Search Results - "der Spek, Peter van"

The preconception Mediterranean dietary pattern in couples undergoing in vitro fertilization/intracytoplasmic sperm injection treatment increases the chance of pregnancy by Vujkovic, Marijana, B.Sc, de Vries, Jeanne H., Ph.D, Lindemans, Jan, Ph.D, Macklon, Nick S., Ph.D, van der Spek, Peter J., Ph.D, Steegers, Eric A.P., Ph.D, Steegers-Theunissen, Régine P.M., Ph.D

“…Objective To investigate associations between preconception dietary patterns and IVF/intracytoplasmic sperm injection (ICSI) outcomes validated by biomarkers…”
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Inactivation of IL11 Signaling Causes Craniosynostosis, Delayed Tooth Eruption, and Supernumerary Teeth by Nieminen, Pekka, Morgan, Neil V., Fenwick, Aimée L., Parmanen, Satu, Veistinen, Lotta, Mikkola, Marja L., van der Spek, Peter J., Giraud, Andrew, Judd, Louise, Arte, Sirpa, Brueton, Louise A., Wall, Steven A., Mathijssen, Irene M.J., Maher, Eamonn R., Wilkie, Andrew O.M., Kreiborg, Sven, Thesleff, Irma

“…Craniosynostosis and supernumerary teeth most often occur as isolated developmental anomalies, but they are also separately manifested in several malformation…”
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Evaluation of Immunohistochemical Markers, CK17 and SOX2, as Adjuncts to p53 for the Diagnosis of Differentiated Vulvar Intraepithelial Neoplasia (dVIN) by Dasgupta, Shatavisha, Koljenović, Senada, van den Bosch, Thierry P P, Swagemakers, Sigrid M A, van der Hoeven, Nick M A, van Marion, Ronald, van der Spek, Peter J, van Doorn, Helena C, van Kemenade, Folkert J, Ewing-Graham, Patricia C

“…Histological diagnosis of differentiated vulvar intraepithelial neoplasia (dVIN), the precursor of human papillomavirus (HPV)-independent vulvar squamous cell…”
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Identification of candidate genes for developmental colour agnosia in a single unique family by Nijboer, Tanja C. W, Hessel, Ellen V. S, van Haaften, Gijs W, van Zandvoort, Martine J, van der Spek, Peter J, Troelstra, Christine, de Kovel, Carolien G. F, Koeleman, Bobby P. C, van der Zwaag, Bert, Brilstra, Eva H, Burbach, J. Peter H

“…Colour agnosia is a disorder that impairs colour knowledge (naming, recognition) despite intact colour perception. Previously, we have identified the first and…”
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Functional Analysis of Genetic Variation in the SECIS Element of Thyroid Hormone Activating Type 2 Deiodinase by Zevenbergen, Chantal, Groeneweg, Stefan, Swagemakers, Sigrid M A, de Jong, Arthur, Medici-Van den Herik, Evita, Rispens, Madzy, Klootwijk, Wim, Medici, Marco, de Rijke, Yolanda B, Meima, Marcel E, Larsen, P Reed, Chavatte, Laurent, Venter, Deon, Peeters, Robin P, Van der Spek, Peter J, Visser, W Edward

“…Abstract Context Thyroid hormone is important for normal brain development. The type 2 deiodinase (D2) controls thyroid hormone action in the brain by…”
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Glut1/SLC2A1 is crucial for the development of the blood-brain barrier in vivo by Zheng, Ping-Pin, Romme, Edwin, Spek, Peter J. van der, Dirven, Clemens M.F., Willemsen, Rob, Kros, Johan M.

