Search Results - "den Brok, Melina G.H.E."

Apathy in Parkinson's disease: A systematic review and meta-analysis by den Brok, Melina G.H.E., van Dalen, Jan Willem, van Gool, Willem A., Moll van Charante, Eric P., de Bie, Rob M.A., Richard, Edo

“…Apathy is a frequently reported neuropsychiatric symptom in Parkinson's disease (PD), but its prevalence and clinical correlates are debated. We aimed to…”
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NADP+ -dependent IDH1R132 mutation and its relevance for glioma patient survival by Baldewpersad Tewarie, Nishita M.S, Burgers, Ilsa A.V, Dawood, Yousif, den Boon, Hannah C, den Brok, Melina G.H.E, Klunder, Jet H, Koopmans, Kristijn B, Rademaker, Emma, van den Broek, Hans B, van den Bersselaar, Sil M, Witjes, Julia J, Van Noorden, Cornelis J.F, Atai, Nadia A

“…Abstract The isocitrate dehydrogenase 1 (IDH1) mutation occurs in high frequency in glioma and secondary glioblastoma (GBM). Mutated IDH1 produces the…”
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Bayes analysis supports null hypothesis of anti‐amyloid beta therapy in Alzheimer's disease by Richard, Edo, den Brok, Melina G.H.E., Gool, Willem A.

“…Numerous clinical trials of anti‐amyloid beta (Aβ) immunotherapy in Alzheimer's disease have been performed. None of these have provided convincing evidence…”
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Antihypertensive Medication Classes and the Risk of Dementia: A Systematic Review and Network Meta-Analysis by den Brok, Melina G.H.E., van Dalen, Jan Willem, Abdulrahman, Hanna, Larson, Eric B., van Middelaar, Tessa, van Gool, Willem A., Moll van Charante, Eric P., Richard, Edo

“…To systematically review and synthesize the evidence on differential associations between antihypertensive medication (AHM) classes and the risk of incident…”
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Low Values for Blood Pressure, BMI, and Non-HDL Cholesterol and the Risk of Late-Life Dementia by den Brok, Melina GHE, Eggink, Esmé, Hoevenaar-Blom, Marieke P, van Gool, Willem A, Moll van Charante, Eric P, Richard, Edo, Willem van Dalen, Jan

“…Low values of blood pressure, body mass index (BMI), and non-high-density lipoprotein (HDL) cholesterol have all been associated with increased dementia risk…”
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The effect of cardiovascular risk on disease progression in de novo Parkinson's disease patients: An observational analysis by Oosterwegel, Max J, Krijthe, Jesse H, den Brok, Melina G H E, van den Heuvel, Lieneke, Richard, Edo, Heskes, Tom, Bloem, Bastiaan R, Evers, Luc J W

“…Currently available treatment options for Parkinson's disease are symptomatic and do not alter the course of the disease. Recent studies have raised the…”
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Prevalence and risk factors of symptomatic carotid stenosis in patients with recent transient ischaemic attack or ischaemic stroke in the Netherlands by den Brok, Melina GHE, Kuhrij, Laurien S, Roozenbeek, Bob, van der Lugt, Aad, Hilkens, Pieter HE, Dippel, Diederik WJ, Nederkoorn, Paul J

“…Introduction Literature on prevalence of symptomatic internal carotid artery stenosis is scarce and heterogeneous. Prevalence may have decreased in recent…”
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Year-by-Year Blood Pressure Variability From Midlife to Death and Lifetime Dementia Risk by den Brok, Melina G H E, van Dalen, Jan Willem, Marcum, Zachary A, Busschers, Wim B, van Middelaar, Tessa, Hilkens, Nina, Klijn, Catharina J M, Moll van Charante, Eric P, van Gool, Willem A, Crane, Paul K, Larson, Eric B, Richard, Edo

“…High visit-to-visit blood pressure variability (BPV) in late life may reflect increased dementia risk better than mean systolic blood pressure (SBP). Evidence…”
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The Effect of Multidomain Interventions on Global Cognition, Symptoms of Depression and Apathy — A Pooled Analysis of Two Randomized Controlled Trials by den Brok, Melina G. H. E., Hoevenaar-Blom, M. P., Coley, N., Andrieu, S., van Dalen, J., Meiller, Y., Guillemont, J., Brayne, C., van Gool, W. A., Moll van Charante, E. P., Richard, E.

“…Background Cardiovascular risk factors and lifestyle factors are associated with an increased risk of cognitive decline and dementia in observational studies,…”
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