Search Results - "de la Cruz, J P"
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Dietary Virgin Olive Oil Reduces Oxidative Stress and Cellular Damage in Rat Brain Slices Subjected to Hypoxia-Reoxygenation
Published in Lipids (01-10-2007)“…We investigated how virgin olive oil (VOO) affected platelet and hypoxic brain damage in rats. Rats were given VOO orally for 30 days at 0.25 or 0.5 mL kg-¹…”
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Beyond lectures and practical courses: Teaching pharmacology using imaginative pedagogical tools
Published in Pharmacological research (01-04-2024)“…Pharmacology has broadened its scope considerably in recent decades. Initially, it was of interest to chemists, doctors and pharmacists. In recent years,…”
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Population genetics of the endangered Cantabrian capercaillie in northern Spain
Published in Animal conservation (01-06-2011)“…In this study, we examine the effects of habitat fragmentation on the genetic structure of the Cantabrian capercaillie Tetrao urogallus cantabricus, based on…”
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Differences in the In Vitro Antiplatelet Effect of Dexibuprofen, Ibuprofen, and Flurbiprofen in Human Blood
Published in Anesthesia and analgesia (01-12-2010)“…In this study, we compared the in vitro pharmacodynamic profile of dexibuprofen, ibuprofen, and flurbiprofen to identify possible differences in antiplatelet…”
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Effects of propofol on the leukocyte nitric oxide pathway: in vitro and ex vivo studies in surgical patients
Published in Naunyn-Schmiedeberg's archives of pharmacology (01-01-2008)“…This study was designed to evaluate the mechanism by which propofol modifies leukocyte production of nitric oxide (NO) in humans. In vitro experiments used…”
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Effects of the selective inhibition of platelet thromboxane synthesis on the platelet‐subendothelium interaction
Published in British journal of pharmacology (01-12-2002)“…Drugs that inhibit TxA2 synthesis are used to reduce platelet aggregation. The aim of this study was to compare the effects of a cyclo‐oxygenase (COX)…”
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7
Effect of aspirin plus dipyridamole on the retinal vascular pattern in experimental diabetes mellitus
Published in The Journal of pharmacology and experimental therapeutics (01-01-1997)“…Platelet hyperactivity has been one of the mechanisms implicated in the pathogenesis of diabetic retinopathy. Antiplatelet agents have been shown, in…”
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Role of the catechol group in the antioxidant and neuroprotective effects of virgin olive oil components in rat brain
Published in The Journal of nutritional biochemistry (01-05-2015)“…The aim of the present study was to determine the role of the catechol group in the antioxidant and neuroprotective effects of minor components of virgin olive…”
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Inhibition of ferrous‐induced lipid peroxidation by pyrimido‐pyrimidine derivatives in human liver membranes
Published in Lipids (01-03-1992)“…The effects of pyrimido‐pyrimidine derivatives (dipyridamole, RA‐642, and RA‐233) on lipid peroxidation, using d‐α‐tocopherol as standard, were studied in…”
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10
Antioxidant effect of acetylsalicylic and salicylic acid in rat brain slices subjected to hypoxia
Published in Journal of neuroscience research (15-01-2004)“…Acetylsalicylic acid (ASA) reduces the incidence of ischemic stroke mainly through its antithrombotic action; however, it also has a direct neuroprotective…”
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Antioxidant effects of a single dose of acetylsalicylic acid and salicylic acid in rat brain slices subjected to oxygen-glucose deprivation in relation with its antiplatelet effect
Published in Neuroscience letters (01-04-2004)“…The aim of the present study was to analyze the relative participation of the antiplatelet and the antioxidant effects of acetylsalicylic acid (ASA) and…”
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Effect of dietary supplementation with evening primrose oil on vascular thrombogenesis in hyperlipemic rabbits
Published in Thrombosis and haemostasis (01-10-1998)“…The dietary intake of saturated fatty acids affects arteriosclerosis. We studied the effect of supplementation (15% wt/wt) of a hyperlipemic diet (1.3%…”
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The effect of propofol on oxidative stress in platelets from surgical patients
Published in Anesthesia and analgesia (01-10-1999)“…We investigated the changes in oxidative stress in platelets from surgical patients anesthetized with propofol. We studied 60 surgical patients (ASA physical…”
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Antiplatelet effect of new lipophilic hydroxytyrosol alkyl ether derivatives in human blood
Published in European journal of nutrition (01-03-2013)“…Purpose To investigate the in vitro antiplatelet and anti-inflammatory effects of five alkyl hydroxytyrosol (HT) ether derivatives in human whole blood and…”
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The in vitro effects of propofol on tissular oxidative stress in the rat
Published in Anesthesia and analgesia (01-11-1998)“…This study was designed to evaluate the in vitro effects of propofol on lipid peroxide formation and the glutathione antioxidant system in some tissues of…”
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Neuroprotective effect of alkyl hydroxytyrosyl ethers in rat brain slices subjected to a hypoxia-reoxygenation model
Published in Food chemistry (15-10-2012)“…► Hydroxytyrosyl alkyl ether derivatives exerted a neuroprotective effect in rat brain slices. ► The inhibition of lipid peroxidation was directly related to…”
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Effects of triflusal on oxidative stress, prostaglandin production and nitric oxide pathway in a model of anoxia-reoxygenation in rat brain slices
Published in Brain research (18-06-2004)“…Acetylsalicylic acid (ASA) is the most widely used drug in the prevention of ischemic vascular accidents, mainly because of its antithrombotic effect…”
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Influence of vitamin E on the antiplatelet effect of acetylsalicylic acid in human blood
Published in Platelets (Edinburgh) (01-05-2005)“…We analysed the in vitro interaction between acetylsalicylic acid and vitamin E on the principal antiplatelet sites of action of acetylsalicylic acid, i.e.,…”
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Effect of S-adenosyl- l-methionine on rat brain oxidative stress damage in a combined model of permanent focal ischemia and global ischemia-reperfusion
Published in Brain research (10-11-2000)“…We analyzed the effects of S-adenosyl- l-methionine (SAM) on tissue oxidative status in a combined model of permanent focal ischemia and global reperfusion in…”
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Propofol Inhibits In Vitro Platelet Aggregation in Human Whole Blood
Published in Anesthesia and analgesia (01-04-1997)“…To help clarify the mechanism of propofol-induced vasodilation, we investigated whether propofol, at concentrations ranging from 10 to 10 M, inhibited platelet…”
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