“…Objective The overall permeability of the blood‐brain barrier (BBB) is regulated by specialized cerebral endothelial cells and their junctional complexes,…”
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Immunologic mechanisms associated with STAT6 gain-of-function variant identified in early-onset allergies by Suratannon, Narissara, Dik, Willem, Israsena, Nipan, Ingrungruanglert, Praewphan, Dalm, Virgil A.S.H., Buranapraditkun, Supranee, Swagemakers, Sigrid, IJspeert, Hanna, van der Spek van der Spek, Peter J., Chatchatee, Pantipa, van Hagen, Martin

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Galaxy mothur Toolset (GmT): a user-friendly application for 16S rRNA gene sequencing analysis using mothur by Hiltemann, Saskia D, Boers, Stefan A, van der Spek, Peter J, Jansen, Ruud, Hays, John P, Stubbs, Andrew P

“…Abstract Background The determination of microbial communities using the mothur tool suite (https://www.mothur.org) is well established. However, mothur…”
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Microarray and morphological analysis of early postnatal CRB2 mutant retinas on a pure C57BL/6J genetic background by Alves, Celso Henrique, Bossers, Koen, Vos, Rogier M, Essing, Anke H W, Swagemakers, Sigrid, van der Spek, Peter J, Verhaagen, Joost, Wijnholds, Jan

“…In humans, the Crumbs homologue-1 (CRB1) gene is mutated in progressive types of autosomal recessive retinitis pigmentosa and Leber congenital amaurosis. The…”
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First trimester physiological development of the fetal foot position using three‐dimensional ultrasound in virtual reality by Bogers, Hein, Rifouna, Maria S., Cohen‐Overbeek, Titia E., Koning, Anton H. J., Willemsen, Sten P., van der Spek, Peter J., Steegers‐Theunissen, Régine P. M., Exalto, Niek, Steegers, Eric A. P.

“…Aim In anatomic studies of the embryo, it has been established that during the development of the lower limb, several changes in foot position can be observed…”
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Fusion transcripts and their genomic breakpoints in polyadenylated and ribosomal RNA–minus RNA sequencing data by Hoogstrate, Youri, Komor, Malgorzata A, Böttcher, René, van Riet, Job, van de Werken, Harmen J G, van Lieshout, Stef, Hoffmann, Ralf, van den Broek, Evert, Bolijn, Anne S, Dits, Natasja, Sie, Daoud, van der Meer, David, Pepers, Floor, Bangma, Chris H, van Leenders, Geert J L H, Smid, Marcel, French, Pim J, Martens, John W M, van Workum, Wilbert, van der Spek, Peter J, Janssen, Bart, Caldenhoven, Eric, Rausch, Christian, de Jong, Mark, Stubbs, Andrew P, Meijer, Gerrit A, Fijneman, Remond J A, Jenster, Guido W

“…Abstract Background Fusion genes are typically identified by RNA sequencing (RNA-seq) without elucidating the causal genomic breakpoints. However,…”
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Metabolomic Signatures for the Effects of Weight Loss Interventions on Severe Obesity in Children and Adolescents by Sohn, Min-Ji, Chae, Woori, Ko, Jae-Sung, Cho, Joo-Youn, Kim, Ji-Eun, Choi, Ji-Yeob, Jang, Han-Byul, Lee, Hye-Ja, Park, Sang-Ick, Park, Kyung-Hee, van der Spek, Peter J, Moon, Jin-Soo

“…Childhood obesity has increased worldwide, and many clinical and public interventions have attempted to reduce morbidity. We aimed to determine the metabolomic…”
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Gene expression and functional annotation of the human and mouse choroid plexus epithelium by Janssen, Sarah F, van der Spek, Sophie J F, Ten Brink, Jacoline B, Essing, Anke H W, Gorgels, Theo G M F, van der Spek, Peter J, Jansonius, Nomdo M, Bergen, Arthur A B

“…The choroid plexus epithelium (CPE) is a lobed neuro-epithelial structure that forms the outer blood-brain barrier. The CPE protrudes into the brain ventricles…”
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Automated Selection of Hotspots (ASH): enhanced automated segmentation and adaptive step finding for Ki67 hotspot detection in adrenal cortical cancer by Lu, Hao, Papathomas, Thomas G, van Zessen, David, Palli, Ivo, de Krijger, Ronald R, van der Spek, Peter J, Dinjens, Winand N M, Stubbs, Andrew P

