Search Results - "de Vera, Nuria"
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Quantitative imaging of microtubule alteration as an early marker of axonal degeneration after ischemia in neurons
Published in Biophysical journal (05-03-2013)“…Neuronal death can be preceded by progressive dysfunction of axons. Several pathological conditions such as ischemia can disrupt the neuronal cytoskeleton…”
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2
Lack of the Histone Deacetylase SIRT1 Leads to Protection against Endoplasmic Reticulum Stress through the Upregulation of Heat Shock Proteins
Published in International journal of molecular sciences (01-03-2024)“…Histone deacetylase SIRT1 represses gene expression through the deacetylation of histones and transcription factors and is involved in the protective cell…”
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3
Modified C-Reactive Protein Is Expressed by Stroke Neovessels and Is a Potent Activator of Angiogenesis In Vitro
Published in Brain pathology (Zurich, Switzerland) (01-01-2010)“…Native C‐reactive protein (nCRP) is a pentameric oligo‐protein and an acute phase reactant whose serum expression is increased in patients with inflammatory…”
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4
Spermine induces cell death in cultured human embryonic cerebral cortical neurons through N-methyl-D-aspartate receptor activation
Published in Journal of neuroscience research (01-03-2008)“…The polyamines putrescine, spermidine, and spermine play important roles in cell proliferation, differentiation, and modulation of ion channel receptors…”
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5
Polyamines in the basal ganglia of human brain. Influence of aging and degenerative movement disorders
Published in Neuroscience letters (18-05-2001)“…The distribution of polyamines in the human basal ganglia was examined, using dansyl-derivatives and high pressure liquid chromatography with fluorimetric…”
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6
Identification of pro-angiogenic markers in blood vessels from stroked-affected brain tissue using laser-capture microdissection
Published in BMC genomics (17-03-2009)“…Angiogenesis correlates with patient survival following acute ischaemic stroke, and survival of neurons is greatest in tissue undergoing angiogenesis…”
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7
RGD-based cell ligands for cell-targeted drug delivery act as potent trophic factors
Published in Nanomedicine (01-11-2012)“…Abstract Integrin-binding, Arg-Gly-Asp (RGD)–containing peptides are the most widely used agents to deliver drugs, nanoparticles, and imaging agents. Although…”
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8
In vitro and in vivo activation of astrocytes by amyloid-beta is potentiated by pro-oxidant agents
Published in Journal of Alzheimer's disease (01-01-2010)“…Alzheimer's disease (AD) is a devastating age-related neurodegenerative disease. Age is the main risk factor for sporadic AD, which is the most prevalent type…”
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Type 1 cannabinoid receptor mapping with [18F]MK-9470 PET in the rat brain after quinolinic acid lesion: a comparison to dopamine receptors and glucose metabolism
Published in European journal of nuclear medicine and molecular imaging (01-12-2010)“…Purpose Several lines of evidence imply early alterations in metabolic, dopaminergic and endocannabinoid neurotransmission in Huntington’s disease (HD). Using…”
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10
Silent information regulator 1 protects the liver against ischemia-reperfusion injury: implications in steatotic liver ischemic preconditioning
Published in Transplant international (01-05-2014)“…Ischemia-reperfusion (IR) injury is an important problem in liver surgery especially when steatosis is present. Ischemic preconditioning (PC) is the only…”
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11
A complementary diffusion tensor imaging (DTI)-histological study in a model of Huntington's disease
Published in Neurobiology of aging (01-05-2012)“…Abstract In vivo diffusion tensor imaging (DTI) was performed on the quinolinic acid (QUIN) rat model of Huntington's disease, together with behavioral…”
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12
Putrescine as a marker of the effects of 2-chloropropionic acid in the rat brain
Published in Neuroscience letters (27-05-2004)“…The neurotoxin 2-chloropropionic acid (2CPA, 750 mg/kg, per os) induces ataxia in rats causing neuropathological changes (necrosis and edema) localized mainly…”
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13
Lesion of substantia nigra pars compacta by the GluR5 agonist ATPA
Published in Brain research (15-11-2002)“…Dopamine (DA) released by substantia nigra pars compacta (SNc) neurons is a key regulator of motor activity. A deficiency in the striatum DA content due to SNc…”
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14
Extracellular putrescine content after acute excitotoxic brain damage in the rat
Published in Neuroscience letters (13-09-2002)“…We examined the effects of the local infusion of kainic acid (KA), by reverse dialysis in the rat striatum, on the concentration of polyamines in the…”
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15
Seizures and neuronal damage induced in the rat by activation of group I metabotropic glutamate receptors with their selective agonist 3,5-dihydroxyphenylglycine
Published in Journal of neuroscience research (01-02-1998)“…While it is well documented that the overactivation of ionotropic glutamate receptors leads to seizures and excitotoxic injury, little is known about the role…”
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Cerebral distribution of polyamines in kainic acid-induced models of status epilepticus and ataxia in rats. Overproduction of putrescine and histological damage
Published in European neuropsychopharmacology (01-10-2002)“…We study the brain regional distribution of putrescine after excitotoxic damage. After status epilepticus induced by kainic acid (9 mg/kg, i.p.) we found an…”
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Motor depressant effects of systemically administered polyamines in mice: involvement of central NMDA receptors
Published in European journal of pharmacology (30-12-1996)“…The systemic administration of polyamines (s.c.) produced a dose-dependent motor depression. With high doses the depressant effect was long-lasting and the…”
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18
Long-term effects of status epilepticus induced by kainic acid on hippocampal polyamines
Published in Neuroreport (30-03-1998)“…PUTRESCINE has been suggested to have an inhibitory effect on the excitability of the central nervous system. In the present study we found that 2 and 3 weeks…”
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Changes in brain putrescine concentration associated with nonconvulsant behavioral patterns induced by systemic N-methyl-D-aspartate injection
Published in Molecular and chemical neuropathology (01-04-1997)“…The relationship between the behavioral effects and motor activity induced by N-methyl-D-aspartate (NMDA) (150 mg/kg, ip) and brain polyamine concentration was…”
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