-tissue sarcoma subtypes (eSTS) after isolated limb perfusion (ILP),…”
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Imbalanced cellular metabolism compromises cartilage homeostasis and joint function in a mouse model of mucolipidosis type III gamma by Westermann, Lena M, Fleischhauer, Lutz, Vogel, Jonas, Jenei-Lanzl, Zsuzsa, Floriano Ludwig, Nataniel, Schau, Lynn, Morellini, Fabio, Baranowsky, Anke, Yorgan, Timur A, Di Lorenzo, Giorgia, Schweizer, Michaela, de Souza Pinheiro, Bruna, Guarany, Nicole Ruas, Sperb-Ludwig, Fernanda, Visioli, Fernanda, Oliveira Silva, Thiago, Soul, Jamie, Hendrickx, Gretl, Wiegert, J Simon, Schwartz, Ida V D, Clausen-Schaumann, Hauke, Zaucke, Frank, Schinke, Thorsten, Pohl, Sandra, Danyukova, Tatyana

“…Mucolipidosis type III (MLIII) gamma is a rare inherited lysosomal storage disorder caused by mutations in GNPTG encoding the γ-subunit of…”
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