Search Results - "del Real, Alvaro"

Analysis of Bone Histomorphometry in Rat and Guinea Pig Animal Models Subject to Hypoxia by Usategui-Martín, Ricardo, Del Real, Álvaro, Sainz-Aja, José A., Prieto-Lloret, Jesús, Olea, Elena, Rocher, Asunción, Rigual, Ricardo J., Riancho, José A., Pérez-Castrillón, José Luis

“…Hypoxia may be associated with alterations in bone remodeling, but the published results are contradictory. The aim of this study was to characterize the bone…”
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Epigenetic Aging in Osteoporosis by del Real, Alvaro, Riancho‐Zarrabeitia, Leyre, Riancho, Jose A

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Differential analysis of genome-wide methylation and gene expression in mesenchymal stem cells of patients with fractures and osteoarthritis by del Real, Alvaro, Pérez-Campo, Flor M., Fernández, Agustín F., Sañudo, Carolina, Ibarbia, Carmen G., Pérez-Núñez, María I., Criekinge, Wim Van, Braspenning, Maarten, Alonso, María A., Fraga, Mario F., Riancho, Jose A.

“…Insufficient activity of the bone-forming osteoblasts leads to low bone mass and predisposes to fragility fractures. The functional capacity of human…”
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High Frequencies of Genetic Variants in Patients with Atypical Femoral Fractures by Del Real, Álvaro, Cruz, Raquel, Sañudo, Carolina, Pérez-Castrillón, José L, Pérez-Núñez, María I, Olmos, Jose M, Hernández, José L, García-Ibarbia, Carmen, Valero, Carmen, Riancho, Jose A

“…This study explores the genetic factors associated with atypical femoral fractures (AFF), rare fractures associated with prolonged anti-resorptive therapy. AFF…”
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A Missense Variant in TP53 Could Be a Genetic Biomarker Associated with Bone Tissue Alterations by Usategui-Martín, Ricardo, Galindo-Cabello, Nadia, Pastor-Idoate, Salvador, Fernández-Gómez, José María, Del Real, Álvaro, Ferreño, Diego, Lapresa, Rebeca, Martín-Rodriguez, Francisco, Riancho, José A, Almeida, Ángeles, Pérez-Castrillón, José Luis

“…Metabolic bone diseases cover a broad spectrum of disorders that share alterations in bone metabolism that lead to a defective skeleton, which is associated…”
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Pharmacogenetics of Osteoporosis: A Pathway Analysis of the Genetic Influence on the Effects of Antiresorptive Drugs by Del Real, Álvaro, Valero, Carmen, Olmos, José M, Hernández, Jose L, Riancho, José A

“…Osteoporosis is a skeletal disorder defined by a decreased bone mineral density (BMD) and an increased susceptibility to fractures. Bisphosphonates and…”
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Osteomesopyknosis associated with a novel ALOX5 variant that impacts the RANKL pathway by Fernandez‐Luna, Jose L., Hernández, José L., Curiel‐Olmo, Soraya, Martínez‐Amador, Néstor A., Vega, Ana I., Quirce, Remedios, Montes‐Moreno, Santiago, Gutierrez, Olga, Real, Alvaro, Sañudo, Carolina, Riancho, Jose A.

“…Background Bone tissue homeostasis relies on the coordinated activity of the bone‐forming osteoblasts and bone‐resorbing osteoclasts. Osteomesopyknosis is…”
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Association Between Suicide and Environmental Variables in the North of Spain: A 14-Year Analysis by Santurtún, Maite, Sanchez-Lorenzo, Arturo, del Real, Álvaro, Zarrabeitia, María T., Santurtún, Ana

“…Suicide is a serious public health problem around the world. Since the nineteenth century, the impact of socio-environmental factors on suicide has attracted…”
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Analysis of Serum Proteome after Treatment of Osteoporosis with Anabolic or Antiresorptive Drugs by Del Real, Alvaro, Ciordia, Sergio, Sañudo, Carolina, Garcia-Ibarbia, Carmen, Roa-Bautista, Adriel, Ocejo-Viñals, Javier G, Corrales, Fernando, Riancho, Jose A

“…The aim of the study was to explore new markers in serum proteome associated with the response to antiosteoporosis drugs, namely teriparatide and denosumab. We…”
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Hyperbaric Oxygen Therapy Does Not Have a Negative Impact on Bone Signaling Pathways in Humans by Salmón-González, Zaida, Anchuelo, Javier, Borregán, Juan C, Del Real, Alvaro, Sañudo, Carolina, García-Unzueta, Maria Teresa, Riancho, José A, Valero, Carmen

