Search Results - "den Bakker, M A"

Circulating endothelial cells in oncology: pitfalls and promises by Strijbos, M H, Gratama, J W, Kraan, J, Lamers, C H, Bakker, MA den, Sleijfer, S

“…Adequate blood supply is a prerequisite in the pathogenesis of solid malignancies. As a result, depriving a tumour from its oxygen and nutrients, either by…”
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Fatal outcome of a hypersensitivity reaction to paclitaxel: a critical review of premedication regimens by KLOOVER, J. S, DEN BAKKER, M. A, GELDERBLOM, H, VAN MEERBEECK, J. P

“…Hypersensitivity reactions (HSRs) to paclitaxel are frequently encountered in patients receiving this antitumour drug. Administration of histamine H1- and…”
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Lack of c-kit exon 11 activating mutations in c-KIT/CD117-positive SCLC tumour specimens by Burger, H., den Bakker, M.A., Stoter, G., Verweij, J., Nooter, K.

“…Previous studies have shown that STI571, a selective tyrosine kinase inhibitor of c-KIT, is highly effective in c-KIT/CD117-positive gastrointestinal stromal…”
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Non-sentinel lymph node involvement in patients with breast cancer and sentinel node micrometastasis; too early to abandon axillary clearance by den Bakker, M A, van Weeszenberg, A, de Kanter, A Y, Beverdam, F H, Pritchard, C, van der Kwast, Th H, Menke-Pluymers, M

“…Aims: It has been suggested that patients with T1–2 breast tumours and sentinel node (SLN) micrometastases, defined as foci of tumour cells smaller than 2 mm,…”
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A critical appraisal of prognostic and predictive factors for common lung cancers by Thunnissen, F B J M, Schuurbiers, O C J, Den Bakker, M A

“…The outlook for patients with lung cancer remains poor despite advances in the understanding of the pathology and biology of this disease. To optimize…”
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Interobserver variation in the classification of thymic tumours - a multicentre study using the WHO classification system by Verghese, E T, Den Bakker, M A, Campbell, A, Hussein, A, Nicholson, A G, Rice, A, Corrin, B, Rassl, D, Langman, G, Monaghan, H, Gosney, J, Seet, J, Kerr, K, Suvarna, S K, Burke, M, Bishop, P, Pomplun, S, Willemsen, S, Addis, B

“…Aims:  To test the reproducibility of the current World Health Organization (WHO) classification of thymic epithelial tumours and to determine the level of…”
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Malignant mesenchymoma of the uterus, arising in a leiomyoma by Bakker, M A den, Hegt, V Noordhoek, Sleddens, H B F M, Nuijten, A S M, Dinjens, W N M

“…Malignant mesenchymoma of the uterus, arising in a leiomyoma Aims: To document and find evidence for the rare occurrence of malignant progression of a benign…”
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CD31 staining in epithelioid sarcoma by DEN BAKKER, M. A, FLOOD, S. J, KLIFFEN, M

“…We report an unusual case of epithelioid sarcoma. The tumour occurred in the finger of a 27-year-old female. The clinical history, histology and the electron…”
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Outcomes of First-Line Chemotherapy in Patients with Advanced or Metastatic Leiomyosarcoma of Uterine and Non-Uterine Origin by Oosten, A. W., Seynaeve, C., Schmitz, P. I. M., den Bakker, M. A., Verweij, J., Sleijfer, S.

“…Although leiomyosarcomas (LMSs) form the largest subgroup of soft tissue sarcomas (STSs), the efficacy of chemotherapy in this group is largely unclear, partly…”
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Classifying thymomas by Addis, B J, Den Bakker, M A

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DLL3 expression in large cell neuroendocrine carcinoma (LCNEC) and association with molecular subtypes and neuroendocrine profile by Hermans, B.C.M., Derks, J.L., Thunnissen, E., van Suylen, R.J., den Bakker, M.A., Groen, H.J.M., Smit, E.F., Damhuis, R.A., van den Broek, E.C., Ruland, A., Speel, E.J.M., Dingemans, A.M.C.

