Search Results - "de Wilde, Peter C.M"

No Detectable Hypoxia in Malignant Salivary Gland Tumors: Preliminary Results by Wijffels, Karien I.E.M., M.D, Hoogsteen, Ilse J., M.D, Lok, Jasper, B.Sc, Rijken, Paulus F.J.W., M.Sc, Marres, Henri A.M., M.D., Ph.D, de Wilde, Peter C.M., M.D., Ph.D, van der Kogel, Albert J., Ph.D, Kaanders, Johannes H.A.M., M.D., Ph.D

“…Purpose Hypoxia is detected in most solid tumors and is associated with malignant progression and adverse treatment outcomes. However, the oxygenation status…”
Get full text

Rational approach to diagnosis and treatment of ameloblastomas and odontogenic keratocysts by Chapelle, Karen A.O.M., Stoelinga, Paul J.W., de Wilde, Peter C.M., Brouns, John J.A., Voorsmit, Ralph A.C.A.

“…We present decision trees on the treatment of cystic lesions of the jaws based on their location. We give special consideration to the treatment of potentially…”
Get full text

Expression of p14ARF, p16INK4a and p53 in relation to HPV in (pre‐)malignant squamous skin tumours by Küsters‐Vandevelde, Heidi V.N., de Koning, Maurits N.C., Melchers, Willem J.G., Quint, Wim G.V., de Wilde, Peter C.M., de Jong, Elke M.G.J., van de Kerkhof, Peter C.M., Blokx, Willeke A.M.

“…Studies in cervical dysplasia have reported overexpression of the tumour suppressors p14 and p16 – and absence of p53 – in high‐risk human papilloma virus…”
Get full text

Expression of p14 ARF , p16 INK4a and p53 in relation to HPV in (pre‐)malignant squamous skin tumours by Küsters‐Vandevelde, Heidi V.N., de Koning, Maurits N.C., Melchers, Willem J.G., Quint, Wim G.V., de Wilde, Peter C.M., de Jong, Elke M.G.J., van de Kerkhof, Peter C.M., Blokx, Willeke A.M.

“…Studies in cervical dysplasia have reported overexpression of the tumour suppressors p14 and p16 – and absence of p53 – in high‐risk human papilloma virus…”
Get full text

Recurrent melanotic neuroectodermal tumor of infancy: a proposal for treatment protocol with surgery and adjuvant chemotherapy by Neven, Johannus, MD, DMD, Kaa, Christine Hulsbergen–van der, MD, Groot-Loonen, Jacqueline, MD, PhD, de Wilde, Peter C.M., DMD, PhD, Merkx, Matthais A.W., MD, DMD, PhD

“…The case of a 4-month-old male infant treated with combined surgery and chemotherapy for an aggressive recurrent melanotic neuroectodermal tumor of infancy…”
Get full text

P16 and p53 Expression in (Pre)Malignant Epidermal Tumors of Renal Transplant Recipients and Immunocompetent Individuals by Blokx, Willeke A M, de Jong, Elke M G J, de Wilde, Peter C M, Bulten, Johan, Link, Monique M G M, Ruiter, Dirk J, van de Kerkhof, Peter C M

“…Ultraviolet (UV) radiation is a prevailing factor implicated in the etiology of keratinocytic intraepidermal neoplasia (KIN) and squamous cell carcinomas…”
Get full text

Different chromosomal imbalances in metastasized and nonmetastasized tongue carcinomas identified by comparative genomic hybridization by Hannen, Egied J.M, Macville, Merryn V.E, Wienk, Sandra M, Slootweg, Pieter J, Manni, Johannes J, Hanselaar, Antonius G.J.M, de Wilde, Peter C.M

“…Tumors of different metastatic behavior possibly differ in genomic constitution. We identified molecular cytogenetic differences between a group of…”
Get full text

Multiple complications due to osteoradionecrosis in a patient with thromboangiitis obliterans by Barkhuysen, Richard, MD, DMD, Janssens, Geert O.R.J., MD, de Wilde, Peter C.M., DMD, PhD, Merkx, Matthias A.W., MD, DMD, PhD

“…A case is presented of a patient with thromboangiitis obliterans (TAO) who developed severe necrosis of the intraoral soft tissues and maxillary and mandibular…”
Get full text

A panel of p16(INK4A), MIB1 and p53 proteins can distinguish between the 2 pathways leading to vulvar squamous cell carcinoma by Hoevenaars, Brigiet M, van der Avoort, Irene A M, de Wilde, Peter C M, Massuger, Leon F A G, Melchers, Willem J G, de Hullu, Joanne A, Bulten, Johan

“…Two pathways leading to vulvar squamous cell carcinoma (SCC) exist. The expression of proliferation- and cell-cycle-related biomarkers and the presence of…”
Get full text

Pimonidazole binding and tumor vascularity predict for treatment outcome in head and neck cancer by KAANDERS, Johannes H. A. M, WIJFFELS, Karien I. E. M, MARRES, Henri A. M, LJUNGKVIST, Anna S. E, POP, Lucas A. M, VAN DEN HOOGEN, Franciscus J. A, DE WILDE, Peter C. M, BUSSINK, Johan, RALEIGH, James A, VAN DER KOGEL, Albert J

“…Hypoxia is associated with tumor aggressiveness and is an important cause of resistance to radiation treatment. Assays of tumor hypoxia could provide selection…”
Get full text

