Search Results - "de Wilde, Peter C. M"
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MIB1 expression in basal cell layer: a diagnostic tool to identify premalignancies of the vulva
Published in Modern pathology (01-07-2007)“…Lichen sclerosus, high-grade usual vulvar intraepithelial neoplasia (VIN) and differentiated VIN have a different malignant potential. The objective of this…”
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Short Fragment Polymerase Chain Reaction Reverse Hybridization Line Probe Assay to Detect and Genotype a Broad Spectrum of Human Papillomavirus Types : Clinical Evaluation and Follow-Up
Published in The American journal of pathology (01-11-1999)“…The purpose of this study was to detect and genotype 16 different human papilloma virus (HPV) types simultaneously using a short fragment polymerase chain…”
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A panel of p16(INK4A), MIB1 and p53 proteins can distinguish between the 2 pathways leading to vulvar squamous cell carcinoma
Published in International journal of cancer (15-12-2008)“…Two pathways leading to vulvar squamous cell carcinoma (SCC) exist. The expression of proliferation- and cell-cycle-related biomarkers and the presence of…”
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Pimonidazole binding and tumor vascularity predict for treatment outcome in head and neck cancer
Published in Cancer research (Chicago, Ill.) (01-12-2002)“…Hypoxia is associated with tumor aggressiveness and is an important cause of resistance to radiation treatment. Assays of tumor hypoxia could provide selection…”
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Treatment results of patients with a squamous cell carcinoma of the buccal mucosa
Published in Oral oncology (01-09-2006)“…The purpose of this study was to evaluate outcome and value of follow-up of squamous cell carcinoma (SCC) of the buccal mucosa in patients treated at the…”
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Recurrent melanotic neuroectodermal tumor of infancy: a proposal for treatment protocol with surgery and adjuvant chemotherapy
Published in Oral surgery, oral medicine, oral pathology, oral radiology and endodontics (01-10-2008)“…The case of a 4-month-old male infant treated with combined surgery and chemotherapy for an aggressive recurrent melanotic neuroectodermal tumor of infancy…”
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The prognostic value of endogenous hypoxia-related markers for head and neck squamous cell carcinomas treated with ARCON
Published in Radiotherapy and oncology (01-06-2006)“…Hypoxic radioresistance is an important cause for treatment failure in a number of tumor types including head and neck cancers. Recent studies suggest that…”
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Objective assessment of cancer biomarkers using semi-rare event detection
Published in Analytical cellular pathology (Amsterdam) (2007)“…Objective and reproducible assessment of cancer biomarkers may be performed using rare event detection systems. Because many biomarkers are not true 'rare…”
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Computer assisted analysis of the microvasculature in metastasized and nonmetastasized squamous cell carcinomas of the tongue
Published in Head & neck (01-07-2002)“…Background Quantification of microvessels in solid malignancies is regarded as a potential test to predict their clinicobiologic behavior. However, discordant…”
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Quantitation of Ki-67 Expression in the Differential Diagnosis of Reserve Cell Hyperplasia vs. Small Cell Lung Carcinoma
Published in Acta cytologica (01-09-2004)“…To investigate whether the detection of proliferation-associated Ki-67 antigen may be of value in differentiating between reserve cell hyperplasia (RCH) and…”
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Expression of p14ARF, p16INK4a and p53 in relation to HPV in (pre‐)malignant squamous skin tumours
Published in Journal of cellular and molecular medicine (01-08-2009)“…Studies in cervical dysplasia have reported overexpression of the tumour suppressors p14 and p16 – and absence of p53 – in high‐risk human papilloma virus…”
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No Detectable Hypoxia in Malignant Salivary Gland Tumors: Preliminary Results
Published in International journal of radiation oncology, biology, physics (01-04-2009)“…Purpose Hypoxia is detected in most solid tumors and is associated with malignant progression and adverse treatment outcomes. However, the oxygenation status…”
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Rational approach to diagnosis and treatment of ameloblastomas and odontogenic keratocysts
Published in British journal of oral & maxillofacial surgery (01-10-2004)“…We present decision trees on the treatment of cystic lesions of the jaws based on their location. We give special consideration to the treatment of potentially…”
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Markers for Nodal Metastasis in Head and Neck Squamous Cell Cancer
Published in Archives of otolaryngology, head & neck surgery (01-05-2002)“…OBJECTIVE To identify markers that are relevant as predictors of lymph node metastasis in head and neck squamous cell cancer. DESIGN Expression of p53, Rb,…”
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INK4-ARF and p53 mutations in metastatic cutaneous squamous cell carcinoma: Case report and archival study on the use of INK4a-ARF and p53 mutation analysis in identification of the corresponding primary tumor
Published in The American journal of surgical pathology (2005)“…So far, histopathologic, immunohistochemical and molecular properties of metastatic cutaneous squamous cell carcinomas (CSCCs) are relatively unexplored. In…”
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Numerical aberrations of chromosome 1 in cervical intraepithelial neoplasia are strongly associated with infection with high-risk human papillomavirus types
Published in The Journal of pathology (01-11-2002)“…The aims of this study were to assess the relationships between numerical aberrations of chromosome 1 and the presence of high‐risk human papillomavirus (HPV)…”
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Multiple complications due to osteoradionecrosis in a patient with thromboangiitis obliterans
Published in Oral surgery, oral medicine, oral pathology, oral radiology and endodontics (01-07-2007)“…A case is presented of a patient with thromboangiitis obliterans (TAO) who developed severe necrosis of the intraoral soft tissues and maxillary and mandibular…”
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Different chromosomal imbalances in metastasized and nonmetastasized tongue carcinomas identified by comparative genomic hybridization
Published in Oral oncology (01-04-2004)“…Tumors of different metastatic behavior possibly differ in genomic constitution. We identified molecular cytogenetic differences between a group of…”
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Interleukin-12 has no Effect on Vascular Density, Perfusion, Hypoxia and Proliferation of an Implanted Human Squamous Cell Carcinoma Xenograft Tumour Despite Up-regulation of ICAM-1
Published in Anticancer research (01-03-2005)“…Background: Interleukin-12 is an anti-angiogenic and antitumor agent in many transplanted murine tumour models. In a previous clinical study in head and neck…”
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