Search Results - "de Vos, Willem M."

Next-Generation Beneficial Microbes: The Case of Akkermansia muciniphila by Cani, Patrice D, de Vos, Willem M

“…Metabolic disorders associated with obesity and cardiometabolic disorders are worldwide epidemic. Among the different environmental factors, the gut microbiota…”
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Early life colonization of the human gut: microbes matter everywhere by Korpela, Katri, de Vos, Willem M.

“…[Display omitted] •The intestinal microbiota follows a common successional pattern in early life.•Particular bacterial taxa are mainly transmitted from the…”
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Healthy human gut phageome by Manrique, Pilar, Bolduc, Benjamin, Walk, Seth T., van der Oost, John, de Vos, Willem M., Young, Mark J.

“…The role of bacteriophages in influencing the structure and function of the healthy human gut microbiome is unknown. With few exceptions, previous studies have…”
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Intestinal microbiome landscaping: insight in community assemblage and implications for microbial modulation strategies by Shetty, Sudarshan A., Hugenholtz, Floor, Lahti, Leo, Smidt, Hauke, de Vos, Willem M.

“…Abstract High individuality, large complexity and limited understanding of the mechanisms underlying human intestinal microbiome function remain the major…”
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A purified membrane protein from Akkermansia muciniphila or the pasteurized bacterium improves metabolism in obese and diabetic mice by Plovier, Hubert, Everard, Amandine, Druart, Céline, Depommier, Clara, Van Hul, Matthias, Geurts, Lucie, Chilloux, Julien, Ottman, Noora, Duparc, Thibaut, Lichtenstein, Laeticia, Myridakis, Antonis, Delzenne, Nathalie M, Klievink, Judith, Bhattacharjee, Arnab, van der Ark, Kees C H, Aalvink, Steven, Martinez, Laurent O, Dumas, Marc-Emmanuel, Maiter, Dominique, Loumaye, Audrey, Hermans, Michel P, Thissen, Jean-Paul, Belzer, Clara, de Vos, Willem M, Cani, Patrice D

“…Akkermansia muciniphila , a member of the gut microbiome, has been shown to improve metabolism in mice. Here it is reported that its pasteurization further…”
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Homeostasis of the gut barrier and potential biomarkers by Wells, Jerry M, Brummer, Robert J, Derrien, Muriel, MacDonald, Thomas T, Troost, Freddy, Cani, Patrice D, Theodorou, Vassilia, Dekker, Jan, Méheust, Agnes, de Vos, Willem M, Mercenier, Annick, Nauta, Arjen, Garcia-Rodenas, Clara L

“…The gut barrier plays a crucial role by spatially compartmentalizing bacteria to the lumen through the production of secreted mucus and is fortified by the…”
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Microbial Metabolic Networks at the Mucus Layer Lead to Diet-Independent Butyrate and Vitamin B12 Production by Intestinal Symbionts by Belzer, Clara, Chia, Loo Wee, Aalvink, Steven, Chamlagain, Bhawani, Piironen, Vieno, Knol, Jan, de Vos, Willem M

“…Akkermansia muciniphila has evolved to specialize in the degradation and utilization of host mucus, which it may use as the sole source of carbon and nitrogen…”
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Action and function of Akkermansia muciniphila in microbiome ecology, health and disease by Ottman, Noora, Geerlings, Sharon Y., Aalvink, Steven, de Vos, Willem M., Belzer, Clara

“…The discovery of Akkermansia muciniphila has opened new avenues for the use of this abundant intestinal symbiont in next generation therapeutic products, as…”
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The Effect of Psyllium Husk on Intestinal Microbiota in Constipated Patients and Healthy Controls by Jalanka, Jonna, Major, Giles, Murray, Kathryn, Singh, Gulzar, Nowak, Adam, Kurtz, Caroline, Silos-Santiago, Inmaculada, Johnston, Jeffrey M, de Vos, Willem M, Spiller, Robin

“…Psyllium is a widely used treatment for constipation. It traps water in the intestine increasing stool water, easing defaecation and altering the colonic…”
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Pili-like proteins of Akkermansia muciniphila modulate host immune responses and gut barrier function by Ottman, Noora, Reunanen, Justus, Meijerink, Marjolein, Pietilä, Taija E, Kainulainen, Veera, Klievink, Judith, Huuskonen, Laura, Aalvink, Steven, Skurnik, Mikael, Boeren, Sjef, Satokari, Reetta, Mercenier, Annick, Palva, Airi, Smidt, Hauke, de Vos, Willem M, Belzer, Clara

“…Gut barrier function is key in maintaining a balanced response between the host and its microbiome. The microbiota can modulate changes in gut barrier as well…”
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Intestinal epithelial N-acylphosphatidylethanolamine phospholipase D links dietary fat to metabolic adaptations in obesity and steatosis by Everard, Amandine, Plovier, Hubert, Rastelli, Marialetizia, Van Hul, Matthias, de Wouters d’Oplinter, Alice, Geurts, Lucie, Druart, Céline, Robine, Sylvie, Delzenne, Nathalie M., Muccioli, Giulio G., de Vos, Willem M., Luquet, Serge, Flamand, Nicolas, Di Marzo, Vincenzo, Cani, Patrice D.