“…In prognosis and therapeutics of adrenal cortical carcinoma (ACC), the selection of the most active areas in proliferative rate (hotspots) within a slide and…”
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A subtype of childhood acute lymphoblastic leukaemia with poor treatment outcome: a genome-wide classification study by Den Boer, Monique L, Dr, van Slegtenhorst, Marjon, PhD, De Menezes, Renée X, PhD, Cheok, Meyling H, PhD, Buijs-Gladdines, Jessica GCAM, BSc, Peters, Susan TCJM, BSc, Van Zutven, Laura JCM, PhD, Beverloo, H Berna, PhD, Van der Spek, Peter J, Prof, Escherich, Gaby, PhD, Horstmann, Martin A, Prof, Janka-Schaub, Gritta E, Prof, Kamps, Willem A, Prof, Evans, William E, Prof, Pieters, Rob, Prof

“…Summary Background Genetic subtypes of acute lymphoblastic leukaemia (ALL) are used to determine risk and treatment in children. 25% of precursor B-ALL cases…”
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A new strategy to identify and annotate human RPE-specific gene expression by Booij, Judith C, ten Brink, Jacoline B, Swagemakers, Sigrid M A, Verkerk, Annemieke J M H, Essing, Anke H W, van der Spek, Peter J, Bergen, Arthur A B

“…To identify and functionally annotate cell type-specific gene expression in the human retinal pigment epithelium (RPE), a key tissue involved in age-related…”
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Plasticity mechanisms of genetically distinct Purkinje cells by Voerman, Stijn, Broersen, Robin, Swagemakers, Sigrid M. A., De Zeeuw, Chris I., Spek, Peter J.

“…Despite its uniform appearance, the cerebellar cortex is highly heterogeneous in terms of structure, genetics and physiology. Purkinje cells (PCs), the…”
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Functional annotation of the human retinal pigment epithelium transcriptome by Booij, Judith C, van Soest, Simone, Swagemakers, Sigrid M A, Essing, Anke H W, Verkerk, Annemieke J M H, van der Spek, Peter J, Gorgels, Theo G M F, Bergen, Arthur A B

“…To determine level, variability and functional annotation of gene expression of the human retinal pigment epithelium (RPE), the key tissue involved in retinal…”
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On the origin of proteins in human drusen: The meet, greet and stick hypothesis by Bergen, Arthur A., Arya, Swati, Koster, Céline, Pilgrim, Matthew G., Wiatrek-Moumoulidis, Dagmara, van der Spek, Peter J., Hauck, Stefanie M., Boon, Camiel J.F., Emri, Eszter, Stewart, Alan J., Lengyel, Imre

“…Retinal drusen formation is not only a clinical hallmark for the development of age-related macular degeneration (AMD) but also for other disorders, such as…”
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CRISPRs in the human genome are differentially expressed between malignant and normal adjacent to tumor tissue by van Riet, Job, Saha, Chinmoy, Strepis, Nikolaos, Brouwer, Rutger W. W., Martens-Uzunova, Elena S., van de Geer, Wesley S., Swagemakers, Sigrid M. A., Stubbs, Andrew, Halimi, Yassir, Voogd, Sanne, Tanmoy, Arif Mohammad, Komor, Malgorzata A., Hoogstrate, Youri, Janssen, Bart, Fijneman, Remond J. A., Niknafs, Yashar S., Chinnaiyan, Arul M., van IJcken, Wilfred F. J., van der Spek, Peter J., Jenster, Guido, Louwen, Rogier

“…Clustered Regularly Interspaced Short Palindromic Repeats (CRISPRs) have been identified in bacteria, archaea and mitochondria of plants, but not in…”
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