Search Results - "de Vree, J.Marleen L."

The wide spectrum of multidrug resistance 3 deficiency: From neonatal cholestasis to cirrhosis of adulthood by Jacquemin, Emmanuel, De Vree, J. Marleen L., Cresteil, Danièle, Sokal, Etienne M., Sturm, Ekkehard, Dumont, Micheline, Scheffer, George L., Paul, Marianne, Burdelski, Martin, Bosma, Piter J., Bernard, Olivier, Hadchouel, Michelle, Oude Elferink, Ronald P.J.

“…Background & Aims: We have specified the features of progressive familial intrahepatic cholestasis type 3 and investigated in 31 patients whether a defect of…”
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Correction of liver disease by hepatocyte transplantation in a mouse model of progressive familial intrahepatic cholestasis by De Vree, J.Marleen L., Ottenhoff, Roel, Bosma, Piter J., Smith, Alexander J., Aten, Jan, Oude Elferink, Ronald P.J.

“…Background & Aims: Patients with progressive familial intrahepatic cholestasis (PFIC) type 3 have a mutation in the MDR3 gene, encoding the hepatocanalicular…”
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FIC1, the protein affected in two forms of hereditary cholestasis, is localized in the cholangiocyte and the canalicular membrane of the hepatocyte by Eppens, Elaine F., van Mil, Saskia W.C., de Vree, J.Marleen L., Mok, Kam S., Juijn, Jenneke A., Oude Elferink, Ronald P.J., Berger, Ruud, Houwen, Roderick H.J., Klomp, Leo W.J.

“…Background/Aims : FIC1 (familial intrahepatic cholestasis 1) is affected in two clinically distinct forms of hereditary cholestasis, namely progressive…”
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Dietary cholesterol does not normalize low plasma cholesterol levels but induces hyperbilirubinemia and hypercholanemia in Mdr2 P-glycoprotein-deficient mice by Voshol, Peter J, Koopen, Nynke R, de Vree, J.Marleen L, Havinga, Rick, Princen, Hans M.G, Oude Elferink, Ronald P.J, Groen, Albert K, Kuipers, Folkert

“…Background/Aims : Mdr2 P-glycoprotein deficiency in mice ( Mdr2 (−/−) ) leads to formation of cholesterol/cholesterol-depleted bile and reduced plasma HDL…”
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