Search Results - "de la Rocha, Carmen"
-
1
The DNA methyltransferase inhibitor decitabine blunts the response to a high-animal fat and protein diet in mice
Published in Journal of lipid research (01-08-2024)“…Increasing evidence hints that DNA hypermethylation may mediate the pathogenic response to cardiovascular risk factors. Here, we tested a corollary of that…”
Get full text
Journal Article -
2
The DNA methylation drift of the atherosclerotic aorta increases with lesion progression
Published in BMC medical genomics (27-02-2015)“…Atherosclerosis severity-independent alterations in DNA methylation, a reversible and highly regulated DNA modification, have been detected in aortic…”
Get full text
Journal Article -
3
Associations between whole peripheral blood fatty acids and DNA methylation in humans
Published in Scientific reports (16-05-2016)“…Fatty acids (FA) modify DNA methylation in vitro , but limited information is available on whether corresponding associations exist in vivo and reflect any…”
Get full text
Journal Article -
4
Cumulative Metabolic and Epigenetic Effects of Paternal and/or Maternal Supplementation with Arachidonic Acid across Three Consecutive Generations in Mice
Published in Cells (Basel, Switzerland) (21-03-2022)“…Apart from the known associations between arachidonic acid (AA), weight gain, and neurological and immune function, AA exposure leads to alterations in global…”
Get full text
Journal Article -
5
Liver X Receptor–Binding DNA Motif Associated With Atherosclerosis‐Specific DNA Methylation Profiles of Alu Elements and Neighboring CpG Islands
Published in Journal of the American Heart Association (06-02-2018)“…Background The signals that determine atherosclerosis‐specific DNA methylation profiles are only partially known. We previously identified a 29‐bp DNA motif…”
Get full text
Journal Article -
6
Is Any Cardiovascular Disease-Specific DNA Methylation Biomarker Within Reach?
Published in Current atherosclerosis reports (26-08-2020)“…Purpose of Review A detailed understanding of the epigenome of cardiovascular disease (CVD) should broaden current insights into mechanisms of atherogenesis…”
Get full text
Journal Article -
7
Reprogramming transgenerational programming
Published in Current opinion in lipidology (01-12-2015)Get full text
Journal Article -
8
Modulatory L-Alliin Effect on Acute Inflammatory Cytokines in Diet-Induced Obesity Mice
Published in Metabolites (27-10-2024)“…Background/Objectives: The inflammatory response has evolved as a protective mechanism against pathogens and tissue damage. However, chronic inflammation can…”
Get full text
Journal Article -
9
Somatic Genetic Mosaicism in the Apolipoprotein E-null Mouse Aorta
Published in Thrombosis and haemostasis (01-11-2021)“…In addition to genetic and epigenetic inheritance, somatic variation may contribute to cardiovascular disease (CVD) risk. CVD-associated somatic mutations have…”
Get more information
Journal Article -
10
Effect of Arachidonic Acid Supplement in both Maternal and Paternal Line on Global DNA Methylation in Mice transgenerationally
Published in The FASEB journal (01-04-2016)“…Abstract only…”
Get full text
Journal Article -
11
Ivermectin compared with placebo in the clinical course in Mexican patients with asymptomatic and mild COVID-19: a randomized clinical trial
Published in BMC infectious diseases (08-12-2022)“…Despite the development and application of vaccines against Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) around the world, the scientific…”
Get full text
Journal Article -
12
Assessment of work-related stress and burnout among clinical research occupations [version 1; peer review: 1 approved with reservations]
Published in F1000 research (2023)“…Background: Burnout syndrome is included by the World Health Organization (WHO) in the International Classification of Diseases, and it has a direct impact on…”
Get full text
Journal Article