Search Results - "deBoer, Johan G."

Frequency and spectrum of ethylnitrosourea-induced mutation at the hprt and lacI loci in splenic lymphocytes of exposed lacI transgenic mice by WALKER, V. E, GORELICK, N. J, ANDREWS, J. L, CRAFT, T. R, DEBOER, J. G, GLICKMAN, B. W, SKOPEK, T. R

“…The development of mouse models with the endogenous hypoxanthine-guanine phosphoribosyl transferase (hprt) gene and lacI transgene as mutational targets…”
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Tissue-specific mutant frequencies and mutational spectra in cyclophosphamide-treatedlacI transgenic mice by Gorelick, Nancy J., Andrews, Julie L., deBoer, Johan G., Young, Robert, Gibson, David P., Walker, Vernon E.

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Detection of cyclophosphamide-induced mutations at theHprt but not thelacI locus in splenic lymphocytes of exposed mice by Walker, Vernon E., Andrews, Julie L., Upton, Patricia B., Skopek, Thomas R., deBoer, Johan G., Walker, Dale M., Shi, Xiaochu, Sussman, Hillary E., Gorelick, Nancy J.

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Tissue-specific mutant frequencies and mutational spectra in cyclophosphamide-treated lacI transgenic mice by Gorelick, Nancy J., Andrews, Julie L., deBoer, Johan G., Young, Robert, Gibson, David P., Walker, Vernon E.

“…The induction and nature of mutations in the lacI transgene were evaluated in multiple tissues after exposure of adult male B6C3F1 lacI transgenic mice to…”
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Detection of cyclophosphamide-induced mutations at the Hprt but not the lacI locus in splenic lymphocytes of exposed mice by Walker, Vernon E., Andrews, Julie L., Upton, Patricia B., Skopek, Thomas R., deBoer, Johan G., Walker, Dale M., Shi, Xiaochu, Sussman, Hillary E., Gorelick, Nancy J.

“…The relative sensitivities and specificities of the endogenous Hprt gene and the lacI transgene as mutational targets were evaluated in splenic lymphocytes…”
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Hotspot sites for acridine-induced frameshift mutations in bacteriophage T4 correspond to sites of action of the T4 type II topoisomerase by Ripley, L S, Dubins, J S, deBoer, J G, DeMarini, D M, Bogerd, A M, Kreuzer, K N

“…The type II topoisomerase of bacteriophage T4 is a central determinant of the frequency and specificity of acridine-induced frameshift mutations…”
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