Search Results - "den Dunnen, W. F."

Review: On TRAIL for malignant glioma therapy? by Kuijlen, J. M. A., Bremer, E., Mooij, J. J. A., Den Dunnen, W. F. A., Helfrich, W.

“…J. M. A. Kuijlen, E. Bremer, J. J. A. Mooij, W. F. A. den Dunnen and W. Helfrich (2010) Neuropathology and Applied Neurobiology36, 168–182
On TRAIL for…”
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Huntington's disease (HD): the neuropathology of a multisystem neurodegenerative disorder of the human brain by Rüb, U., Seidel, K., Heinsen, H., Vonsattel, J.P., den Dunnen, W.F., Korf, H.W.

“…Huntington's disease (HD) is an autosomal dominantly inherited, and currently untreatable, neuropsychiatric disorder. This progressive and ultimately fatal…”
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Cellular protein quality control and the evolution of aggregates in spinocerebellar ataxia type 3 (SCA3) by Seidel, K., Meister, M., Dugbartey, G. J., Zijlstra, M. P., Vinet, J., Brunt, E. R. P., van Leeuwen, F. W., Rüb, U., Kampinga, H. H., den Dunnen, W. F. A.

“…K. Seidel, M. Meister, G. J. Dugbartey, M. P. Zijlstra, J. Vinet, E. R. P. Brunt, F. W. van Leeuwen, U. Rüb, H. H. Kampinga and W. F. A. den Dunnen (2012)…”
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Diffuse, IDH-wildtype gliomas in adults with minimal histological change and isolated TERT promoter mutation: not simply CNS WHO grade 4 by Priesterbach-Ackley, L. P., Cordier, F., de Witt Hamer, P., Snijders, T. J., Robe, P. A., Küsters, B., de Leng, W. W. J., den Dunnen, W. F. A., Brandsma, D., Jansen, C., Wesseling, P., Muhlebner, A.

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Brain tumour diagnostics using a DNA methylation‐based classifier as a diagnostic support tool by Priesterbach‐Ackley, L. P., Boldt, H. B., Petersen, J. K., Bervoets, N., Scheie, D., Ulhøi, B. P., Gardberg, M., Brännström, T., Torp, S. H., Aronica, E., Küsters, B., den Dunnen, W. F. A., Vos, F. Y. F. L., Wesseling, P., Leng, W. W. J., Kristensen, B. W.

“…Aims Methylation profiling (MP) is increasingly incorporated in the diagnostic process of central nervous system (CNS) tumours at our centres in The…”
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A heritable form of SMARCE1-related meningiomas with important implications for follow-up and family screening by Gerkes, E. H., Fock, J. M., den Dunnen, W. F. A., van Belzen, M. J., van der Lans, C. A., Hoving, E. W., Fakkert, I. E., Smith, M. J., Evans, D. G., Olderode-Berends, M. J. W.

“…Childhood meningiomas are rare. Recently, a new hereditary tumor predisposition syndrome has been discovered, resulting in an increased risk for spinal and…”
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Polyglutamine aggregation in Huntington's disease and spinocerebellar ataxia type 3: similar mechanisms in aggregate formation by Seidel, K., Siswanto, S., Fredrich, M., Bouzrou, M., Brunt, E. R., van Leeuwen, F. W., Kampinga, H. H., Korf, H. -W., Rüb, U., den Dunnen, W. F. A.

“…Aims Polyglutamine (polyQ) diseases are characterized by the expansion of a polymorphic glutamine sequence in disease‐specific proteins and exhibit aggregation…”
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Fluorescence detection of pituitary neuroendocrine tumour during endoscopic transsphenoidal surgery using bevacizumab-800CW: a non-randomised, non-blinded, single centre feasibility and dose finding trial [DEPARTURE trial] by Schmidt, I, Vergeer, R A, Postma, M R, Berg, G van den, Sterkenburg, A J, Korsten-Meijer, A G W, Feijen, R A, Kruijff, S, Beek, A P van, Dunnen, W F A den, Robinson, D J, Dijk, J M C van, Nagengast, W B, Kuijlen, J M A

“…Achieving endocrine remission by gross total resection is challenging in pituitary neuroendocrine tumours (PitNETs) with cavernous sinus invasion. This study…”
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The human premotor oculomotor brainstem system - can it help to understand oculomotor symptoms in Huntington's disease? by Rüb, U., Heinsen, H., Brunt, E. R., Landwehrmeyer, B., Den Dunnen, W. FA, Gierga, K., Deller, T.

“…Recent progress in oculomotor research has enabled new insights into the functional neuroanatomy of the human premotor oculomotor brainstem network. In the…”
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SSTR-2 as a potential tumour-specific marker for fluorescence-guided meningioma surgery by Dijkstra, B. M., Motekallemi, A., den Dunnen, W. F. A., Jeltema, J. R., van Dam, G. M., Kruyt, F. A. E., Groen, R. J. M.

