Search Results - "den Heijer, M."
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Associations between sex hormones, sleep problems and depression: A systematic review
Published in Neuroscience and biobehavioral reviews (01-11-2020)“…•The lifetime risk of depression and sleep problems is twice as high in women.•Sex hormones may play a role but specific effects of these hormones are not…”
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Cross‐sex hormone therapy in transgender persons affects total body weight, body fat and lean body mass: a meta‐analysis
Published in Andrologia (01-06-2017)“…Summary Weight gain and body fat increase the risk of cardiometabolic disease. Cross‐sex hormone therapy in transgender persons leads to changes in body weight…”
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Homocysteine, MTHFR and risk of venous thrombosis: a meta‐analysis of published epidemiological studies
Published in Journal of thrombosis and haemostasis (01-02-2005)“…Context: It has been suggested that elevated total plasma homocysteine levels are associated with the risk of venous thrombosis. Objective: To assess the…”
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4
Age- and gender-specific reference values of estimated GFR in Caucasians: The Nijmegen Biomedical Study
Published in Kidney international (01-09-2007)“…The Nijmegen Biomedical Study is a population-based cross-sectional study conducted in the eastern part of the Netherlands. As part of the overall study, we…”
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The effect of circulating iron on barrier integrity of primary human endothelial cells
Published in Scientific reports (06-10-2023)“…Iron is hypothesized to be one of the contributors to cardiovascular disease and its levels in the circulation may correlate with cardiovascular risk. The aim…”
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Sexual orientation in transgender individuals: results from the longitudinal ENIGI study
Published in International journal of impotence research (01-11-2020)“…Transgender people and their next-of-kin may request information on sexual orientation and preferred partners during hormonal affirming process. Although…”
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Effects of hormonal treatment on dermatological outcome in transgender people: a multicentric prospective study (ENIGI)
Published in Journal of endocrinological investigation (01-04-2023)“…Purpose The aim of our study was to assess dermatological changes in transgender people after the start of gender-affirming hormonal treatment (GAHT) and to…”
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False negatives in GBA1 sequencing due to polymerase dependent allelic imbalance
Published in Scientific reports (08-01-2021)“…A variant in the GBA1 gene is one of the most common genetic risk factors to develop Parkinson’s disease (PD). Here the serendipitous finding is reported of a…”
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The role of fat mass and skeletal muscle mass in knee osteoarthritis is different for men and women: the NEO study
Published in Osteoarthritis and cartilage (01-02-2014)“…Summary Objective To investigate if the amount of fat mass (FM) or skeletal muscle mass (SMM) is more strongly associated with knee osteoarthritis (OA), in…”
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Fatty acid intake and its dietary sources in relation with markers of type 2 diabetes risk: The NEO study
Published in European journal of clinical nutrition (01-02-2017)“…Objective: The aim of this study was to examine the relations between intakes of total, saturated, mono-unsaturated, poly-unsaturated and trans fatty acids…”
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Inflammation in deep vein thrombosis and the development of post‐thrombotic syndrome: a prospective study
Published in Journal of thrombosis and haemostasis (01-04-2009)“…Background: The aim of this study was to investigate whether inflammatory markers (interleukin‐6 [IL‐6] and C‐reactive protein [CRP]) in the acute phase of…”
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A randomized single and multiple ascending dose study in healthy volunteers of LTI‐291, a centrally penetrant glucocerebrosidase activator
Published in British journal of clinical pharmacology (01-09-2021)“…Aims A mutation in the GBA1 gene is the most common genetic risk factor for developing Parkinson's disease. GBA1 encodes the lysosomal enzyme…”
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Apolipoprotein B, non‐HDL cholesterol and LDL cholesterol for identifying individuals at increased cardiovascular risk
Published in Journal of internal medicine (01-12-2010)“… Holewijn S, den Heijer M, Swinkels DW, Stalenhoef AFH, de Graaf J. (Address: Division of Vascular Medicine, Department of General Internal Medicine;…”
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14
Long-term vitamin D deficiency in older adult C57BL/6 mice does not affect bone structure, remodeling and mineralization
Published in The Journal of steroid biochemistry and molecular biology (01-11-2016)“…Animal models show that vitamin D deficiency may have severe consequences for skeletal health. However, most studies have been performed in young rodents for a…”
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Blood lipid levels and prostate cancer risk; a cohort study
Published in Prostate cancer and prostatic diseases (01-12-2011)“…It has been hypothesized that blood lipid levels might be associated with prostate cancer risk. The aim of the present study was to evaluate the association…”
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Mapping evidence on the effects of gender-affirming hormone therapy on the hard and soft tissues of the craniofacial complex in transgender people: a protocol for a scoping review
Published in Systematic reviews (14-04-2021)“…Gender-affirming hormone (GAH) therapy aims to support the transition of transgender people to their gender identity. GAHs can induce changes in their…”
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Homocysteine, methylenetetrahydrofolate reductase and risk of schizophrenia: a meta-analysis
Published in Molecular psychiatry (01-02-2006)“…Elevated plasma homocysteine concentration has been suggested as a risk factor for schizophrenia, but the results of epidemiological studies have been…”
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A candidate genetic risk factor for vascular disease: a common mutation in methylenetetrahydrofolate reductase
Published in Nature genetics (01-05-1995)“…Hyperhomocysteinaemia has been identified as a risk factor for cerebrovascular, peripheral vascular and coronary heart disease. Elevated levels of plasma…”
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Brachial artery diameter is related to cardiovascular risk factors and intima-media thickness
Published in European journal of clinical investigation (01-07-2009)“…Background Previous reports showed inconsistent results about the potential role of flow‐mediated dilatation (FMD) in cardiovascular(CV) risk prediction. Few…”
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Changes in regional body fat, lean body mass and body shape in trans persons using cross-sex hormonal therapy: results from a multicenter prospective study
Published in European journal of endocrinology (01-02-2018)“…Objective Cross-sex hormonal therapy (CHT) in trans persons affects their total body fat and total lean body mass. However, it is unknown how separate body…”
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