Search Results - "de la Fuente, Lorena"

Is it possible to stage schizophrenia? A systematic review by Martínez-Cao, Clara, de la Fuente-Tomás, Lorena, García-Fernández, Ainoa, González-Blanco, Leticia, Sáiz, Pilar A., Garcia-Portilla, María Paz, Bobes, Julio

“…Introduction A staging model is a clinical tool used to define the development of a disease over time. In schizophrenia, authors have proposed different…”
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Are older adults also at higher psychological risk from COVID-19? by García-Portilla, Paz, de la Fuente Tomás, Lorena, Bobes-Bascarán, Teresa, Jiménez Treviño, Luis, Zurrón Madera, Paula, Suárez Álvarez, María, Menéndez Miranda, Isabel, García Álvarez, Leticia, Sáiz Martínez, Pilar A., Bobes, Julio

“…Given the lack of information on the psychological impact of COVID-19 on people aged ≥60, we aimed to describe their psychological responses to this pandemic…”
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Classification of patients with bipolar disorder using k-means clustering by Fuente-Tomas, Lorena de la, Arranz, Belen, Safont, Gemma, Sierra, Pilar, Sanchez-Autet, Monica, Garcia-Blanco, Ana, Garcia-Portilla, Maria P

“…Bipolar disorder (BD) is a heterogeneous disorder needing personalized and shared decisions. We aimed to empirically develop a cluster-based classification…”
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Neutrophil-to-lymphocyte ratio: A potential new peripheral biomarker of suicidal behavior by Velasco, Ángela, Rodríguez-Revuelta, Julia, Olié, Emilie, Abad, Iciar, Fernández-Peláez, Abel, Cazals, Aurélie, Guillaume, Sébastien, de la Fuente-Tomás, Lorena, Jiménez-Treviño, Luis, Gutiérrez, Laura, García-Portilla, Paz, Bobes, Julio, Courtet, Philippe, Sáiz, Pilar A

“…Neutrophil-to-lymphocyte ratio (NLR), monocyte-to-lymphocyte ratio (MLR), and platelet-to-lymphocyte ratio (PLR) have emerged as important peripheral…”
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Will changes in alcohol and tobacco use be seen during the COVID-19 lockdown? by García-Álvarez, Leticia, Fuente-Tomás, Lorena De la, Sáiz, Pilar Alejandra, García-Portilla, Mª Paz, Bobes, Julio

“…Editorial of vol. 32-2…”
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An evaluation of pipelines for DNA variant detection can guide a reanalysis protocol to increase the diagnostic ratio of genetic diseases by Romero, Raquel, de la Fuente, Lorena, Del Pozo-Valero, Marta, Riveiro-Álvarez, Rosa, Trujillo-Tiebas, María José, Martín-Mérida, Inmaculada, Ávila-Fernández, Almudena, Iancu, Ionut-Florin, Perea-Romero, Irene, Núñez-Moreno, Gonzalo, Damián, Alejandra, Rodilla, Cristina, Almoguera, Berta, Cortón, Marta, Ayuso, Carmen, Mínguez, Pablo

“…Clinical exome (CE) sequencing has become a first-tier diagnostic test for hereditary diseases; however, its diagnostic rate is around 30–50%. In this study,…”
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SQANTI: extensive characterization of long-read transcript sequences for quality control in full-length transcriptome identification and quantification by Tardaguila, Manuel, de la Fuente, Lorena, Marti, Cristina, Pereira, Cécile, Pardo-Palacios, Francisco Jose, Del Risco, Hector, Ferrell, Marc, Mellado, Maravillas, Macchietto, Marissa, Verheggen, Kenneth, Edelmann, Mariola, Ezkurdia, Iakes, Vazquez, Jesus, Tress, Michael, Mortazavi, Ali, Martens, Lennart, Rodriguez-Navarro, Susana, Moreno-Manzano, Victoria, Conesa, Ana

“…High-throughput sequencing of full-length transcripts using long reads has paved the way for the discovery of thousands of novel transcripts, even in…”
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A clinical staging model for bipolar disorder: longitudinal approach by de la Fuente-Tomás, Lorena, Sierra, Pilar, Sanchez-Autet, Mónica, Arranz, Belén, García-Blanco, Ana, Safont, Gemma, García-Portilla, Maria P.

