Search Results - "di Blasio, Stefania"
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STAT Family Protein Expression and Phosphorylation State during moDC Development Is Altered by Platinum-Based Chemotherapeutics
Published in Journal of immunology research (01-01-2019)“…The STAT signaling pathway is important in dendritic cell (DC) development and function. Tumor cells can induce STAT signaling, thereby inhibiting DC…”
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Clinical Implications of Co-Inhibitory Molecule Expression in the Tumor Microenvironment for DC Vaccination: A Game of Stop and Go
Published in Frontiers in immunology (01-01-2013)“…The aim of therapeutic dendritic cell (DC) vaccines in cancer immunotherapy is to activate cytotoxic T cells to recognize and attack the tumor. T cell…”
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Preclinical exploration of combining plasmacytoid and myeloid dendritic cell vaccination with BRAF inhibition
Published in Journal of translational medicine (14-04-2016)“…Melanoma is the most lethal type of skin cancer and its incidence is progressively increasing. The introductions of immunotherapy and targeted therapies have…”
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3072 – REGULATION OF DORMANCY IN THE BONE MARROW MICROENVIRONMENT
Published in Experimental hematology (01-08-2024)“…The bone marrow (BM) microenvironment is the home of haematopoietic stem cells (HSCs) which remain mostly quiescent to maintain self-renewal potential. HSC…”
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Cancer-induced systemic pre-conditioning of distant organs: building a niche for metastatic cells
Published in Nature reviews. Cancer (10-10-2024)“…From their early genesis, tumour cells integrate with the surrounding normal cells to form an abnormal structure that is tightly integrated with the host…”
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Bidirectional activation of stem-like programs between metastatic cancer and alveolar type 2 cells within the niche
Published in Developmental cell (23-09-2024)“…A key step for metastatic outgrowth involves the generation of a deeply altered microenvironment (niche) that supports the malignant behavior of cancer cells…”
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Human CD1c+ DCs are critical cellular mediators of immune responses induced by immunogenic cell death
Published in Oncoimmunology (02-08-2016)“…Chemotherapeutics, including the platinum compounds oxaliplatin (OXP) and cisplatin (CDDP), are standard care of treatment for cancer. Although chemotherapy…”
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Multispectral imaging for highly accurate analysis of tumour‐infiltrating lymphocytes in primary melanoma
Published in Histopathology (01-03-2017)“…Aims The quality and quantity of the infiltration of immune cells into tumour tissues have substantial impacts on patients’ clinical outcomes, and are…”
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