Search Results - "de Souza, Izabel Cristina Custódio"
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Short-term effectiveness of transcranial direct current stimulation in the nociceptive behavior of neuropathic pain rats in development
Published in AIMS neuroscience (01-01-2023)“…Neuropathic pain (NP) is caused by a lesion that triggers pain chronification and central sensitization and it can develop in a different manner, dependent of…”
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Analgesic and Sedative Effects of Melatonin in Temporomandibular Disorders: A Double-Blind, Randomized, Parallel-Group, Placebo-Controlled Study
Published in Journal of pain and symptom management (01-09-2013)“…Abstract Context The association between myofascial temporomandibular disorder (TMD) and nonrestorative sleep supports the investigation of therapies that can…”
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Promotion of mitochondrial protection by naringenin in methylglyoxal-treated SH-SY5Y cells: Involvement of the Nrf2/GSH axis
Published in Chemico-biological interactions (01-09-2019)“…Disruption of the mitochondrial function has been associated with redox impairment and triggering of cell death in nucleated human cells, as observed in…”
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The concept of the immune-pineal axis tested in patients undergoing an abdominal hysterectomy
Published in Neuroimmunomodulation (01-01-2013)“…Activation of the immune-pineal axis induces a transient reduction in nocturnal melatonin in the plasma during the proinflammatory phase of an innate immune…”
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Carnosic Acid Induces Anti-Inflammatory Effects in Paraquat-Treated SH-SY5Y Cells Through a Mechanism Involving a Crosstalk Between the Nrf2/HO-1 Axis and NF-κB
Published in Molecular neurobiology (01-01-2018)“…Carnosic acid (CA) is a phenolic diterpene obtained from Rosmarinus officinalis L. and has demonstrated cytoprotective properties in several experimental…”
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Transcranial direct current stimulation effects in the pain threshold and in oxidative stress parameters of neuropathic pain rats
Published in Neuroscience letters (23-04-2023)“…•Pain threshold is reduced in rats with chronic constriction injury.•Neuropathic pain alters redox status in prefrontal cortex and spinal cord of rats.•Bimodal…”
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Mitochondrial Protection and Anti-inflammatory Effects Induced by Emodin in the Human Neuroblastoma SH-SY5Y Cells Exposed to Hydrogen Peroxide: Involvement of the AMPK/Nrf2 Signaling Pathway
Published in Neurochemical research (01-03-2021)“…Emodin (EM; 1,3,8-trihydroxy-6-methylanthracene-9,10-dione; C 15 H 10 O 5 ) is an anthraquinone and exerts cytoprotective effects, as observed in both in vitro…”
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Tanshinone I Attenuates the Effects of a Challenge with H2O2 on the Functions of Tricarboxylic Acid Cycle and Respiratory Chain in SH-SY5Y Cells
Published in Molecular neurobiology (01-12-2017)“…Tanshinone I (T-I; C 18 H 12 O 3 ) is a cytoprotective molecule. T-I has been viewed as an antioxidant and anti-inflammatory agent exerting neuroprotective…”
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The effects of kahweol, a diterpene present in coffee, on the mitochondria of the human neuroblastoma SH-SY5Y cells exposed to hydrogen peroxide
Published in Toxicology in vitro (01-12-2019)“…The oxidative phosphorylation (OXPHOS) system located in the mitochondria is the main source of adenosine triphosphate (ATP) in mammals. The mitochondria are…”
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Resveratrol Regulates the Quiescence-Like Induction of Activated Stellate Cells by Modulating the PPARγ/SIRT1 Ratio
Published in Journal of cellular biochemistry (01-10-2015)“…The activation of hepatic stellate cell (HSC), from a quiescent cell featuring cytoplasmic lipid droplets to a proliferative myofibroblast, plays an important…”
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Static Magnetic Stimulation Induces Changes in the Oxidative Status and Cell Viability Parameters in a Primary Culture Model of Astrocytes
Published in Cell biochemistry and biophysics (01-12-2021)“…Astrocytes play an important role in the central nervous system function and may contribute to brain plasticity response during static magnetic fields (SMF)…”
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Butaphosphan Effects on Glucose Metabolism Involve Insulin Signaling and Depends on Nutritional Plan
Published in Nutrients (22-06-2020)“…Butaphosphan is an organic phosphorus compound used in several species for the prevention of rapid catabolic states, however, the mechanism of action remains…”
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Spinal cord brain-derived neurotrophic factor levels increase after dexamethasone treatment in male rats with chronic inflammation
Published in Neuroimmunomodulation (01-01-2013)“…Dexamethasone is widely used in the therapy of chronic inflammatory diseases for its pain-modulating effects. The objective of this study was to evaluate the…”
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Promotion of Mitochondrial Protection by Emodin in Methylglyoxal-Treated Human Neuroblastoma SH-SY5Y Cells: Involvement of the AMPK/Nrf2/HO-1 Axis
Published in Neurotoxicity research (01-04-2021)“…Mitochondrial dysfunction is part of the mechanism of several human diseases. This negative circumstance may be induced by certain toxicants, as methylglyoxal…”
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Tanshinone I Induces Mitochondrial Protection by a Mechanism Involving the Nrf2/GSH Axis in the Human Neuroblastoma SH-SY5Y Cells Exposed to Methylglyoxal
Published in Neurotoxicity research (01-10-2019)“…Methylglyoxal (MG) is a dicarbonyl molecule exhibiting high reactivity and is a major responsible for glycation in human cells. Accumulation of MG is seen in…”
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Mitochondrial Protection Promoted by the Coffee Diterpene Kahweol in Methylglyoxal-Treated Human Neuroblastoma SH-SY5Y Cells
Published in Neurotoxicity research (2020)“…The coffee diterpene kahweol (KW; C 20 H 26 O 3 ) is a cytoprotective agent exhibiting potent antioxidant actions, as demonstrated in several experimental…”
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Efficacy of melatonin in the treatment of endometriosis: A phase II, randomized, double-blind, placebo-controlled trial
Published in Pain (Amsterdam) (01-06-2013)“…Melatonin reduced pain scores and analgesic use, and improved sleep quality in endometriosis-associated chronic pelvic pain. Melatonin modulates the secretion…”
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Neurobiological effects of transcranial direct current stimulation: a review
Published in Frontiers in psychiatry (2012)“…Transcranial Direct Current Stimulation (tDCS) is a non-invasive brain stimulation technique that is affordable and easy to operate compared to other…”
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Evidence of Anti-Inflammatory Effect of Transcranial Direct Current Stimulation in a CFA-Induced Chronic Inflammatory Pain Model in Wistar Rats
Published in Neuroimmunomodulation (2022)“…Given that chronic inflammatory pain is highly prevalent worldwide, it is important to study new techniques to treat or relieve this type of pain. The present…”
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Carnosic acid depends on glutathione to promote mitochondrial protection in methylglyoxal-exposed SH-SY5Y cells
Published in Metabolic brain disease (01-03-2021)“…Methylglyoxal (MG) is an endogenously produced toxicant that induces mitochondrial dysfunction leading to impaired redox biology homeostasis, bioenergetics…”
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