“…Oxygen is emerging as an important factor in the local regulation of bone remodeling. Some preclinical data suggest that hyperoxia may have deleterious effects…”
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Age-associated hydroxymethylation in human bone-marrow mesenchymal stem cells by Toraño, Estela G, Bayón, Gustavo F, Del Real, Álvaro, Sierra, Marta I, García, María G, Carella, Antonella, Belmonte, Thalia, Urdinguio, Rocío G, Cubillo, Isabel, García-Castro, Javier, Delgado-Calle, Jesús, Pérez-Campo, Flor M, Riancho, José A, Fraga, Mario F, Fernández, Agustín F

“…Age-associated changes in genomic DNA methylation have been primarily attributed to 5-methylcytosine (5mC). However, the recent discovery of…”
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Polygenic risk of bone fractures in Spanish women with osteoporosis by del Real, Álvaro, Cruz, Raquel, Olmos Martínez, José Manuel, Hernández, José L., Valero Díaz de la Madrid, Carmen, Riancho Moral, José Antonio

“…Abstract Background: osteoporosis is a highly polygenic trait characterized by low bone mineral density (BMD) and/or fragility fractures. Over the past decade,…”
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Epigenetic related changes on air quality by Real, Álvaro del, Santurtún, Ana, Teresa Zarrabeitia, M.

“…The exposure to airborne particulate matter (PM) increases the risk of developing human diseases. Epigenetic mechanisms have been related to environmental…”
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Exposure to particulate matter: Direct and indirect role in the COVID-19 pandemic by Santurtún, Ana, Colom, Marina L., Fdez-Arroyabe, Pablo, Real, Álvaro del, Fernández-Olmo, Ignacio, Zarrabeitia, María T.

“…Knowing the transmission factors and the natural environment that favor the spread of a viral infection is crucial to stop outbreaks and develop effective…”
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The impact of genetic variations in the serotonergic system on symptom severity and clinical outcome in functional neurological disorders by Weber, Samantha, Rey Álvarez, Lucía Trinidad, Ansede-Bermejo, Juan, Cruz, Raquel, del Real, Álvaro, Bühler, Janine, Carracedo, Ángel, Aybek, Selma

“…We studied gene-environment, as well as gene-gene interaction to elucidate their effects on symptom severity and predict clinical outcomes in functional…”
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SARS-CoV-2 surveillance in indoor and outdoor size-segregated aerosol samples by del Real, Álvaro, Expósito, Andrea, Ruiz-Azcona, Laura, Santibáñez, Miguel, Fernández-Olmo, Ignacio

“…We aimed to determine the presence of SARS-CoV-2 RNA in indoor and outdoor size-segregated aerosol samples (PM 10-2.5 , PM 2.5 ). Five outdoor daily samples…”
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Forensic databases, a perspective from the penitentiary centers of Spain by del Real, Álvaro, Sáenz-Aldea, María, Santurtún, Ana, Zarrabeitia, María T.

“…•Most prisoners and officials consider the national forensic database to be useful.•Suspects identification through “familial searching” is considered…”
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Specific premature epigenetic aging of cartilage in osteoarthritis by Vidal-Bralo, Laura, Lopez-Golan, Yolanda, Mera-Varela, Antonio, Rego-Perez, Ignacio, Horvath, Steve, Zhang, Yuhua, Del Real, Álvaro, Zhai, Guangju, Blanco, Francisco J, Riancho, Jose A, Gomez-Reino, Juan J, Gonzalez, Antonio

“…Osteoarthritis (OA) is a disease affecting multiple tissues of the joints in the elderly, but most notably articular cartilage. Premature biological aging has…”
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Effects of Systemic or Local Administration of Mesenchymal Stem Cells from Patients with Osteoporosis or Osteoarthritis on Femoral Fracture Healing in a Mouse Model by Laguna, Esther, Pérez-Núñez, María Isabel, Del Real, Álvaro, Menéndez, Guillermo, Sáinz-Aja, José A, López-Delgado, Laura, Sañudo, Carolina, Martín, Alicia, Mazorra, Remigio, Ferreño, Diego, García-Montesinos, Belén, Riancho, José A

“…The purpose of this study was to analyze the regenerative capacity of mesenchymal stem cells (MSCs) in the treatment of fractures. MSCs extracted from patients…”
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Lycopene overproduction and in situ extraction in organic-aqueous culture systems using a metabolically engineered Escherichia coli by Gallego-Jara, Julia, de Diego, Teresa, del Real, Álvaro, Écija-Conesa, Ana, Manjón, Arturo, Cánovas, Manuel

“…Lycopene is an import ant compound with an increasing industrial value. However, there is still no biotechnological process to obtain it. In this study, a…”
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