Search Results - "de la Motte, A"

Human intelectin-1 (ITLN1) genetic variation and intestinal expression by Nonnecke, Eric B., Castillo, Patricia A., Dugan, Amanda E., Almalki, Faisal, Underwood, Mark A., De La Motte, Carol A., Yuan, Weirong, Lu, Wuyuan, Shen, Bo, Johansson, Malin E. V., Kiessling, Laura L., Hollox, Edward J., Lönnerdal, Bo, Bevins, Charles L.

“…Intelectins are ancient carbohydrate binding proteins, spanning chordate evolution and implicated in multiple human diseases. Previous GWAS have linked SNPs in…”
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Molecular mass dependence of hyaluronan detection by sandwich ELISA-like assay and membrane blotting using biotinylated hyaluronan binding protein by Yuan, Han, Tank, Mihir, Alsofyani, Abeer, Shah, Naman, Talati, Nishant, LoBello, Jaclyn C, Kim, Jin Ryoun, Oonuki, Yoji, de la Motte, Carol A, Cowman, Mary K

“…Hyaluronan (HA) is widely detected in biological samples and its concentration is most commonly determined by the use of a labeled specific HA binding protein…”
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The Role of Hyaluronan Treatment in Intestinal Innate Host Defense by Kim, Yeojung, de la Motte, Carol A

“…Hyaluronan (HA) is best known as an abundantly present extracellular matrix component found throughout the body of all vertebrates, including humans. Recent…”
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Hyaluronan in intestinal homeostasis and inflammation: implications for fibrosis by de la Motte, Carol A

“…The causes of fibrosis, or the inappropriate wound healing, that follows chronic intestinal inflammation are not well defined and likely involve the…”
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Hyaluronan’s Role in Fibrosis: A Pathogenic Factor or a Passive Player? by Albeiroti, Sami, de la Motte, Carol A., Soroosh, Artin

“…Fibrosis is a debilitating condition that can lead to impairment of the affected organ’s function. Excessive deposition of extracellular matrix (ECM) molecules…”
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Characterization of hyaluronan cable structure and function in renal proximal tubular epithelial cells by Selbi, W., de la Motte, C.A., Hascall, V.C., Day, A.J., Bowen, T., Phillips, A.O.

“…Alteration in the glycosaminoglycan hyaluronan (HA) has been demonstrated in numerous renal diseases. We have demonstrated that renal proximal tubular…”
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Hyaluronan, a crucial regulator of inflammation by Petrey, Aaron C, de la Motte, Carol A

“…Hyaluronan (HA), a major component of the extracellular matrix (ECM), plays a key role in regulating inflammation. Inflammation is associated with accumulation…”
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Determination of hyaluronan molecular mass distribution in human breast milk by Yuan, Han, Amin, Ripal, Ye, Xin, de la Motte, Carol A., Cowman, Mary K.

“…Hyaluronan (HA) in human milk mediates host responses to microbial infection via TLR4- and CD44-dependent signaling. Signaling by HA is generally size…”
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Endoplasmic Reticulum Stress Induces Hyaluronan Deposition and Leukocyte Adhesion by Majors, Alana K., Austin, Richard C., de la Motte, Carol A., Pyeritz, Reed E., Hascall, Vincent C., Kessler, Sean P., Sen, Ganes, Strong, Scott A.

“…There is mounting evidence that perturbations in endoplasmic reticulum (ER) function play a key role in the pathogenesis of a broad range of diseases. We have…”
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The dietary polysaccharide maltodextrin promotes Salmonella survival and mucosal colonization in mice by Nickerson, Kourtney P, Homer, Craig R, Kessler, Sean P, Dixon, Laura J, Kabi, Amrita, Gordon, Ilyssa O, Johnson, Erin E, de la Motte, Carol A, McDonald, Christine

“…In the latter half of the 20th century, societal and technological changes led to a shift in the composition of the American diet to include a greater…”
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Specifically Sized Hyaluronan (35 kDa) Prevents Ethanol‐Induced Disruption of Epithelial Tight Junctions Through a layilin‐Dependent Mechanism in Caco‐2 Cells by Bellos, Damien A., Sharma, Dhara, McMullen, Megan R., Wat, Jeanette, Saikia, Paramananda, Motte, Carol A., Nagy, Laura E.