“…Variations in N -acylethanolamines (NAE) levels are associated with obesity and metabolic comorbidities. Their role in the gut remains unclear. Therefore, we…”
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Bowel Biofilms: Tipping Points between a Healthy and Compromised Gut? by Tytgat, Hanne L.P., Nobrega, Franklin L., van der Oost, John, de Vos, Willem M.

“…Bacterial communities are known to impact human health and disease. Mixed species biofilms, mostly pathogenic in nature, have been observed in dental and…”
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Significant Correlation Between the Infant Gut Microbiome and Rotavirus Vaccine Response in Rural Ghana by Harris, Vanessa C., Armah, George, Fuentes, Susana, Korpela, Katri E., Parashar, Umesh, Victor, John C., Tate, Jacqueline, de Weerth, Carolina, Giaquinto, Carlo, Wiersinga, Willem Joost, Lewis, Kristen D. C., de Vos, Willem M.

“…Background. Rotavirus (RV) is the leading cause of diarrhea-related death in children worldwide and 95% of RV-associated deaths occur in Africa and Asia where…”
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Next Generation Prokaryotic Engineering: The CRISPR-Cas Toolkit by Mougiakos, Ioannis, Bosma, Elleke F, de Vos, Willem M, van Kranenburg, Richard, van der Oost, John

“…The increasing demand for environmentally friendly production processes of green chemicals and fuels has stimulated research in microbial metabolic…”
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Variation of mucin adhesion, cell surface characteristics, and molecular mechanisms among Lactobacillus plantarum isolated from different habitats by Buntin, Nirunya, de Vos, Willem M., Hongpattarakere, Tipparat

“…The adhesion ability to mucin varied greatly among 18 Lactobacillus plantarum isolates depending on their isolation habitats. Such ability remained at high…”
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Probiotic supplementation restores normal microbiota composition and function in antibiotic-treated and in caesarean-born infants by Korpela, Katri, Salonen, Anne, Vepsäläinen, Outi, Suomalainen, Marjo, Kolmeder, Carolin, Varjosalo, Markku, Miettinen, Sini, Kukkonen, Kaarina, Savilahti, Erkki, Kuitunen, Mikael, de Vos, Willem M

“…Infants born by caesarean section or receiving antibiotics are at increased risk of developing metabolic, inflammatory and immunological diseases, potentially…”
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Akkermansia muciniphila uses human milk oligosaccharides to thrive in the early life conditions in vitro by Kostopoulos, Ioannis, Elzinga, Janneke, Ottman, Noora, Klievink, Jay T., Blijenberg, Bernadet, Aalvink, Steven, Boeren, Sjef, Mank, Marko, Knol, Jan, de Vos, Willem M., Belzer, Clara

“…Akkermansia muciniphila is a well-studied anaerobic bacterium specialized in mucus degradation and associated with human health. Because of the structural…”
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Critically ill patients demonstrate large interpersonal variation in intestinal microbiota dysregulation: a pilot study by Lankelma, Jacqueline M., van Vught, Lonneke A., Belzer, Clara, Schultz, Marcus J., van der Poll, Tom, de Vos, Willem M., Wiersinga, W. Joost

“…Purpose The intestinal microbiota has emerged as a virtual organ with essential functions in human physiology. Antibiotic-induced disruption of the microbiota…”
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Harnessing the power of microbial autotrophy by Claassens, Nico J., Sousa, Diana Z., dos Santos, Vitor A. P. Martins, de Vos, Willem M., van der Oost, John

“…Key Points Autotrophic microorganisms have the potential to efficiently convert CO 2 into a wide range of chemicals and biofuels, which is a promising…”
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Intestinal microbiota in healthy adults: temporal analysis reveals individual and common core and relation to intestinal symptoms by Jalanka-Tuovinen, J, Vos, W.M. de

“…While our knowledge of the intestinal microbiota during disease is accumulating, basic information of the microbiota in healthy subjects is still scarce. The…”
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