Interleukin-12 has no Effect on Vascular Density, Perfusion, Hypoxia and Proliferation of an Implanted Human Squamous Cell Carcinoma Xenograft Tumour Despite Up-regulation of ICAM-1 by VAN HERPEN, Carla M. L, BUSSINK, Johan, VAN DER KOGEL, Albert J, PEETERS, Wenny J. M, VAN DER VOORT, Robbert, VAN SCHIJNDEL, Anita, DE WILDE, Peter C. M, ADEMA, Gosse J, DE MULDER, Pieter H. M

“…Background: Interleukin-12 is an anti-angiogenic and antitumor agent in many transplanted murine tumour models. In a previous clinical study in head and neck…”
Get full text

The prognostic value of endogenous hypoxia-related markers for head and neck squamous cell carcinomas treated with ARCON by Jonathan, Ruth A., Wijffels, Karien I.E.M., Peeters, Wenny, de Wilde, Peter C.M., Marres, Henri A.M., Merkx, Matthias A.W., Oosterwijk, Egbert, van der Kogel, Albert J., Kaanders, Johannes H.A.M.

“…Hypoxic radioresistance is an important cause for treatment failure in a number of tumor types including head and neck cancers. Recent studies suggest that…”
Get full text

Etanercept in the treatment of patients with primary Sjögren's syndrome: A pilot study by ZANDBELT, Michiel M, DE WILDE, Peter C. M, VAN DAMME, Philip A, HOYNG, Carel B, VAN DE PUTTE, Leo B. A, VAN DEN HOOGEN, Frank H. J

“…This pilot study evaluated the effect of anti-tumor necrosis factor-a antiinflammatory treatment with etanercept (Enbrel(R)) on sicca, systemic, and…”
Get full text

A panel of p16 INK4A , MIB1 and p53 proteins can distinguish between the 2 pathways leading to vulvar squamous cell carcinoma by Hoevenaars, Brigiet M., van der Avoort, Irene A.M., de Wilde, Peter C.M., Massuger, Leon F.A.G., Melchers, Willem J.G., de Hullu, Joanne A., Bulten, Johan

“…Two pathways leading to vulvar squamous cell carcinoma (SCC) exist. The expression of proliferation‐ and cell‐cycle‐related biomarkers and the presence of…”
Get full text

MIB1 expression in basal cell layer: a diagnostic tool to identify premalignancies of the vulva by van der Avoort, Irene A M, van der Laak, Jeroen A W M, Paffen, Ard, Grefte, Johanna M M, Massuger, Leon F A G, de Wilde, Peter C M, de Hullu, Joanne A, Bulten, Johan

“…Lichen sclerosus, high-grade usual vulvar intraepithelial neoplasia (VIN) and differentiated VIN have a different malignant potential. The objective of this…”
Get full text

Short Fragment Polymerase Chain Reaction Reverse Hybridization Line Probe Assay to Detect and Genotype a Broad Spectrum of Human Papillomavirus Types : Clinical Evaluation and Follow-Up by Melchers, Willem J. G, Bakkers, Judith M. J .E, Wang, Jinhua, de Wilde, Peter C. M, Boonstra, Henk, Quint, Wim G. V, Hanselaar, Antonius G. J. M

“…The purpose of this study was to detect and genotype 16 different human papilloma virus (HPV) types simultaneously using a short fragment polymerase chain…”
Get full text

A panel of p16INK4A, MIB1 and p53 proteins can distinguish between the 2 pathways leading to vulvar squamous cell carcinoma by Hoevenaars, Brigiet M., van der Avoort, Irene A.M., de Wilde, Peter C.M., Massuger, Leon F.A.G., Melchers, Willem J.G., de Hullu, Joanne A., Bulten, Johan

“…Two pathways leading to vulvar squamous cell carcinoma (SCC) exist. The expression of proliferation‐ and cell‐cycle‐related biomarkers and the presence of…”
Get full text

Treatment results of patients with a squamous cell carcinoma of the buccal mucosa by Coppen, Casper, de Wilde, Peter C.M., Pop, Lucas A., van den Hoogen, Franciscus J.A., Merkx, Matthias A.W.

“…The purpose of this study was to evaluate outcome and value of follow-up of squamous cell carcinoma (SCC) of the buccal mucosa in patients treated at the…”
Get full text

p14 ARF and p16 INK4A, two products of the same gene, are differently expressed in cervical intraepithelial neoplasia by Bulten, Johan, van der Avoort, Irene A.M., Melchers, Willem J.G., Massuger, Leon F.A.G., Grefte, Johanna M.M., Hanselaar, Antonius G.J.M., de Wilde, Peter C.M.

“…To study the expression patterns of two different tumor suppressor proteins p16 INK4A and p14 ARF in cervical lesions. Both proteins are encoded by the same…”
Get full text

p14ARF and p16INK4A, two products of the same gene, are differently expressed in cervical intraepithelial neoplasia by Bulten, Johan, van der Avoort, Irene A M, Melchers, Willem J G, Massuger, Leon F A G, Grefte, Johanna M M, Hanselaar, Antonius G J M, de Wilde, Peter C M

“…To study the expression patterns of two different tumor suppressor proteins p16INK4A and p14ARF in cervical lesions. Both proteins are encoded by the same…”
Get full text