Search Results - "de Vreede, Geert"
-
1
PTP10D-mediated cell competition is not obligately required for elimination of polarity-deficient clones
Published in Biology open (01-11-2022)“…Animal organs maintain tissue integrity and ensure removal of aberrant cells through several types of surveillance mechanisms. One prominent example is the…”
Get full text
Journal Article -
2
The Scribble module regulates retromer-dependent endocytic trafficking during epithelial polarization
Published in Development (Cambridge) (01-07-2014)“…Scribble (Scrib) module proteins are major regulators of cell polarity, but how they influence membrane traffic is not known. Endocytosis is also a key…”
Get full text
Journal Article -
3
Epithelial monitoring via ligand-receptor segregation ensures malignant cell elimination
Published in Science (American Association for the Advancement of Science) (14-04-2022)“…Animals have evolved mechanisms, such as cell competition, to remove dangerous or nonfunctional cells from a tissue. Tumor Necrosis Factor signaling can…”
Get full text
Journal Article -
4
Epithelial monitoring through ligand-receptor segregation ensures malignant cell elimination
Published in Science (American Association for the Advancement of Science) (15-04-2022)“…Animals have evolved mechanisms, such as cell competition, to remove dangerous or nonfunctional cells from a tissue. Tumor necrosis factor signaling can…”
Get full text
Journal Article -
5
Cell shape and Wnt signaling redundantly control the division axis of C. elegans epithelial stem cells
Published in Development (Cambridge) (15-10-2011)“…Tissue-specific stem cells combine proliferative and asymmetric divisions to balance self-renewal with differentiation. Tight regulation of the orientation and…”
Get full text
Journal Article -
6
A Drosophila Tumor Suppressor Gene Prevents Tonic TNF Signaling through Receptor N-Glycosylation
Published in Developmental cell (04-06-2018)“…Drosophila tumor suppressor genes have revealed molecular pathways that control tissue growth, but mechanisms that regulate mitogenic signaling are far from…”
Get full text
Journal Article -
7
The F-box protein Slmb restricts the activity of aPKC to polarize epithelial cells
Published in Development (Cambridge) (01-08-2014)“…The Par-3/Par-6/aPKC complex is the primary determinant of apical polarity in epithelia across animal species, but how the activity of this complex is…”
Get full text
Journal Article