Search Results - "de los Fayos Alonso, Ines Garces"
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The Role of Activator Protein-1 (AP-1) Family Members in CD30-Positive Lymphomas
Published in Cancers (28-03-2018)“…The Activator Protein-1 (AP-1) transcription factor (TF) family, composed of a variety of members including c-JUN, c-FOS and ATF, is involved in mediating many…”
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KMT2C methyltransferase domain regulated INK4A expression suppresses prostate cancer metastasis
Published in Molecular cancer (30-03-2022)“…Frequent truncation mutations of the histone lysine N-methyltransferase KMT2C have been detected by whole exome sequencing studies in various cancers,…”
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The targetable kinase PIM1 drives ALK inhibitor resistance in high-risk neuroblastoma independent of MYCN status
Published in Nature communications (28-11-2019)“…Resistance to anaplastic lymphoma kinase (ALK)-targeted therapy in ALK-positive non-small cell lung cancer has been reported, with the majority of acquired…”
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Blocking STAT3/5 through direct or upstream kinase targeting in leukemic cutaneous T‐cell lymphoma
Published in EMBO molecular medicine (07-12-2022)“…Leukemic cutaneous T‐cell lymphomas (L‐CTCL) are lymphoproliferative disorders of skin‐homing mature T‐cells causing severe symptoms and high mortality through…”
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JUN mediates the senescence associated secretory phenotype and immune cell recruitment to prevent prostate cancer progression
Published in Molecular cancer (29-05-2024)“…Prostate cancer develops through malignant transformation of the prostate epithelium in a stepwise, mutation-driven process. Although activator protein-1…”
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Distinct Subtypes of Chemotherapy-Resistant Systemic ALK-Positive Anaplastic Large Cell Lymphoma Demonstrate Long-Term Complete Remissions to Imatinib
Published in Blood (02-11-2023)“…Background Platelet-derived growth factor receptor (PDGFR) is expressed in nucleophosmin-anaplastic lymphoma kinase (NPM-ALK) positive anaplastic large cell…”
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Imatinib +/- Brentuximab Vedotin Induces Sustained Complete Remission in Chemotherapy-Resistant Anaplastic Large Cell Lymphoma Expressing PDGFR
Published in Blood (13-11-2019)“…Background. Anaplastic lymphoma kinase positive systemic anaplastic large cell lymphoma (ALK+ ALCL) represents an aggressive T-cell malignancy that primarily…”
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