Validation of PI-RADS v.2 for prostate cancer diagnosis with MRI at 3T using an external phased-array coil

Purpose To date, few studies have validated the Prostate Imaging Reporting and Data System Version 2 (PI‐RADS v. 2) for the diagnosis of prostate cancer. Our aim was to validate PI‐RADS v.2 using 3 Tesla (T) MRI. Materials and Methods This is a retrospective study of 54 consecutive patients who unde...

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Bibliographic Details
Published in:	Journal of magnetic resonance imaging Vol. 44; no. 5; pp. 1354 - 1359
Main Authors:	Baldisserotto, Matteo, Neto, Eurico J. Dornelles, Carvalhal, Gustavo, de Toledo, Aloyso F., de Almeida, Clovis M., Cairoli, Carlos E.D., de Silva, Daniel O., Carvalhal, Eduardo, Paganin, Ricardo P., Agra, Alexandre, de Santos, Francisco S., Noronha, Jorge A.P.
Format:	Journal Article
Language:	English
Published:	United States Blackwell Publishing Ltd 01-11-2016 Wiley Subscription Services, Inc
Subjects:	Accuracy Aged Aged, 80 and over Agreements Cancer Confidence intervals Diagnosis Diagnostic systems Equipment Design Humans Image Interpretation, Computer-Assisted - instrumentation Image Interpretation, Computer-Assisted - standards Internationality Magnetic resonance imaging Magnetic Resonance Imaging - instrumentation Magnetic Resonance Imaging - standards Male Middle Aged Patients Practice Guidelines as Topic Prostate cancer Prostatic Neoplasms - diagnostic imaging Prostatic Neoplasms - pathology Radiation Dosage Radiology Information Systems - standards Reproducibility of Results scoring method Sensitivity and Specificity Transducers - standards validation studies magnetic resonance imaging prostate cancer scoring method validation studies
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Summary:	Purpose To date, few studies have validated the Prostate Imaging Reporting and Data System Version 2 (PI‐RADS v. 2) for the diagnosis of prostate cancer. Our aim was to validate PI‐RADS v.2 using 3 Tesla (T) MRI. Materials and Methods This is a retrospective study of 54 consecutive patients who underwent 3T MRI with a body‐array coil for diagnostic confirmation of prostate cancer or cancer staging between June 2013 and June 2015. Sensitivity, specificity, and agreement were calculated based on a criterion of PI‐RADS score = 3. Inter‐examiner agreement was determined by the weighted kappa statistic. Results Histological findings were positive for cancer in 33 patients and negative in 21 patients. Considering a PI‐RADS score of 3 as positive for cancer, the accuracy of each reader was 85.20% and 70.40%, respectively, and agreement coefficients were κ = 0.69 and κ = 0.35. Considering PI‐RADS 3 as absence of cancer, the accuracy of each reader was 77.80% and 77.80%, respectively, and agreement was κ = 0.55 and κ = 0.54. Inter‐reader agreement was moderate/good (weighted κ = 0.53; 95% confidence interval: 0.39–0.66; P = 0.038). Conclusion High accuracy was obtained for the diagnosis of prostate cancer using 3T MRI with a body coil and the PI‐RADS v.2 score. J. Magn. Reson. Imaging 2016;44:1354–1359.
Bibliography:	istex:1B3B8C1066A580A47DE31CF8F92C9D7C0321DB3F ArticleID:JMRI25284 ark:/67375/WNG-WBD6B6SQ-M ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23
ISSN:	1053-1807 1522-2586
DOI:	10.1002/jmri.25284