Search Results - "de Souza, Maria A"
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Serotonin and psychostimulant addiction: focus on 5-HT1A-receptors
Published in Progress in neurobiology (01-02-2007)“…Serotonin(1A)-receptors (5-HT(1A)-Rs) are important components of the 5-HT system in the brain. As somatodendritic autoreceptors they control the activity of…”
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2
The in vivo neurochemistry of the brain during general anesthesia
Published in Journal of neurochemistry (01-11-2011)“…J. Neurochem. (2011) 119, 419–446. Anesthesia describes a complex state composed of immobility, amnesia, hypnosis (sleep or loss of consciousness), analgesia,…”
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Neurokinin3 receptor as a target to predict and improve learning and memory in the aged organism
Published in Proceedings of the National Academy of Sciences - PNAS (10-09-2013)“…Impaired learning and memory performance is often found in aging as an early sign of dementia. It is associated with neuronal loss and reduced functioning of…”
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A sphingolipid mechanism for behavioral extinction
Published in Journal of neurochemistry (01-05-2016)“…Reward‐dependent instrumental behavior must continuously be re‐adjusted according to environmental conditions. Failure to adapt to changes in reward…”
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What's conditioned in conditioned place preference?
Published in Trends in pharmacological sciences (Regular ed.) (01-03-2013)“…Conditioned place preference (CPP) is a learned behavior shown in many vertebrates, including humans. CPP occurs when a subject comes to prefer one place more…”
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NK3 receptor agonism reinstates temporal order memory in the hemiparkinsonian rat
Published in Behavioural brain research (15-05-2015)“…•Hemiparkinsonian rats show deficits for temporal order but not novel object memory.•Senktide, a NK3 receptor agonist, reinstates temporal order memory in this…”
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The medial prefrontal cortex - hippocampus circuit that integrates information of object, place and time to construct episodic memory in rodents: Behavioral, anatomical and neurochemical properties
Published in Neuroscience and biobehavioral reviews (01-06-2020)“…•Properties of object exploration tests and neurobiology of time are discussed.•The medial prefrontal cortex (mPFC) and hippocampus involve in object…”
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Potential therapeutic use of herbal extracts in trypanosomiasis
Published in Pathogens and global health (01-01-2014)“…The aim of the present study was to evaluate the effects of crude extracts from Handroanthus impetiginosa, Ageratum conyzoides, and Ruta graveolens on…”
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Chronic corticosterone treatment enhances extinction-induced depression in aged rats
Published in Hormones and behavior (01-11-2016)“…Withdrawal and avoidance behavior are common symptoms of depression and can appear as a consequence of absence of reward, i.e. extinction-induced depression…”
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Disrupted-in-Schizophrenia 1 (DISC1) Overexpression and Juvenile Immune Activation Cause Sex-Specific Schizophrenia-Related Psychopathology in Rats
Published in Frontiers in psychiatry (09-04-2019)“…Synaptic pruning is a critical refinement step during neurodevelopment, and schizophrenia has been associated with overpruning of cortical dendritic spines…”
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11
GABAergic Control of Nigrostriatal and Mesolimbic Dopamine in the Rat Brain
Published in Frontiers in behavioral neuroscience (14-03-2018)“…The present study assessed the effects of the GABA receptor (R) agonist muscimol (MUS), and the GABA R antagonist bicuculline (BIC) on neocortical and…”
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NMDA receptor modulation by D-cycloserine promotes episodic-like memory in mice
Published in Psychopharmacologia (01-09-2007)“…NMDA-R (N-methyl-D-aspartate receptors) have been implicated in synaptic plasticity underlying one-trial learning of event-place associations. In rodents,…”
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Quantitative Proteomics of Synaptosomal Fractions in a Rat Overexpressing Human DISC1 Gene Indicates Profound Synaptic Dysregulation in the Dorsal Striatum
Published in Frontiers in molecular neuroscience (06-02-2018)“…Disrupted-in-schizophrenia 1 (DISC1) is a key protein involved in behavioral processes and various mental disorders, including schizophrenia and major…”
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Active avoidance learning in zebrafish (Danio rerio)—The role of sensory modality and inter-stimulus interval
Published in Behavioural brain research (01-07-2013)“…•Zebrafish can meet the need of a high throughput model in neurobehavioral research.•We further explore the conditions of active avoidance learning in…”
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15
The pharmacology, neuroanatomy and neurogenetics of one-trial object recognition in rodents
Published in Neuroscience and biobehavioral reviews (2007)“…Rats and mice are attracted by novel objects. They readily approach novel objects and explore them with their vibrissae, nose and forepaws. It is assumed that…”
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Intranasal Dopamine Reduces In Vivo [(123)I]FP-CIT Binding to Striatal Dopamine Transporter: Correlation with Behavioral Changes and Evidence for Pavlovian Conditioned Dopamine Response
Published in Frontiers in behavioral neuroscience (22-04-2016)“…Dopamine (DA), which does not cross the blood-brain barrier, has central and behavioral effects when administered via the nasal route. Neither the mechanisms…”
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Decreased methylation of the NK3 receptor coding gene (TACR3) after cocaine-induced place preference in marmoset monkeys
Published in Addiction biology (01-05-2013)“…ABSTRACT Epigenetic processes have been implicated in neuronal plasticity following repeated cocaine application. Here we measured DNA methylation at promoter…”
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The medial prefrontal cortex-lateral entorhinal cortex circuit is essential for episodic-like memory and associative object-recognition
Published in Hippocampus (01-05-2016)“…ABSTRACT The prefrontal cortex directly projects to the lateral entorhinal cortex (LEC), an important substrate for engaging item‐associated information and…”
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Amyloid-β dimers in the absence of plaque pathology impair learning and synaptic plasticity
Published in Brain (London, England : 1878) (01-02-2016)“…Despite amyloid plaques, consisting of insoluble, aggregated amyloid-β peptides, being a defining feature of Alzheimer's disease, their significance has been…”
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Interaction between the medial prefrontal cortex and hippocampal CA1 area is essential for episodic-like memory in rats
Published in Neurobiology of learning and memory (01-05-2017)“…The interplay between medial prefrontal cortex (mPFC) and hippocampus, particularly the hippocampal CA3 area, is critical for episodic memory. To what extent…”
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