Search Results - "de Wiele, Tom"
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Experimental models to study intestinal microbes-mucus interactions in health and disease
Published in FEMS microbiology reviews (01-09-2019)“…A close symbiotic relationship exists between the intestinal microbiota and its host. A critical component of gut homeostasis is the presence of a mucus layer…”
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Gut Microbiota Dysbiosis in Postweaning Piglets: Understanding the Keys to Health
Published in Trends in microbiology (Regular ed.) (01-10-2017)“…Weaning is a critical event in the pig’s life cycle, frequently associated with severe enteric infections and overuse of antibiotics; this raises serious…”
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The small intestine: dining table of host–microbiota meetings
Published in FEMS microbiology reviews (01-05-2023)“…Abstract Growing evidence suggests the importance of the small intestinal bacteria in the diet–host–microbiota dialogue in various facets of health and…”
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Nutrient load acts as a driver of gut microbiota load, community composition and metabolic functionality in the simulator of the human intestinal microbial ecosystem
Published in FEMS microbiology ecology (01-09-2021)“…ABSTRACT A recently introduced quantitative framework for gut microbiota analysis indicated that microbial load alterations can be linked to various diseases,…”
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Characterisation of the human uterine microbiome in non-pregnant women through deep sequencing of the V1-2 region of the 16S rRNA gene
Published in PeerJ (San Francisco, CA) (19-01-2016)“…Background. It is widely assumed that the uterine cavity in non-pregnant women is physiologically sterile, also as a premise to the long-held view that human…”
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Dose-Dependent Effects of Dietary Xylooligosaccharides Supplementation on Microbiota, Fermentation and Metabolism in Healthy Adult Cats
Published in Molecules (Basel, Switzerland) (29-10-2020)“…In order to investigate the effect and appropriate dose of prebiotics, this study evaluated the effect of two levels of xylooligosaccharides (XOS) in cats…”
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The intestinal environment in health and disease - recent insights on the potential of intestinal bacteria to influence human health
Published in Current pharmaceutical design (01-06-2009)“…The human intestine is colonized by a complex microbial ecosystem, which could be considered as a separate organ within the human host, having a coding…”
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Metabolic fate of polyphenols in the human superorganism
Published in Proceedings of the National Academy of Sciences - PNAS (15-03-2011)“…Dietary polyphenols are components of many foods such as tea, fruit and vegetables and are associated with several beneficial health effects although, so far,…”
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Effects of Olive and Pomegranate By-Products on Human Microbiota: A Study Using the SHIME ® in Vitro Simulator
Published in Molecules (Basel, Switzerland) (21-10-2019)“…Two by-products containing phenols and polysaccharides, a "pâté" (OP) from the extra virgin olive oil milling process and a decoction of pomegranate mesocarp…”
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Oral biofilms exposure to chlorhexidine results in altered microbial composition and metabolic profile
Published in NPJ biofilms and microbiomes (20-03-2020)“…Oral diseases (e.g., dental caries, periodontitis) are developed when the healthy oral microbiome is imbalanced allowing the increase of pathobiont strains…”
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Commensal microbiota influence systemic autoimmune responses
Published in The EMBO journal (12-02-2015)“…Antinuclear antibodies are a hallmark feature of generalized autoimmune diseases, including systemic lupus erythematosus and systemic sclerosis. However, the…”
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Exploring the methanogen and bacterial communities of rumen environments: solid adherent, fluid and epimural
Published in FEMS microbiology ecology (01-03-2017)“…Abstract The rumen microbiome occupies a central role in animal health and productivity. A better understanding of the rumen ecosystem is essential to increase…”
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Gastrointestinal Microbes Increase Arsenic Bioaccessibility of Ingested Mine Tailings Using the Simulator of the Human Intestinal Microbial Ecosystem
Published in Environmental science & technology (01-08-2007)“…It is widely accepted that the use of total metal concentrations in soil overestimates metal risk from human ingestion of contaminated soils. In vitro…”
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In Vitro Bioconversion of Polyphenols from Black Tea and Red Wine/Grape Juice by Human Intestinal Microbiota Displays Strong Interindividual Variability
Published in Journal of agricultural and food chemistry (22-09-2010)“…Dietary polyphenols in tea and wine have been associated with beneficial health effects. After ingestion, most polyphenols are metabolized by the colonic…”
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Dual and Triple Epithelial Coculture Model Systems with Donor-Derived Microbiota and THP-1 Macrophages To Mimic Host-Microbe Interactions in the Human Sinonasal Cavities
Published in mSphere (15-01-2020)“…The epithelium of the human sinonasal cavities is colonized by a diverse microbial community, modulating epithelial development and immune priming and playing…”
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Metabolic fate of ochratoxin A as a coffee contaminant in a dynamic simulator of the human colon
Published in Food chemistry (15-12-2013)“…•Ochratoxin A degradation by the human gut microbiota in a dynamic in vitro system.•Biodegradation in the descending colon, with two metabolites…”
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HPLC-ICP-MS method development to monitor arsenic speciation changes by human gut microbiota
Published in Biomedical chromatography (01-04-2012)“…ABSTRACT Inorganic arsenic (iAs) has been classified as a type 1 carcinogen and has also been linked to several noncancerous health effects. Prior to 1995, the…”
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Exploration of isoxanthohumol bioconversion from spent hops into 8-prenylnaringenin using resting cells of Eubacterium limosum
Published in AMB Express (24-04-2020)“…Hops is an almost unique source of the potent phytoestrogen 8-prenylnaringenin (8-PN). As hops contain only low levels of 8-PN, synthesis may be more…”
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Candida species-specific colonization in the healthy and impaired human gastrointestinal tract as simulated using the Mucosal Ileum-SHIME® model
Published in FEMS microbiology ecology (13-08-2024)“…Candida species primarily exist as harmless commensals in the gastrointestinal tract of warm-blooded animals. However, they can also cause life-threatening…”
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Microbial odor profile of polyester and cotton clothes after a fitness session
Published in Applied and Environmental Microbiology (01-11-2014)“…Clothing textiles protect our human body against external factors. These textiles are not sterile and can harbor high bacterial counts as sweat and bacteria…”
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