Search Results - "de Souza Filho, José D"
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New 99mTc-Labeled Digitoxigenin Derivative for Cancer Cell Identification
Published in ACS omega (24-12-2019)“…In recent years, cardiac glycosides (CGs) have been investigated as potential antiviral and anticancer drugs. Digitoxigenin (DIG) and other CGs have been shown…”
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2
On the search for potential anti-Trypanosoma cruzi drugs: Synthesis and biological evaluation of 2-hydroxy-3-methylamino and 1,2,3-triazolic naphthoquinoidal compounds obtained by click chemistry reactions
Published in European journal of medicinal chemistry (01-06-2012)“…Five 2-hydroxy-3-substituted-aminomethyl naphthoquinones, nine 1,2,3-triazolic para-naphthoquinones, five nor-β-lapachone-based 1,2,3-triazoles, and several…”
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3
Anti-inflammatory and antinociceptive activities of Campomanesia adamantium
Published in Journal of ethnopharmacology (09-01-2013)“…Campomanesia species are used in folk medicine as anti-inflammatory, anti-rheumatic, anti-diarrheal and hypocholesterolemic. The present study investigated the…”
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4
Glycotriazole-peptides derived from the peptide HSP1: synergistic effect of triazole and saccharide rings on the antifungal activity
Published in Amino acids (01-08-2017)“…This work proposes a strategy that uses solid-phase peptide synthesis associated with copper(I)-catalyzed azide alkyne cycloaddition reaction to promote the…”
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5
NMR-Based Metabolomic Screening for Metabolites Associated with Resistance to Meloidogyne javanica in Annona muricata Roots
Published in Journal of the Brazilian Chemical Society (01-06-2019)“…The resistance of Annona muricata roots to the nematode Meloidogyne javanica was investigated by nuclear magnetic resonance (NMR)-based metabolomics in…”
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6
Synthesis by Click Reactions and Antiplasmodial Activity of Lupeol 1,2,3-Triazole Derivatives
Published in Journal of the Brazilian Chemical Society (01-10-2017)“…Lupeol, a triterpene frequently found in Asteraceae plant species, showed moderate to low activity in different strains of Plasmodium falciparum, the most…”
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7
An efficient synthesis of D-galactose-based multivalent neoglycoconjugates
Published in Journal of the Brazilian Chemical Society (01-06-2012)“…In this work, the synthesis of dimeric, trimeric and tetrameric D-galactose-based neoglycoconjugates is reported. The monosaccharide ligand was prepared in 5…”
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8
A macrolactone from benzo[ a]phenazine with potent activity against Mycobacterium tuberculosis
Published in European journal of medicinal chemistry (01-05-2009)“…We report here an alternative to the MCPBA or ozonolysis-based oxidation methods of quinoxaline-featuring compounds prepared from beta-lapachones. The use of…”
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9
Enhancing the solubility and permeability of the diuretic drug furosemide via multicomponent crystal forms
Published in International journal of pharmaceutics (25-09-2020)“…[Display omitted] •Two multicomponent crystal forms of furosemide were prepared and elucidated.•A solid-state study was performed to correlate with…”
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10
Plant growth regulation activity of steviol and derivatives
Published in Phytochemistry (Oxford) (01-05-2008)“…Kaurenes 3– 5 and beyeranes 6– 10 were prepared and tested for plant growth regulation activity using lettuce hypocotyl and barley aleurone bioassays. Steviol…”
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11
Two new oleanane saponins from Chiococca alba (L.) Hitch
Published in Journal of the Brazilian Chemical Society (2009)“…Two triterpene saponins were isolated from the ethanolic extract of the roots of Chiococca alba (L.) Hitch (Rubiaceae). Their structures were determined by ¹H…”
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12
HPLC analysis of flavonoids in Eupatorium littorale
Published in Journal of the Brazilian Chemical Society (01-01-2001)“…The isolation and identification of eupafolin and hispidulin in the dried leaves of Eupatorium littorale (Asteraceae) are described. A method for the detection…”
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13
New 99m Tc-Labeled Digitoxigenin Derivative for Cancer Cell Identification
Published in ACS omega (24-12-2019)“…In recent years, cardiac glycosides (CGs) have been investigated as potential antiviral and anticancer drugs. Digitoxigenin (DIG) and other CGs have been shown…”
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14
Synthesis and characterisation of a new polycyclic phenazine from 1,4-naphthoquinone
Published in Tetrahedron letters (04-05-2011)“…Bioactive naphthoquinone-derived heterocyclic compounds have been prepared. Herein, we describe the semisynthesis of a new phenazine, through modified Hooker’s…”
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15
Synthesis and trypanocidal activity of 7, 2'-dioxygenated isoflavones and oxypropanolamine derivatives
Published in Journal of the Brazilian Chemical Society (01-11-2005)“…7, 2'-Dihydroxyisoflavone was shown to be active against the bloodstream trypomastigote form of Trypanosoma cruzi, the etiologic agent of Chagas' disease…”
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16
A Complete and Unambiguous 1H and 13C NMR Signals Assignment of para- Naphthoquinones, ortho- and para-Furanonaphthoquinones
Published in Journal of the Brazilian Chemical Society (01-06-2019)“…A complete and unambiguous assignment of 1H and 13C nuclear magnetic resonance (NMR) signals of 29 naphthoquinones is reported on the basis of one- and…”
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17
LAND-USE INTENSIFICATION TRENDS IN THE RIO DE LA PLATA REGION OF SOUTH AMERICA: TOWARD SPECIALIZATION OR RECOUPLING CROP AND LIVESTOCK PRODUCTION
Published in Frontiers of Agricultural Science and Engineering (01-01-2021)“…* Current intensification trends in the Rio de la Plata need urgent re-direction. *Integrated crop-livestock systems reconcile food production with ecosystem…”
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18
Ceratoacantoma: aspectos morfológicos, clínicos e cirúrgicos
Published in Revista Brasileira de cirurgia plástica (2018)Get full text
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PHOSPHORUS FORMS AND ADSORPTION IN A TYPIC QUARTZIPSAMMENT CULTIVATED WITH SUGARCANE HARVESTED WITHOUT BURNING
Published in Caatinga (01-06-2017)“…ABSTRACT The objective of this study was to evaluate the adsorption of phosphorus (P) and changes in the concentrations of organic and inorganic forms of P in…”
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20
ZEÓLITA 4A PARA PURIFICAÇÃO DO GÁS DE ATERRO SANITÁRIO
Published in Química Nova“…The anaerobic decomposition in landfills produces a gas mixture known as landfill biogas. This biogas consists mainly of CH4 and CO2. The CO2 removal can be…”
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