Search Results - "de la Vega, Montserrat Rojo"

Kelch-like ECH-associated protein 1 (KEAP1) differentially regulates nuclear factor erythroid-2–related factors 1 and 2 (NRF1 and NRF2) by Tian, Wang, Rojo de la Vega, Montserrat, Schmidlin, Cody J., Ooi, Aikseng, Zhang, Donna D.

“…Nuclear factor erythroid-2–related factor 1 (NRF1) and NRF2 are essential for maintaining redox homeostasis and coordinating cellular stress responses. They…”
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Molecular mechanisms of Nrf2 regulation and how these influence chemical modulation for disease intervention by Harder, Bryan, Jiang, Tao, Wu, Tongde, Tao, Shasha, Rojo de la Vega, Montserrat, Tian, Wang, Chapman, Eli, Zhang, Donna D

“…Nrf2 (nuclear factor erytheroid-derived-2-like 2) transcriptional programmes are activated by a variety of cellular stress conditions to maintain cellular…”
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An Essential Role of NRF2 in Diabetic Wound Healing by Long, Min, Rojo de la Vega, Montserrat, Wen, Qing, Bharara, Manish, Jiang, Tao, Zhang, Rui, Zhou, Shiwen, Wong, Pak K, Wondrak, Georg T, Zheng, Hongting, Zhang, Donna D

“…The high mortality and disability of diabetic nonhealing skin ulcers create an urgent need for the development of more efficacious strategies targeting…”
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The effects of NRF2 modulation on the initiation and progression of chemically and genetically induced lung cancer by Tao, Shasha, Rojo de la Vega, Montserrat, Chapman, Eli, Ooi, Aikseng, Zhang, Donna D.

“…Targeting the transcription factor NRF2 has been recognized as a feasible strategy for cancer prevention and treatment, but many of the mechanistic details…”
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NRF2 activation by antioxidant antidiabetic agents accelerates tumor metastasis by Wang, Hui, Liu, Xiufei, Long, Min, Huang, Yi, Zhang, Linlin, Zhang, Rui, Zheng, Yi, Liao, Xiaoyu, Wang, Yuren, Liao, Qian, Li, Wenjie, Tang, Zili, Tong, Qiang, Wang, Xiaocui, Fang, Fang, Rojo de la Vega, Montserrat, Ouyang, Qin, Zhang, Donna D, Yu, Shicang, Zheng, Hongting

“…Cancer is a common comorbidity of diabetic patients; however, little is known about the effects that antidiabetic drugs have on tumors. We discovered that…”
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NRF2 Induction for NASH Treatment: A New Hope Rises by Rojo de la Vega, Montserrat, MSc, Zhang, Donna D., PhD

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RPA1 binding to NRF2 switches ARE-dependent transcriptional activation to ARE-NRE–dependent repression by Liu, Pengfei, de la Vega, Montserrat Rojo, Sammani, Saad, Mascarenhas, Joseph B., Kerins, Michael, Dodson, Matthew, Sun, Xiaoguang, Wang, Ting, Ooi, Aikseng, Garcia, Joe G. N., Zhang, Donna D.

“…NRF2 regulates cellular redox homeostasis, metabolic balance, and proteostasis by forming a dimer with small musculoaponeurotic fibrosarcoma proteins (sMAFs)…”
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Bixin protects mice against ventilation-induced lung injury in an NRF2-dependent manner by Tao, Shasha, Rojo de la Vega, Montserrat, Quijada, Hector, Wondrak, Georg T., Wang, Ting, Garcia, Joe G. N., Zhang, Donna D.

