Search Results - "di Fonzo, Andrea"

Sunlight‐Driven Synthesis of Triarylethylenes (TAEs) via Metal‐Free Mizoroki–Heck‐Type Coupling by Onuigbo, Louis, Raviola, Carlotta, Di Fonzo, Andrea, Protti, Stefano, Fagnoni, Maurizio

“…A protocol for the preparation of substituted triarylethylenes (TAEs) was developed by using arylazo sulfones as substrates in the presence of…”
Get full text

Structural Insights into the Iodothyronine Deiodinase 2 Catalytic Core and Deiodinase Catalysis and Dimerization by Towell, Holly, Braun, Doreen, Brol, Alexander, di Fonzo, Andrea, Rijntjes, Eddy, Köhrle, Josef, Schweizer, Ulrich, Steegborn, Clemens

“…Iodothyronine deiodinases (Dio) are selenocysteine-containing membrane enzymes that activate and inactivate the thyroid hormones (TH) through reductive iodide…”
Get full text

Novel mitochondrial protein interactors of immunoglobulin light chains causing heart amyloidosis by Lavatelli, Francesca, Imperiini, Esther, Orrù, Stefania, Rognoni, Paola, Sarnataro, Daniela, Palladini, Giuseppina, Malpasso, Giuseppe, Soriano, Maria Eugenia, Di Fonzo, Andrea, Valentini, Veronica, Gnecchi, Massimiliano, Perlini, Stefano, Salvatore, Francesco, Merlini, Giampaolo

“…ABSTRACT In immunoglobulin (Ig) light‐chain (LC) (AL) amyloidosis, AL deposition translates into life‐threatening cardiomyopathy. Clinical and experimental…”
Get full text

Molecular Mechanism of Sirtuin 1 Inhibition by Human Immunodeficiency Virus 1 Tat Protein by Adolph, Ramona S, Beck, Eileen, Schweimer, Kristian, Di Fonzo, Andrea, Weyand, Michael, Rösch, Paul, Wöhrl, Birgitta M, Steegborn, Clemens

“…Sirtuins are NAD -dependent protein lysine deacylases implicated in metabolic regulation and aging-related dysfunctions. The nuclear isoform Sirt1 deacetylates…”
Get full text

Systemic amyloidoses and proteomics: The state of the art by Lavatelli, Francesca, di Fonzo, Andrea, Palladini, Giovanni, Merlini, Giampaolo

“…[Display omitted] •Proteomics is an established approach for diagnostic amyloid typing.•Mass spectrometry-based methods to analyze amyloid precursors have been…”
Get full text

Mutations of the CK2 phosphorylation site of Sic1 affect cell size and S‐Cdk kinase activity in Saccharomyces cerevisiae by Coccetti, Paola, Rossi, Riccardo L., Sternieri, Flora, Porro, Danilo, Russo, Gian Luigi, Di Fonzo, Andrea, Magni, Fulvio, Vanoni, Marco, Alberghina, Lilia

“…Summary By sequence analysis we found an amino acid stretch centred on Serine201 matching a stringent CK2 consensus site within the C‐terminal, inhibitory…”
Get full text

A Caenorhabditis elegans–based assay recognizes immunoglobulin light chains causing heart amyloidosis by Diomede, Luisa, Rognoni, Paola, Lavatelli, Francesca, Romeo, Margherita, del Favero, Elena, Cantù, Laura, Ghibaudi, Elena, di Fonzo, Andrea, Corbelli, Alessandro, Fiordaliso, Fabio, Palladini, Giovanni, Valentini, Veronica, Perfetti, Vittorio, Salmona, Mario, Merlini, Giampaolo

“…Poor prognosis and limited therapeutic options characterize immunoglobulin light-chain (AL) amyloidosis with major heart involvement. Reliable experimental…”
Get full text

Biochemical markers in early diagnosis and management of systemic amyloidoses by Lavatelli, Francesca, Albertini, Riccardo, Di Fonzo, Andrea, Palladini, Giovanni, Merlini, Giampaolo

“…Systemic amyloid diseases are characterized by widespread protein deposition as amyloid fibrils. Precise diagnostic framing is the prerequisite for a correct…”
Get more information

Crystal structure of human CDC7 kinase in complex with its activator DBF4 by Hughes, Siobhan, Elustondo, Frédéric, Di Fonzo, Andrea, Leroux, Frédéric G, Wong, Ai C, Snijders, Ambrosius P, Matthews, Stephen J, Cherepanov, Peter

“…The kinase CDC7 is essential for replication initiation in eukaryote organisms. To exert its function, CDC7 requires its activator, DBF4. Now the crystal…”
Get full text

Structural Analysis of the RZZ Complex Reveals Common Ancestry with Multisubunit Vesicle Tethering Machinery by Çivril, Filiz, Wehenkel, Annemarie, Giorgi, Federico M., Santaguida, Stefano, Di Fonzo, Andrea, Grigorean, Gabriela, Ciccarelli, Francesca D., Musacchio, Andrea

“…The RZZ complex recruits dynein to kinetochores. We investigated structure, topology, and interactions of the RZZ subunits (ROD, ZWILCH, and ZW10) in vitro,…”
Get full text

Investigating heart-specific toxicity of amyloidogenic immunoglobulin light chains: A lesson from C. elegans by Diomede, Luisa, Rognoni, Paola, Lavatelli, Francesca, Romeo, Margherita, di Fonzo, Andrea, Foray, Claudia, Fiordaliso, Fabio, Palladini, Giovanni, Valentini, Veronica, Perfetti, Vittorio, Salmona, Mario, Merlini, Giampaolo

“…Abnormalities in protein folding are involved in many localized and systemic diseases, all of which are characterized by insoluble amyloid formation and…”
Get full text

Primary Cell Cultures Arising from Normal Kidney and Renal Cell Carcinoma Retain the Proteomic Profile of Corresponding Tissues by Perego, Roberto A, Bianchi, Cristina, Corizzato, Matteo, Eroini, Barbara, Torsello, Barbara, Valsecchi, Cristina, Di Fonzo, Andrea, Cordani, Nicoletta, Favini, Paolo, Ferrero, Stefano, Pitto, Marina, Sarto, Cecilia, Magni, Fulvio, Rocco, Francesco, Mocarelli, Paolo

“…Renal cell carcinoma (RCC) tissue is composed of a mixture of neoplastic and normal cells, which complicate proteome analysis. The aim of our study was to…”
Get full text

Expanding the proteome two-dimensional gel electrophoresis reference map of human renal cortex by peptide mass fingerprinting by Magni, Fulvio, Sarto, Cecilia, Valsecchi, Cristina, Casellato, Stefano, Ferrero Bogetto, Stefano, Bosari, Silvano, Di Fonzo, Andrea, Perego, Roberto A., Corizzato, Matteo, Doro, Giancarlo, Galbusera, Carmen, Rocco, Francesco, Mocarelli, Paolo, Kienle, Marzia Galli

“…Proteomics methodologies hold great promise in basic renal research and clinical nephrology. The classical approach for proteomic analysis couples…”
Get full text

Differential expression of AQP1 in microdomain-enriched membranes of renal cell carcinoma by Ticozzi-Valerio, Davide, Raimondo, Francesca, Pitto, Marina, Rocco, Francesco, Bosari, Silvano, Perego, Roberto, Sarto, Cecilia, Di Fonzo, Andrea, Bosso, Niccolò, Mocarelli, Paolo, Galli-Kienle, Marzia, Magni, Fulvio

“…Human aquaporin‐1 (AQP1) is the most studied member of the aquaporin family, acting as molecular water channel. It is also considered a differentiation marker…”
Get full text