Search Results - "de Vries, Victor C"
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Mast Cells Condition Dendritic Cells to Mediate Allograft Tolerance
Published in Immunity (Cambridge, Mass.) (28-10-2011)“…Peripheral tolerance orchestrated by regulatory T cells, dendritic cells (DCs), and mast cells (MCs) has been studied in several models including skin…”
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Journal Article -
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Molecular mechanism and function of CD40/CD40L engagement in the immune system
Published in Immunological reviews (01-05-2009)“…During the generation of a successful adaptive immune response, multiple molecular signals are required. A primary signal is the binding of cognate antigen to…”
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Programmed death 1 ligand signaling regulates the generation of adaptive Foxp3⁺CD4⁺ regulatory T cells
Published in Proceedings of the National Academy of Sciences - PNAS (08-07-2008)“…Although mature dendritic cells (DCs) are potent initiators of adaptive immune response, immature steady-state DCs contribute to immune tolerance. In this…”
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Journal Article -
4
Tryptophan hydroxylase-1 regulates immune tolerance and inflammation
Published in The Journal of experimental medicine (22-10-2012)“…Nutrient deprivation based on the loss of essential amino acids by catabolic enzymes in the microenvironment is a critical means to control inflammatory…”
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5
immortality of humoral immunity
Published in Immunological reviews (01-07-2010)“…Decades of high-titered antibody are sustained due to the persistence of memory B cells and long-lived plasma cells (PCs). The differentiation of each of these…”
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Journal Article -
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Mast Cells Condition Dendritic Cells to Mediate Allograft Tolerance
Published in Immunity (Cambridge, Mass.) (23-12-2011)Get full text
Journal Article -
7
The distinctive germinal center phase of IgE+ B lymphocytes limits their contribution to the classical memory response
Published in The Journal of experimental medicine (18-11-2013)“…The mechanisms involved in the maintenance of memory IgE responses are poorly understood, and the role played by germinal center (GC) IgE(+) cells in memory…”
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Journal Article -
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Mast cell mediators in tolerance
Published in Current opinion in immunology (01-10-2010)“…Our knowledge on the function of mast cells (MC) as part of the immune system has expanded from ‘key cells in mediating allergy’ to ‘tunable regulators of the…”
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Induction of postsurgical tumor immunity and T-cell memory by a poorly immunogenic tumor
Published in Cancer research (Chicago, Ill.) (01-07-2007)“…The generation of protective CD8 T-cell memory against tumor-expressed self-antigens is an important but elusive goal of cancer immunotherapy. The possibility…”
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The enigmatic role of mast cells in dominant tolerance
Published in Current opinion in organ transplantation (01-08-2009)“…The role of regulatory T cells (Treg) in peripheral tolerance has been studied extensively in transplantation research. Recently, mast cells have been shown to…”
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Journal Article -
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Lipopolysaccharide-Induced Suppression of Airway Th2 Responses Does Not Require IL-12 Production by Dendritic Cells
Published in The Journal of immunology (1950) (01-10-2003)“…The prevalence of atopic asthma, a Th2-dependent disease, is reaching epidemic proportions partly due to improved hygiene in industrialized countries. There is…”
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Airway Eosinophils Accumulate in the Mediastinal Lymph Nodes but Lack Antigen-Presenting Potential for Naive T Cells
Published in The Journal of immunology (1950) (01-10-2003)“…Asthma is characterized by infiltration of the airway wall with eosinophils. Although eosinophils are considered to be effector cells, recent studies have…”
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Studying mast cells in peripheral tolerance by using a skin transplantation model
Published in Methods in molecular biology (Clifton, N.J.) (01-01-2015)“…Mast cells (MCs) play an important role in both inflammatory and immunosuppressive responses [1]. The importance of MCs in maintaining peripheral tolerance was…”
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Allergen-induced accumulation of airway dendritic cells is supported by an increase in CD31hiLy-6Cneg bone marrow precursors in a mouse model of asthma
Published in Blood (15-11-2002)“…Airway dendritic cells (DCs) are held responsible for inducing sensitization to inhaled antigen, leading to eosinophilic airway inflammation, typical of…”
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Journal Article -
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Mast Cell Degranulation Breaks Peripheral Tolerance
Published in American journal of transplantation (01-10-2009)“…Mast cells (MC) have been shown to mediate regulatory T‐cell (Treg)‐dependent, peripheral allograft tolerance in both skin and cardiac transplants…”
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Programmed death 1 ligand signaling regulates the generation of adaptive Foxp3 super(+)CD4 super(+) regulatory T cells
Published in Proceedings of the National Academy of Sciences - PNAS (08-07-2008)“…Although mature dendritic cells (DCs) are potent initiators of adaptive immune response, immature steady-state DCs contribute to immune tolerance. In this…”
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Journal Article -
17
Programmed death 1 ligand signaling regulates the generation of adaptive Foxp3 ^sup +^CD4^sup +^ regulatory T cells
Published in Proceedings of the National Academy of Sciences - PNAS (08-07-2008)“…Although mature dendritic cells (DCs) are potent initiators of adaptive immune response, immature steady-state DCs contribute to immune tolerance. In this…”
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Journal Article -
18
Regulation of peripheral tolerance by mast cells
Published 01-01-2010“…Mast cells (MC) have until recently been regarded as pro-inflammatory, however this view changed with the observation that the absence of MC impairs the…”
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Dissertation -
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Allergen-induced accumulation of airway dendritic cells is supported by an increase in CD31(hi)Ly-6C(neg) bone marrow precursors in a mouse model of asthma
Published in Blood (15-11-2002)“…Airway dendritic cells (DCs) are held responsible for inducing sensitization to inhaled antigen, leading to eosinophilic airway inflammation, typical of…”
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Journal Article -
20
Regulation of peripheral tolerance by mast cells
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Dissertation