Search Results - "de Vries, Rory D."
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1
Measles Virus Host Invasion and Pathogenesis
Published in Viruses (28-07-2016)“…Measles virus is a highly contagious negative strand RNA virus that is transmitted via the respiratory route and causes systemic disease in previously…”
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2
Measles skin rash: Infection of lymphoid and myeloid cells in the dermis precedes viral dissemination to the epidermis
Published in PLoS pathogens (08-10-2020)“…Measles is characterized by fever and a maculopapular skin rash, which is accompanied by immune clearance of measles virus (MV)-infected cells…”
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3
Morbillivirus infections: an introduction
Published in Viruses (12-02-2015)“…Research on morbillivirus infections has led to exciting developments in recent years. Global measles vaccination coverage has increased, resulting in a…”
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Modified vaccinia virus ankara (MVA) as production platform for vaccines against influenza and other viral respiratory diseases
Published in Viruses (17-07-2014)“…Respiratory viruses infections caused by influenza viruses, human parainfluenza virus (hPIV), respiratory syncytial virus (RSV) and coronaviruses are an…”
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5
Delineating morbillivirus entry, dissemination and airborne transmission by studying in vivo competition of multicolor canine distemper viruses in ferrets
Published in PLoS pathogens (08-05-2017)“…Identification of cellular receptors and characterization of viral tropism in animal models have vastly improved our understanding of morbillivirus…”
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6
mSphere of Influence: Understanding Virus-Host Interactions Requires a Multifaceted Approach
Published in mSphere (25-03-2020)“…Rory de Vries works in the field of viral pathogenesis and focuses on interactions between respiratory viruses (or corresponding vaccines) and the host immune…”
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Modeling the measles paradox reveals the importance of cellular immunity in regulating viral clearance
Published in PLoS pathogens (28-12-2018)“…Measles virus (MV) is a highly contagious member of the Morbillivirus genus that remains a major cause of childhood mortality worldwide. Although infection…”
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Analyzing the immunogenicity of bivalent booster vaccinations in healthcare workers: The SWITCH ON trial protocol
Published in Frontiers in immunology (29-11-2022)“…Vaccination against coronavirus disease 2019 (COVID-19) has contributed greatly to providing protection against severe disease, thereby reducing hospital…”
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A prominent role for DC-SIGN+ dendritic cells in initiation and dissemination of measles virus infection in non-human primates
Published in PloS one (05-12-2012)“…Measles virus (MV) is a highly contagious virus that is transmitted by aerosols. During systemic infection, CD150(+) T and B lymphocytes in blood and lymphoid…”
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Intranasal fusion inhibitory lipopeptide prevents direct-contact SARS-CoV-2 transmission in ferrets
Published in Science (American Association for the Advancement of Science) (26-03-2021)“…Containment of the COVID-19 pandemic requires reducing viral transmission. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is initiated…”
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11
Low levels of monkeypox virus-neutralizing antibodies after MVA-BN vaccination in healthy individuals
Published in Nature medicine (01-01-2023)“…In July 2022, the ongoing monkeypox (MPX) outbreak was declared a public health emergency of international concern. Modified vaccinia Ankara—Bavarian Nordic…”
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Infection of ferrets with wild type-based recombinant canine distemper virus overwhelms the immune system and causes fatal systemic disease
Published in mSphere (24-08-2023)“…Canine distemper virus (CDV) causes systemic infection resulting in severe and often fatal disease in a large spectrum of animal host species. The virus is…”
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Inoculation of raccoons with a wild-type-based recombinant canine distemper virus results in viremia, lymphopenia, fever, and widespread histological lesions
Published in mSphere (24-08-2023)“…Raccoons are naturally susceptible to canine distemper virus (CDV) infection and can be a potential source of spill-over events. CDV is a highly contagious…”
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14
Sustained Replication of Synthetic Canine Distemper Virus Defective Genomes In Vitro and In Vivo
Published in mSphere (27-10-2021)“…Defective interfering (DI) genomes restrict viral replication and induce type I interferon. Since DI genomes have been proposed as vaccine adjuvants or…”
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Developing Universal Influenza Vaccines: Hitting the Nail, Not Just on the Head
Published in Vaccines (Basel) (26-03-2015)“…Influenza viruses have a huge impact on public health. Current influenza vaccines need to be updated annually and protect poorly against antigenic drift…”
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Needle-free delivery of measles virus vaccine to the lower respiratory tract of non-human primates elicits optimal immunity and protection
Published in npj vaccines (01-08-2017)“…Needle-free measles virus vaccination by aerosol inhalation has many potential benefits. The current standard route of vaccination is subcutaneous injection,…”
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Studies into the mechanism of measles-associated immune suppression during a measles outbreak in the Netherlands
Published in Nature communications (23-11-2018)“…Measles causes a transient immune suppression, leading to increased susceptibility to opportunistic infections. In experimentally infected non-human primates…”
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ADCC: An underappreciated correlate of cross-protection against influenza?
Published in Frontiers in immunology (22-02-2023)“…In this short review, we summarized the results obtained with an assay to detect influenza virus-specific antibodies that mediate ADCC, which was developed and…”
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Measles immune suppression: functional impairment or numbers game?
Published in PLoS pathogens (01-12-2014)“… Resolution of MV infection is associated with increased lymphoproliferation [8], [24] and enlargement of lymph nodes [13]. [...]the immune system efficiently…”
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The Importance of Measuring SARS-CoV-2-Specific T-Cell Responses in an Ongoing Pandemic
Published in Pathogens (Basel) (22-06-2023)“…Neutralizing antibodies are considered a correlate of protection against SARS-CoV-2 infection and severe COVID-19, although they are not the only contributing…”
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