“…Bipolar disorder (BD) has been identified as a life-course illness with different clinical manifestations from an at-risk to a late stage, supporting the…”
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The Mediating Role of Impulsivity in the Relationship Between Suicidal Behavior and Early Traumatic Experiences in Depressed Subjects by Dal Santo, Francesco, Carballo, Juan José, Velasco, Angela, Jiménez-Treviño, Luis, Rodríguez-Revuelta, Julia, Martínez-Cao, Clara, Caro-Cañizares, Irene, de la Fuente-Tomás, Lorena, Menéndez-Miranda, Isabel, González-Blanco, Leticia, García-Portilla, Mª Paz, Bobes, Julio, Sáiz, Pilar A.

“…Background: Depressed patients with early traumatic experiences may represent a clinically and biologically distinct subtype, with worse clinical outcomes and…”
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New roles for AP-1/JUNB in cell cycle control and tumorigenic cell invasion via regulation of cyclin E1 and TGF-β2 by Pérez-Benavente, Beatriz, Fathinajafabadi, Alihamze, de la Fuente, Lorena, Gandía, Carolina, Martínez-Férriz, Arantxa, Pardo-Sánchez, José Miguel, Milián, Lara, Conesa, Ana, Romero, Octavio A, Carretero, Julián, Matthiesen, Rune, Jariel-Encontre, Isabelle, Piechaczyk, Marc, Farràs, Rosa

“…JUNB transcription factor contributes to the formation of the ubiquitous transcriptional complex AP-1 involved in the control of many physiological and…”
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tappAS: a comprehensive computational framework for the analysis of the functional impact of differential splicing by de la Fuente, Lorena, Arzalluz-Luque, Ángeles, Tardáguila, Manuel, Del Risco, Héctor, Martí, Cristina, Tarazona, Sonia, Salguero, Pedro, Scott, Raymond, Lerma, Alberto, Alastrue-Agudo, Ana, Bonilla, Pablo, Newman, Jeremy R B, Kosugi, Shunichi, McIntyre, Lauren M, Moreno-Manzano, Victoria, Conesa, Ana

“…Recent advances in long-read sequencing solve inaccuracies in alternative transcript identification of full-length transcripts in short-read RNA-Seq data,…”
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Spanish Validation of the MAP-SR: Two Heads Better Than One for the Assessment of Negative Symptoms of Schizophrenia by Garcia-Portilla, Maria Paz, Garcia-Alvarez, Leticia, Fuente-Tomas, Lorena de la, Santo, Francesco Dal, Velasco, angela, Gonzalez-Blanco, Leticia, Zurron-Madera, Paula, Fonseca-Pedrero, Eduardo, Bobes-Bascaran, Maria Teresa, Saiz, Pilar A, Bobes, Julio

“…Background: There is little research on self-reported negative symptomatology measures in schizophrenia. The aims of this study were to validate the Spanish…”
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Prioritization of New Candidate Genes for Rare Genetic Diseases by a Disease-Aware Evaluation of Heterogeneous Molecular Networks by de la Fuente, Lorena, Del Pozo-Valero, Marta, Perea-Romero, Irene, Blanco-Kelly, Fiona, Fernández-Caballero, Lidia, Cortón, Marta, Ayuso, Carmen, Mínguez, Pablo

“…Screening for pathogenic variants in the diagnosis of rare genetic diseases can now be performed on all genes thanks to the application of whole exome and…”
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Targeted Therapy Modulates the Secretome of Cancer-Associated Fibroblasts to Induce Resistance in HER2-Positive Breast Cancer by Luque, Melani, Sanz-Álvarez, Marta, Santamaría, Andrea, Zazo, Sandra, Cristóbal, Ion, de la Fuente, Lorena, Mínguez, Pablo, Eroles, Pilar, Rovira, Ana, Albanell, Joan, Madoz-Gúrpide, Juan, Rojo, Federico