“…Mechanical ventilation (MV) is a therapeutic intervention widely used in the clinic to assist patients that have difficulty breathing due to lung edema,…”
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Topical Bixin Confers NRF2-Dependent Protection Against Photodamage and Hair Graying in Mouse Skin by Rojo de la Vega, Montserrat, Zhang, Donna D, Wondrak, Georg T

“…Environmental exposure to solar ultraviolet (UV) radiation causes acute photodamage, premature aging, and skin cancer, attributable to UV-induced genotoxic,…”
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Targeting NRF2 for Improved Skin Barrier Function and Photoprotection: Focus on the Achiote-Derived Apocarotenoid Bixin by Rojo de la Vega, Montserrat, Krajisnik, Andrea, Zhang, Donna D, Wondrak, Georg T

“…The transcription factor NRF2 (nuclear factor-E2-related factor 2) orchestrates major cellular defense mechanisms including phase-II detoxification,…”
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Nrf2-dependent suppression of azoxymethane/dextran sulfate sodium-induced colon carcinogenesis by the cinnamon-derived dietary factor cinnamaldehyde by Long, Min, Tao, Shasha, Rojo de la Vega, Montserrat, Jiang, Tao, Wen, Qing, Park, Sophia L, Zhang, Donna D, Wondrak, Georg T

“…The progressive nature of colorectal cancer and poor prognosis associated with the metastatic phase of the disease create an urgent need for the development of…”
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The antimalarial amodiaquine causes autophagic-lysosomal and proliferative blockade sensitizing human melanoma cells to starvation- and chemotherapy-induced cell death by Qiao, Shuxi, Tao, Shasha, Rojo de la Vega, Montserrat, Park, Sophia L, Vonderfecht, Amanda A, Jacobs, Suesan L, Zhang, Donna D, Wondrak, Georg T

“…Pharmacological inhibition of autophagic-lysosomal function has recently emerged as a promising strategy for chemotherapeutic intervention targeting cancer…”
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NRF2 and the Hallmarks of Cancer by Rojo de la Vega, Montserrat, Chapman, Eli, Zhang, Donna D.

“…The transcription factor NRF2 is the master regulator of the cellular antioxidant response. Though recognized originally as a target of chemopreventive…”
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ABCF2, an Nrf2 target gene, contributes to cisplatin resistance in ovarian cancer cells by Bao, Lingjie, Wu, Jianfa, Dodson, Matthew, Rojo de la Vega, Elisa Montserrat, Ning, Yan, Zhang, Zhenbo, Yao, Ming, Zhang, Donna D., Xu, Congjian, Yi, Xiaofang

“…Previously, we have demonstrated that NRF2 plays a key role in mediating cisplatin resistance in ovarian cancer. To further explore the mechanism underlying…”
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Activation of NRF2 by topical apocarotenoid treatment mitigates radiation-induced dermatitis by Schmidlin, Cody J., Rojo de la Vega, Montserrat, Perer, Jessica, Zhang, Donna D., Wondrak, Georg T.

“…Radiation therapy is a frontline treatment option for cancer patients; however, the effects of radiotherapy on non-tumor tissue (e.g. radiation-induced…”
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Role of Nrf2 and Autophagy in Acute Lung Injury by de la Vega, Montserrat Rojo, Dodson, Matthew, Gross, Christine, Mansour, Heidi M., Lantz, R. Clark, Chapman, Eli, Wang, Ting, Black, Stephen M., Garcia, Joe G. N., Zhang, Donna D.

“…Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) are the clinical manifestations of severe lung damage and respiratory failure…”
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p62 links autophagy and Nrf2 signaling by Jiang, Tao, Harder, Bryan, Rojo de la Vega, Montserrat, Wong, Pak K., Chapman, Eli, Zhang, Donna D.

“…The Nrf2-Keap1-ARE pathway is a redox and xenobiotic sensitive signaling axis that functions to protect cells against oxidative stress, environmental…”
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NRF2-targeted therapeutics: New targets and modes of NRF2 regulation by Rojo de la Vega, Montserrat, Dodson, Matthew, Chapman, Eli, Zhang, Donna D.

“…Pharmacological activation of the transcription factor nuclear factor-erythroid derived 2-like 2 (NRF2), the key regulator of the cellular antioxidant…”
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A holistic view of cancer by Rojo de la Vega, Montserrat

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Modulating NRF2 in Disease: Timing Is Everything by Dodson, Matthew, de la Vega, Montserrat Rojo, Cholanians, Aram B, Schmidlin, Cody J, Chapman, Eli, Zhang, Donna D

“…The transcription factor nuclear factor erythroid 2 (NF-E2)-related factor 2 (NRF2) is a central regulator of redox, metabolic, and protein homeostasis that…”
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