Search Results - "de Souza, Gustavo H. B"
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In silico approach of secondary metabolites from Brazilian herbal medicines to search for potential drugs against SARS‐CoV‐2
Published in Phytotherapy research (01-08-2021)“…The new severe acute respiratory syndrome coronavirus (SARS‐CoV‐2) recently emerged as a worrying pandemic, with many confirmed cases and deaths globally…”
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Nanostructured Systems Improve the Antimicrobial Potential of the Essential Oil from Cymbopogon densiflorus Leaves
Published in Journal of natural products (Washington, D.C.) (27-12-2019)“…The physicochemical characteristics of nanostructured suspensions are important prerequisites for the success of new drug development. This work aimed to…”
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New Potential Use of Protium spruceanum in Hyperglycemia: α-Glucosidase Inhibition and Protection against Oxidative Stress
Published in Journal of the Brazilian Chemical Society (01-10-2021)“…The high prevalence of diabetes and obesity encourages research for the development of α-glucosidase inhibitors from natural sources. This study evaluated the…”
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Aqueous extract of Baccharis trimera improves redox status and decreases the severity of alcoholic hepatotoxicity
Published in Revista brasileira de farmacognosia (01-11-2017)“…Hepatotoxicity induced by ethanol and the interference of Baccharis trimera aqueous extract (AQ) in this process. When HepG2 cells were incubated with ethanol…”
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Preparation and in vitro evaluation of α and β-amyrins loaded nanoemulsions
Published in Current pharmaceutical biotechnology (01-01-2013)“…The triterpenes α- and β-amyrins display important pharmacological activities. As a result of their high hydrophobia, they present low water solubility and…”
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Trypanocidal activity of (−)-cubebin derivatives against free amastigote forms of Trypanosoma cruzi
Published in Bioorganic & medicinal chemistry letters (17-01-2005)“…The trypanocidal activities of five lignan compounds obtained by partial synthesis from (−)-cubebin ( 2), which was isolated from the seeds of Piper cubeba,…”
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Synthesis and biological activity evaluation of lignan lactones derived from (−)-cubebin
Published in Bioorganic & medicinal chemistry letters (15-02-2005)“…The anti-inflammatory and analgesic activities of three dibenzylbutyrolactone lignans obtained by partial synthesis starting from (−)-cubebin ( 1), which was…”
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