“…The combination of trastuzumab plus pertuzumab plus docetaxel as a first-line therapy in patients with HER2-positive metastatic breast cancer has provided…”
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Notch-regulated miR-223 targets the aryl hydrocarbon receptor pathway and increases cytokine production in macrophages from rheumatoid arthritis patients by Ogando, Jesús, Tardáguila, Manuel, Díaz-Alderete, Andrea, Usategui, Alicia, Miranda-Ramos, Vanessa, Martínez-Herrera, Dannys Jorge, de la Fuente, Lorena, García-León, María J., Moreno, María C., Escudero, Sara, Cañete, Juan D., Toribio, María L., Cases, Ildefonso, Pascual-Montano, Alberto, Pablos, José Luis, Mañes, Santos

“…Evidence links aryl hydrocarbon receptor (AHR) activation to rheumatoid arthritis (RA) pathogenesis, although results are inconsistent. AHR agonists inhibit…”
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Aggregated Genomic Data as Cohort-Specific Allelic Frequencies can Boost Variants and Genes Prioritization in Non-Solved Cases of Inherited Retinal Dystrophies by Iancu, Ionut-Florin, Perea-Romero, Irene, Núñez-Moreno, Gonzalo, de la Fuente, Lorena, Romero, Raquel, Ávila-Fernandez, Almudena, Trujillo-Tiebas, María José, Riveiro-Álvarez, Rosa, Almoguera, Berta, Martín-Mérida, Inmaculada, Del Pozo-Valero, Marta, Damián-Verde, Alejandra, Cortón, Marta, Ayuso, Carmen, Minguez, Pablo

“…The introduction of NGS in genetic diagnosis has increased the repertoire of variants and genes involved and the amount of genomic information produced. We…”
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Fine Breakpoint Mapping by Genome Sequencing Reveals the First Large X Inversion Disrupting the NHS Gene in a Patient with Syndromic Cataracts by Damián, Alejandra, Ionescu, Raluca Oancea, Rodríguez de Alba, Marta, Tamayo, Alejandra, Trujillo-Tiebas, María José, Cotarelo-Pérez, María Carmen, Pérez Rodríguez, Olga, Villaverde, Cristina, de la Fuente, Lorena, Romero, Raquel, Núñez-Moreno, Gonzalo, Mínguez, Pablo, Ayuso, Carmen, Cortón, Marta

“…Inversions are structural variants that are generally balanced. However, they could lead to gene disruptions or have positional effects leading to diseases…”
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COVID-19 lockdown in people with severe mental disorders in Spain: Do they have a specific psychological reaction compared with other mental disorders and healthy controls? by González-Blanco, Leticia, Dal Santo, Francesco, García-Álvarez, Leticia, de la Fuente-Tomás, Lorena, Moya Lacasa, Carlota, Paniagua, Gonzalo, Sáiz, Pilar A., García-Portilla, María Paz, Bobes, Julio

“…The COVID-19 pandemic and the lockdown restrictions could have adverse consequences for patients with severe mental disorders (SMD). Here, we aim to compare…”
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Factors associated with alcohol and tobacco consumption as a coping strategy to deal with the coronavirus disease (COVID-19) pandemic and lockdown in Spain by Martínez-Cao, Clara, de la Fuente-Tomás, Lorena, Menéndez-Miranda, Isabel, Velasco, Ángela, Zurrón-Madera, Paula, García-Álvarez, Leticia, Sáiz, Pilar A., Garcia-Portilla, María Paz, Bobes, Julio

“…•Previous data suggest an increase in alcohol and tobacco consumption during the COVID-19 pandemic and lockdown.•Little is known about the specific factors…”
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Diurnal cortisol throughout pregnancy and its association with maternal depressive symptoms and birth outcomes by Castro-Quintas, Águeda, Eixarch, Elisenda, Martin-Gonzalez, Nerea San, Daura-Corral, Maria, Marques-Feixa, Laia, Palma-Gudiel, Helena, Rocavert-Barranco, Mireia, Miguel-Valero, Alba, Monteserín-García, Jose Luis, de la Fuente-Tomás, Lorena, Crispi, Fátima, Arias, Barbara, García-Portilla, María Paz, Fañanás, Lourdes

“…Depression during pregnancy is a common complication that can negatively affect fetal health and birth outcomes. Cortisol is believed to be a key mediator of…”
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