“…Background Specific‐sized species of the carbohydrate hyaluronan elicit a variety of cellular responses mediating tissue integrity and repair, as well as…”
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Mononuclear Leukocytes Preferentially Bind via CD44 to Hyaluronan on Human Intestinal Mucosal Smooth Muscle Cells after Virus Infection or Treatment with Poly(I·C) by de la Motte, Carol A., Hascall, Vincent C., Calabro, Anthony, Yen-Lieberman, Belinda, Strong, Scott A.

“…Pathological changes in inflammatory bowel disease include an increase in intestinal mucosal mononuclear leukocytes and hyperplasia of the muscularis mucosae…”
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Protective role of macrophage-derived ceruloplasmin in inflammatory bowel disease by Bakhautdin, Bakytzhan, Febbraio, Maria, Goksoy, Esen, de la Motte, Carol A, Gulen, Muhammet F, Childers, Erin Patricia, Hazen, Stanley L, Li, Xiaoxia, Fox, Paul L

“…Intestinal microflora and inflammatory cell infiltrates play critical roles in the pathogenesis of acute colitis. Ceruloplasmin is an acute-phase plasma…”
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Crohn’s Disease Fibroblasts Overproduce the Novel Protein KIAA1199 to Create Proinflammatory Hyaluronan Fragments by Soroosh, Artin, Albeiroti, Sami, West, Gail A, Willard, Belinda, Fiocchi, Claudio, de la Motte, Carol A

“…Background & Aims Crohn’s Disease (CD) is a chronic inflammatory disease of the gastrointestinal tract. Fibrosis, a serious complication of CD, occurs when…”
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Primary Murine Airway Smooth Muscle Cells Exposed to Poly(I,C) or Tunicamycin Synthesize a Leukocyte-adhesive Hyaluronan Matrix by Lauer, Mark E., Mukhopadhyay, Durba, Fulop, Csaba, de la Motte, Carol A., Majors, Alana K., Hascall, Vincent C.

“…Asthmatic attacks often follow viral infections with subsequent airway smooth muscle cell proliferation and the formation of an abnormal hyaluronan…”
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Deficiency of hyaluronan synthase 1 ( Has1 ) results in chronic joint inflammation and widespread intra-articular fibrosis in a murine model of knee joint cartilage damage by Chan, D.D, Xiao, W.F, Li, J, de la Motte, C.A, Sandy, J.D, Plaas, A

“…Summary Objective Articular cartilage defects commonly result from traumatic injury and predispose to degenerative joint diseases. To test the hypothesis that…”
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The Role of Hyaluronan in Innate Defense Responses of the Intestine by de la Motte, Carol A., Kessler, Sean P.

“…Hyaluronan is an abundant extracellular matrix component prevalent in the vertebrate intestinal tract. Here we discuss what is known about hyaluronan…”
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Synovial joint morphogenesis requires the chondrogenic action of Sox5 and Sox6 in growth plate and articular cartilage by Dy, Peter, Smits, Patrick, Silvester, Amber, Penzo-Méndez, Alfredo, Dumitriu, Bogdan, Han, Yu, la Motte, Carol A. de, Kingsley, David M., Lefebvre, Véronique

“…The mechanisms underlying synovial joint development remain poorly understood. Here we use complete and cell-specific gene inactivation to identify the roles…”
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Thrombin receptor-activating peptides differentially stimulate platelet-derived growth factor production, monocytic cell adhesion, and E-selectin expression in human umbilical vein endothelial cells by Shankar, R, de la Motte, C A, Poptic, E J, DiCorleto, P E

“…Recent studies have shown that the synthetic peptides SFL LRN and SFL LRN PND KYEPF (thrombin receptor-activating peptides (TRAP)) derived from the deduced…”
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Intracellular hyaluronan: a new frontier for inflammation? by Hascall, Vincent C, Majors, Alana K, de la Motte, Carol A, Evanko, Stephen P, Wang, Aimin, Drazba, Judith A, Strong, Scott A, Wight, Thomas N

“…A variety of obstacles have hindered the ultrastructural localization of hyaluronan (HA). These include a lack of adequate fixation techniques to prevent the…”
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