“…•DLL3 is expressed in 74% of stage IV LCNEC patients•The majority (80%) has cytoplasmic/membranous expression•DLL3 is expressed in both SCLC- and NSCLC-like…”
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Prevalence and prognostic value of PD-L1 expression in molecular subtypes of metastatic large cell neuroendocrine carcinoma (LCNEC) by Hermans, B.C.M., Derks, J.L., Thunnissen, E., van Suylen, R.J., den Bakker, M.A., Groen, H.J.M., Smit, E.F., Damhuis, R.A., van den Broek, E.C., Stallinga, C.M., Roemen, G.M., Speel, E.J.M., Dingemans, A.-M.C.

“…•PD-L1 ≥ 1% is expressed in 16% of stage IV LCNEC, 5% has expression ≥50%.•PD-L1 staining in LCNEC is comparable to values in SCLC, but lower than in NSCLC.•No…”
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Molecular analysis of human endometrium : short-term tibolone signaling differs significantly from estrogen and estrogen + progestagen signaling by HANIFI-MOGHADDAM, P, BOERS-SIJMONS, B, BLOK, L. J, KLAASSENS, A. H. A, VAN WIJK, F. H, DEN BAKKER, M. A, OTT, M. C, SHIPLEY, G. L, VERHEUL, H. A. M, KLOOSTERBOER, H. J, BURGER, C. W

“…Tibolone, a tissue-selective compound with a combination of estrogenic, progestagenic, and androgenic properties, is used as an alternative for estrogen or…”
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Neuroendocrine tumours--challenges in the diagnosis and classification of pulmonary neuroendocrine tumours by den Bakker, M A, Thunnissen, F B J M

“…Pulmonary neuroendocrine (NE) proliferations are a diverse group of disorders which share distinct cytological, architectural and biosynthetic features…”
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“Cutaneous-type” angiosarcoma arising in a mature cystic teratoma of the ovary by den Bakker, M A, Ansink, A C, Ewing-Graham, P C

“…Benign and malignant somatic tumours arising in mature cystic teratomas of the ovary are a rare but recognised phenomenon. Squamous cell carcinoma is the most…”
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A new approach for rapid and reliable enumeration of circulating endothelial cells in patients by KRAAN, J., STRIJBOS, M. H., SIEUWERTS, A. M., FOEKENS, J. A., DEN BAKKER, M. A., VERHOEF, C., SLEIJFER, S., GRATAMA, J. W.

“…Background:  Mature circulating endothelial cells (CECs) are surrogate markers of endothelial damage/dysfunction. A lack of standardized assays and consensus…”
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Implications of frozen section analyses from bronchial resection margins in NSCLC by Thunnissen, F B J M, Den Bakker, M A

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Cardiac myxoma with atypical glandular component, report of a case by Den Bakker, M A, Dinjens, W N M, Bekkers, J A

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Neurofibromatosis type 2 protein co-localizes with elements of the cytoskeleton by den Bakker, MA, Tascilar, M, Riegman, PH, Hekman, AC, Boersma, W, Janssen, PJ, de Jong, TA, Hendriks, W, van der Kwast, TH, Zwarthoff, EC

“…The product of the neurofibromatosis type 2 (NF2) tumor suppressor gene is a 595-amino-acid protein bearing resemblance to a family of band-4.1-related…”
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Microsatellite instability in a pleomorphic rhabdomyosarcoma in a patient with hereditary non-polyposis colorectal cancer by Den Bakker, M A, Seynaeve, C, Kliffen, M, Dinjens, W N M

“…Aims:  To describe the rare occurrence of a pleomorphic sarcoma with microsatellite instability in a patient with hereditary non‐polyposis colorectal cancer…”
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