Search Results - "del Olmo, María L."
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AZT induces oxidative damage to cardiac mitochondria: Protective effect of vitamins C and E
Published in Life sciences (1973) (19-11-2004)“…AZT (zidovudine) is a potent inhibitor of HIV replication and a major antiretroviral drug used for AIDS treatment. A major limitation in the use of AZT is the…”
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Zidovudine (AZT) causes an oxidation of mitochondrial DNA in mouse liver
Published in Hepatology (Baltimore, Md.) (01-03-1999)“…Zidovudine (3′‐azido‐2′,3′‐dideoxythymidine [AZT]) inhibits human immunodeficiency virus replication and delays progression of acquired immune deficiency…”
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AZT treatment induces molecular and ultrastructural oxidative damage to muscle mitochondria. Prevention by antioxidant vitamins
Published in The Journal of clinical investigation (01-07-1998)“…AIDS patients who receive zidovudine (AZT) frequently suffer from myopathy. This has been attributed to mitochondrial (mt) damage, and specifically to the loss…”
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