Search Results - "den Besten, C."

Skeletal stability after mandibular advancement in bilateral sagittal split osteotomies during adolescence by den Besten, C.A, Mensink, G, van Merkesteyn, J.P.R

“…Abstract Bilateral sagittal split osteotomy (BSSO) is the most frequently performed surgery for correcting mandibular retrognathia. Few studies have reported…”
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G.P.108 by den Besten, C, Jones, S, Wilmer, M, Masereeuw, R, Campion, G

“…Prosensa Therapeutics is developing 2′ O -modified phosphorothioate antisense oligonucleotides (AONs) to provide a mutation-specific therapy in the treatment…”
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G.P.107 by den Besten, C, Steevels, T, Ekhart, P, Jones, S, Gibbs, S, Campion, G

“…Injection site reactions (ISR) are commonly reported following subcutaneous (SC) administration of oligonucleotides (ONs). Development of ISRs following SC…”
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High throughput screening of Pd-alloys for H2 separation membranes studied by hydrogenography and CVM by WESTERWAAL, R. J, DEN BESTEN, C, SLAMAN, M, DAM, B, NANU, D. E, BÖTTGER, A. J, HAIJE, W. G

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Resting metabolic rate and diet-induced thermogenesis in abdominal and gluteal-femoral obese women before and after weight reduction by den Besten, C, Vansant, G, Weststrate, JA, Deurenberg, P

“…Fifteen premenopausal obese women, seven abdominal obese (AO) and eight gluteal-femoral obese (GFO), followed an energy-reduced diet of 1000 kcal/d (4.2 MJ/d)…”
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The liver, kidney, and thyroid toxicity of chlorinated benzenes by den Besten, C, Vet, J J, Besselink, H T, Kiel, G S, van Berkel, B J, Beems, R, van Bladeren, P J

“…The acute toxicity of a number of chlorinated benzenes, ranging from monosubstituted to pentasubstituted benzenes, was studied in rats. Toxic effects on the…”
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Active site-directed irreversible inhibition of glutathione S-transferases by the glutathione conjugate of tetrachloro-1,4-benzoquinone by van Ommen, B, den Besten, C, Rutten, A L, Ploemen, J H, Vos, R M, Müller, F, van Bladeren, P J

“…Purified glutathione S-transferase from rat liver cytosol are irreversibly inhibited by the glutathione conjugate of tetrachloro-1,4-benzoquinone,…”
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Body fat distribution and the prognosis for weight reduction: preliminary observations by Vansant, G, Den Besten, C, Weststrate, J, Deurenberg, P

“…In a preliminary study the influence of body fat distribution on the degree of weight reduction, blood lipids and blood glucose was investigated in 17…”
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Cytochrome P450-Catalyzed Oxidation of Halobenzene Derivatives by Rietjens, Ivonne M. C. M, den Besten, Cathaline, Hanzlik, Robert P, van Bladeren, Peter J

“…Halogenated benzenes, considered relatively harmless because of their chemical stability, are thought to be bioactivated to products ultimately responsible for…”
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Preferred outcome measures in treatments for challenging behaviour in individuals with intellectual disabilities: Results of an inclusive Delphi method by Kuijper, Gerda M., Den Besten‐van Ravenswaaij, Janneke J. C., Hoekstra, Pieter J., Bildt, Annelies

“…Background Interventions for challenging behaviours in individuals with intellectual disabilities benefit from outcome monitoring that takes clients'…”
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Stability, Survival, and Tolerability of an Auditory Osseointegrated Implant for Bone Conduction Hearing: Long-Term Follow-Up of a Randomized Controlled Trial by den Besten, Christine A, Stalfors, Joacim, Wigren, Stina, Blechert, Johan Ivarsson, Flynn, Mark, Eeg-Olofsson, Måns, Aggarwal, Rohini, Green, Kevin, Nelissen, Rik C, Mylanus, Emmanuel A M, Hol, Myrthe K S

“…OBJECTIVE:To compare implant stability, survival, and soft tissue reactions for a novel (test) and previous generation (control) percutaneous auditory…”
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Cytochrome P450-mediated oxidation of pentafluorophenol to tetrafluorobenzoquinone as the primary reaction product by den Besten, Cathaline, van Bladeren, Peter J, Duizer, Erwin, Vervoort, Jacques, Rietjens, Ivonne M. C. M

“…In the present study the oxidative dehalogenation of a para-halogenated phenol was studied using pentafluorophenol and its non-para-halogenated analogue…”
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G.P.107: Complementary human skin models as a tool to study oligonucleotide-induced injection site reactions by den Besten, C., Steevels, T., Ekhart, P., Jones, S., Gibbs, S., Campion, G.

“…Injection site reactions (ISR) are commonly reported following subcutaneous (SC) administration of oligonucleotides (ONs). Development of ISRs following SC…”
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G.P.108: Transient proteinuria with oligonucleotide therapy due to interference with tubular protein reabsorption by den Besten, C., Jones, S., Wilmer, M., Masereeuw, R., Campion, G.

“…Prosensa Therapeutics is developing 2′O-modified phosphorothioate antisense oligonucleotides (AONs) to provide a mutation-specific therapy in the treatment of…”
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Immune Effects of Hexachlorobenzene in the Rat: Role of Metabolism in a 13-Week Feeding Study by Schielen, P., Denbesten, C., Vos, J.G., Vanbladeren, P.J., Seinen, W., Bloksma, N.

“…The role of metabolism and porphyria in the immunomodulating effects of hexachlorobenzene (HCB) was investigated. To this end, female Wistar rats received a…”
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High throughput screening of Pd-alloys for H 2 separation membranes studied by hydrogenography and CVM by Westerwaal, R.J., den Besten, C., Slaman, M., Dam, B., Nanu, D.E., Böttger, A.J., Haije, W.G.

“…The search for and development of stable Pd-based membranes for hydrogen separation applications with resistance to hydrogen embrittlement and cracking is a…”
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Comparative biotransformation of hexachlorobenzene and hexafluorobenzene in relation to the induction of porphyria by Rietjens, Ivonne M.C.M., Steensma, Aukje, Den Besten, Cathaline, van Tintelen, Gerrit, Haas, Jo, van Ommen, Ben, van Bladeren, Peter J.

“…The porphyrinogenic action of hexafluorobenzene was investigated and compared to that of hexachlorobenzene. Metabolite patterns in the urine of exposed rats…”
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The involvement of primary and secondary metabolism in the covalent binding of 1,2- and 1,4-dichlorobenzenes by den Besten, C, Ellenbroek, M, van der Ree, M A, Rietjens, I M, van Bladeren, P J

“…The microsomal oxidation of 1,2-[14C]- and 1,4-[14C]dichlorobenzene (DICB) was investigated with special attention for possible differences in…”
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Metabolic activation of 1,2,4-trichlorobenzene and pentachlorobenzene by rat liver microsomes: a major role for quinone metabolites by den Besten, C, Smink, M C, de Vries, E J, van Bladeren, P J

“…Microsomal metabolism of 1,2,4-[14C]trichlorobenzene (1,2,4-TrCB) and [14C]pentachlorobenzene (PeCB) was studied with special emphasis on the…”
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The metabolism of pentachlorobenzene by rat liver microsomes: the nature of the reactive intermediates formed by den Besten, C, Peters, M M, van Bladeren, P J

“…Metabolism of [14C]-pentachlorobenzene by liver microsomes from dexamethasone-induced rats results in the formation of pentachlorophenol and…”
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