Search Results - "del Olmo, María L."

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    AZT induces oxidative damage to cardiac mitochondria: Protective effect of vitamins C and E by García de la Asunción, José, L. del Olmo, María, Gómez-Cambronero, Luis G., Sastre, Juan, Pallardó, Federico V., Viña, José

    Published in Life sciences (1973) (19-11-2004)
    “…AZT (zidovudine) is a potent inhibitor of HIV replication and a major antiretroviral drug used for AIDS treatment. A major limitation in the use of AZT is the…”
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  2. 2

    Zidovudine (AZT) causes an oxidation of mitochondrial DNA in mouse liver by García de la Asunción, José, del Olmo, María L., Sastre, Juan, Pallardó, Federico V., Viña, José

    Published in Hepatology (Baltimore, Md.) (01-03-1999)
    “…Zidovudine (3′‐azido‐2′,3′‐dideoxythymidine [AZT]) inhibits human immunodeficiency virus replication and delays progression of acquired immune deficiency…”
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    AZT treatment induces molecular and ultrastructural oxidative damage to muscle mitochondria. Prevention by antioxidant vitamins by de la Asunción, J G, del Olmo, M L, Sastre, J, Millán, A, Pellín, A, Pallardó, F V, Viña, J

    Published in The Journal of clinical investigation (01-07-1998)
    “…AIDS patients who receive zidovudine (AZT) frequently suffer from myopathy. This has been attributed to mitochondrial (mt) damage, and specifically to the loss…”
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    Journal Article