“…Background Meningiomas are the most frequently occurring primary intracranial tumours in adults. Surgical removal can only be curative by complete resection;…”
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The HSPB8-BAG3 chaperone complex is upregulated in astrocytes in the human brain affected by protein aggregation diseases by Seidel, K., Vinet, J., den Dunnen, W. F. A., Brunt, E. R., Meister, M., Boncoraglio, A., Zijlstra, M. P., Boddeke, H. W. G. M., Rüb, U., Kampinga, H. H., Carra, S.

“…K. Seidel, J. Vinet, W. F. A. den Dunnen, E. R. Brunt, M. Meister, A. Boncoraglio, M. P. Zijlstra, H. W. G. M. Boddeke, U. Rüb, H. H. Kampinga and S. Carra…”
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Inhibition of formyl peptide receptor in high-grade astrocytoma by CHemotaxis Inhibitory Protein of S. aureus by Boer, J C, Domanska, U M, Timmer-Bosscha, H, Boer, I G J, de Haas, C J C, Joseph, J V, Kruyt, F A E, de Vries, E G E, den Dunnen, W F A, van Strijp, J A G, Walenkamp, A M E

“…Background: High-grade astrocytomas are malignant brain tumours that infiltrate the surrounding brain tissue and have a poor prognosis. Activation of formyl…”
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Microenvironment involved in FPR1 expression by human glioblastomas by Boer, J. C., van Marion, D. M. S., Joseph, J. V., Kliphuis, N. M., Timmer-Bosscha, H., van Strijp, J. A. G., de Vries, E. G. E., den Dunnen, W. F. A., Kruyt, F. A. E., Walenkamp, A. M. E.

“…Formyl peptide receptor 1 (FPR1) activity in U87 glioblastoma (GBM) cells contributes to tumor cell motility. The present study aimed to evaluate the FPR1…”
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Tumour vasculature and angiogenic profile of paediatric pilocytic astrocytoma; is it much different from glioblastoma? by Sie, M., De Bont, E. S. J. M., Scherpen, F. J. G., Hoving, E. W., Den Dunnen, W. F. A.

“…M. Sie, E. S. J. M. de Bont, F. J. G. Scherpen, E. W. Hoving and W. F. A. den Dunnen (2010) Neuropathology and Applied Neurobiology36, 636–647
Tumour…”
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The chemokine network, a newly discovered target in high grade gliomas by Domanska, U.M, Kruizinga, R.C, den Dunnen, W.F.A, Timmer-Bosscha, H, de Vries, E.G.E, Walenkamp, A.M.E

“…Abstract Chemokines are small cytokines, characterised by their ability to induce directional migration of cells by binding to chemokine receptors. They are…”
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Vascular endothelial growth factor receptor 2 (VEGFR-2) signalling activity in paediatric pilocytic astrocytoma is restricted to tumour endothelial cells by Sikkema, A. H., de Bont, E. S. J. M., Molema, G., Dimberg, A., Zwiers, P. J., Diks, S. H., Hoving, E. W., Kamps, W. A., Peppelenbosch, M. P., den Dunnen, W. F. A.

“…A. H. Sikkema, E. S. J. M. de Bont, G. Molema, A. Dimberg, P. J. Zwiers, S. H. Diks, E. W. Hoving, W. A. Kamps, M. P. Peppelenbosch and W. F. A. den Dunnen…”
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The role of CXC chemokine ligand (CXCL)12-CXC chemokine receptor (CXCR)4 signalling in the migration of neural stem cells towards a brain tumour by Van Der Meulen, A. A. E., Biber, K., Lukovac, S., Balasubramaniyan, V., Den Dunnen, W. F. A., Boddeke, H. W. G. M., Mooij, J. J. A.

“…Aims: It has been shown that neural stem cells (NSCs) migrate towards areas of brain injury or brain tumours and that NSCs have the capacity to track…”
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TGF-β is an inducer of ZEB1-dependent mesenchymal transdifferentiation in glioblastoma that is associated with tumor invasion by Joseph, J V, Conroy, S, Tomar, T, Eggens-Meijer, E, Bhat, K, Copray, S, Walenkamp, A M E, Boddeke, E, Balasubramanyian, V, Wagemakers, M, den Dunnen, W F A, Kruyt, F A E

“…Different molecular subtypes of glioblastoma (GBM) have been recently identified, of which the mesenchymal subtype is associated with worst prognoses. Here, we…”
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Spinal hemorrhages are associated with early neonatal motor function loss in human spina bifida aperta by Sival, D.A, Verbeek, R.J, Brouwer, O.F, Sollie, K.M, Bos, A.F, den Dunnen, W.F.A

“…Abstract Background In spina bifida aperta (SBA), leg movements caudal to the meningomyelocele are present in utero , but they disappear shortly after birth…”
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Muscle ultrasound density in human fetuses with spina bifida aperta by Verbeek, R.J, van der Hoeven, J.H, Sollie, K.M, Maurits, N.M, Bos, A.F, den Dunnen, W.F.A, Brouwer, O.F, Sival, D.A

“…Abstract Background In fetal spina bifida aperta (SBA), leg movements caudal to the meningomyelocele (MMC) are transiently present, but they disappear shortly…”
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