Search Results - "de Wendt, Christian"

Contraction-Mediated Glucose Transport in Skeletal Muscle Is Regulated by a Framework of AMPK, TBC1D1/4, and Rac1 by de Wendt, Christian, Espelage, Lena, Eickelschulte, Samaneh, Springer, Christian, Toska, Laura, Scheel, Anna, Bedou, Awovi Didi, Benninghoff, Tim, Cames, Sandra, Stermann, Torben, Chadt, Alexandra, Al-Hasani, Hadi

“…The two closely related RabGTPase-activating proteins (RabGAPs) TBC1D1 and TBC1D4, both substrates for AMPK, play important roles in exercise metabolism and…”
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TBC1D4 Is Necessary for Enhancing Muscle Insulin Sensitivity in Response to AICAR and Contraction by Kjøbsted, Rasmus, Chadt, Alexandra, Jørgensen, Nicolas O, Kido, Kohei, Larsen, Jeppe K, de Wendt, Christian, Al-Hasani, Hadi, Wojtaszewski, Jørgen F P

“…Muscle insulin sensitivity for stimulating glucose uptake is enhanced in the period after a single bout of exercise. We recently demonstrated that AMPK is…”
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Deletion of Both Rab-GTPase-Activating Proteins TBC14KO and TBC1D4 in Mice Eliminates Insulin- and AICAR-Stimulated Glucose Transport by Chadt, Alexandra, Immisch, Anja, Wendt, Christian de, Springer, Christian, Zhou, Zhou, Stermann, Torben, Holman, Geoffrey D, Loffing-Cueni, Dominique, Loffing, Johannes, Joost, Hans-Georg, Al-Hasani, Hadi

“…The Rab-GTPase-activating proteins TBC14KO and TBC1D4 (AS160) were previously shown to regulate GLUT4 translocation in response to activation of AKT and…”
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Deletion of both Rab-GTPase–activating proteins TBC1D1 and TBC1D4 in mice eliminates insulin- and AICAR-stimulated glucose transport [corrected] by Chadt, Alexandra, Immisch, Anja, de Wendt, Christian, Springer, Christian, Zhou, Zhou, Stermann, Torben, Holman, Geoffrey D, Loffing-Cueni, Dominique, Loffing, Johannes, Joost, Hans-Georg, Al-Hasani, Hadi

“…The Rab-GTPase–activating proteins TBC1D1 and TBC1D4 (AS160) were previously shown to regulate GLUT4 translocation in response to activation of AKT and…”
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Histone deacetylase 5 regulates interleukin 6 secretion and insulin action in skeletal muscle by Klymenko, Oleksiy, Brecklinghaus, Tim, Dille, Matthias, Springer, Christian, de Wendt, Christian, Altenhofen, Delsi, Binsch, Christian, Knebel, Birgit, Scheller, Jürgen, Hardt, Christopher, Herwig, Ralf, Chadt, Alexandra, Pfluger, Paul T., Al-Hasani, Hadi, Kabra, Dhiraj G.

“…Physical exercise training is associated with increased glucose uptake in skeletal muscle and improved glycemic control. HDAC5, a class IIa histone…”
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AKT and AMP-activated protein kinase regulate TBC1D1 through phosphorylation and its interaction with the cytosolic tail of insulin-regulated aminopeptidase IRAP by Mafakheri, Samaneh, Flörke, Ralf R., Kanngießer, Sibylle, Hartwig, Sonja, Espelage, Lena, De Wendt, Christian, Schönberger, Tina, Hamker, Nele, Lehr, Stefan, Chadt, Alexandra, Al-Hasani, Hadi

“…In skeletal muscle, the Rab GTPase-activating (GAP) protein TBC1D1 is phosphorylated by AKT and AMP-activated protein kinase (AMPK) in response to insulin and…”
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Deletion of the RabGAP TBC1D1 Leads to Enhanced Insulin Secretion and Fatty Acid Oxidation in Islets From Male Mice by Stermann, Torben, Menzel, Franziska, Weidlich, Carmen, Jeruschke, Kay, Weiss, Jürgen, Altenhofen, Delsi, Benninghoff, Tim, Pujol, Anna, Bosch, Fatima, Rustenbeck, Ingo, Ouwens, D Margriet, Thoresen, G Hege, de Wendt, Christian, Lebek, Sandra, Schallschmidt, Tanja, Kragl, Martin, Lammert, Eckhard, Chadt, Alexandra, Al-Hasani, Hadi

“…The Rab guanosine triphosphatase-activating protein (RabGAP) TBC1D1 has been shown to be a key regulator of glucose and lipid metabolism in skeletal muscle…”
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Deletion of both Rab-GTPase-activating proteins TBC14KO and TBC1D4 in mice eliminates insulin- and AICAR-stimulated glucose transport. Diabetes 2015;64:746-759 by Chadt, Alexandra, Immisch, Anja, de Wendt, Christian, Springer, Christian, Zhou, Zhou, Stermann, Torben, Holman, Geoffrey D, Loffing-Cueni, Dominique, Loffing, Johannes, Joost, Hans-Georg, Al-Hasani, Hadi

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