Search Results - "de Vries, Natasja L."

The Immunogenicity of Colorectal Cancer in Relation to Tumor Development and Treatment by de Vries, Natasja L, Swets, Marloes, Vahrmeijer, Alexander L, Hokland, Marianne, Kuppen, Peter J K

“…Although most cancer types have been viewed as immunologically silent until recently, it has become increasingly clear that the immune system plays key roles…”
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High-dimensional cytometric analysis of colorectal cancer reveals novel mediators of antitumour immunity by de Vries, Natasja L, van Unen, Vincent, Ijsselsteijn, Marieke E, Abdelaal, Tamim, van der Breggen, Ruud, Farina Sarasqueta, Arantza, Mahfouz, Ahmed, Peeters, Koen C M J, Höllt, Thomas, Lelieveldt, Boudewijn P F, Koning, Frits, de Miranda, Noel F C C

“…A comprehensive understanding of anticancer immune responses is paramount for the optimal application and development of cancer immunotherapies. We unravelled…”
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Unraveling the Complexity of the Cancer Microenvironment With Multidimensional Genomic and Cytometric Technologies by de Vries, Natasja L, Mahfouz, Ahmed, Koning, Frits, de Miranda, Noel F C C

“…Cancers are characterized by extensive heterogeneity that occurs intratumorally, between lesions, and across patients. To study cancer as a complex biological…”
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CD163 as a Biomarker in Colorectal Cancer: The Expression on Circulating Monocytes and Tumor-Associated Macrophages, and the Soluble Form in the Blood by Krijgsman, Daniëlle, De Vries, Natasja L, Andersen, Morten N, Skovbo, Anni, Tollenaar, Rob A E M, Møller, Holger J, Hokland, Marianne, Kuppen, Peter J K

“…The macrophage-associated molecule CD163 has been reported as a prognostic biomarker in different cancer types, but its role in colorectal cancer (CRC) is…”
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Neoantigen-specific immunity in low mutation burden colorectal cancers of the consensus molecular subtype 4 by van den Bulk, Jitske, Verdegaal, Els M E, Ruano, Dina, Ijsselsteijn, Marieke E, Visser, Marten, van der Breggen, Ruud, Duhen, Thomas, van der Ploeg, Manon, de Vries, Natasja L, Oosting, Jan, Peeters, Koen C M J, Weinberg, Andrew D, Farina-Sarasqueta, Arantza, van der Burg, Sjoerd H, de Miranda, Noel F C C

“…The efficacy of checkpoint blockade immunotherapies in colorectal cancer is currently restricted to a minority of patients diagnosed with mismatch…”
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Local and systemic immune profiles of human pancreatic ductal adenocarcinoma revealed by single-cell mass cytometry by Brouwer, Thomas P, de Vries, Natasja L, Abdelaal, Tamim, Krog, Ricki T, Li, Zheng, Ruano, Dina, Fariña, Arantza, Lelieveldt, Boudewijn P F, Morreau, Hans, Bonsing, Bert A, Vahrmeijer, Alexander L, Koning, Frits, de Miranda, Noel F C C

“…BackgroundPancreatic ductal adenocarcinoma (PDAC) is a highly lethal malignancy in need of effective (immuno)therapeutic treatment strategies. For the optimal…”
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γδ T cells are effectors of immunotherapy in cancers with HLA class I defects by de Vries, Natasja L., van de Haar, Joris, Veninga, Vivien, Chalabi, Myriam, Ijsselsteijn, Marieke E., van der Ploeg, Manon, van den Bulk, Jitske, Ruano, Dina, van den Berg, Jose G., Haanen, John B., Zeverijn, Laurien J., Geurts, Birgit S., de Wit, Gijs F., Battaglia, Thomas W., Gelderblom, Hans, Verheul, Henk M. W., Schumacher, Ton N., Wessels, Lodewyk F. A., Koning, Frits, de Miranda, Noel F. C. C., Voest, Emile E.

“…DNA mismatch repair-deficient (MMR-d) cancers present an abundance of neoantigens that is thought to explain their exceptional responsiveness to immune…”
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Characterization of circulating T-, NK-, and NKT cell subsets in patients with colorectal cancer: the peripheral blood immune cell profile by Krijgsman, Daniëlle, de Vries, Natasja L., Skovbo, Anni, Andersen, Morten N., Swets, Marloes, Bastiaannet, Esther, Vahrmeijer, Alexander L., van de Velde, Cornelis J. H., Heemskerk, Mirjam H. M., Hokland, Marianne, Kuppen, Peter J. K.

“…Objective As the development and progression of colorectal cancer (CRC) are known to be affected by the immune system, cell subsets such as T cells, natural…”
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The effects of tumor resection and adjuvant therapy on the peripheral blood immune cell profile in patients with colon carcinoma by Krijgsman, Daniëlle, De Vries, Natasja L., Andersen, Morten N., Skovbo, Anni, Tollenaar, Rob A. E. M., Bastiaannet, Esther, Kuppen, Peter J. K., Hokland, Marianne

“…Objective The subset distribution and immunophenotype of circulating immune cells (“peripheral blood immune cell profile”) may reflect tumor development and…”
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