Search Results - "de Souza, Gustavo A."
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Definition of novel cell envelope associated proteins in Triton X-114 extracts of Mycobacterium tuberculosis H37Rv
Published in BMC microbiology (29-04-2010)“…Membrane- and membrane-associated proteins are important for the pathogenicity of bacteria. We have analysed the content of these proteins in virulent…”
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Strong Clonal Relatedness between Serum and Gut IgA despite Different Plasma Cell Origins
Published in Cell reports (Cambridge) (05-09-2017)“…Mucosal antigens induce generation of lamina propria plasma cells (PCs) that secrete dimeric immunoglobulin A (IgA) destined for transport across…”
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Proteomic and Metabolomic Analysis of Azospirillum brasilense ntrC Mutant under High and Low Nitrogen Conditions
Published in Journal of proteome research (03-01-2020)“…Azospirillum brasilense is a diazotrophic microorganism capable of associating with roots of important grasses and cereals, promoting plant growth and…”
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Mechanisms underlying AQP4 accumulation in astrocyte endfeet
Published in Glia (01-11-2015)“…The brain–blood interface holds the key to our understanding of how cerebral blood flow is regulated and how water and solutes are exchanged between blood and…”
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EpitoCore: Mining Conserved Epitope Vaccine Candidates in the Core Proteome of Multiple Bacteria Strains
Published in Frontiers in immunology (05-05-2020)“…In reverse vaccinology approaches, complete proteomes of bacteria are submitted to multiple computational prediction steps in order to filter proteins that are…”
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Proteomic analysis of total cellular proteins of human neutrophils
Published in Proteome science (31-08-2009)“…Neutrophils are the most abundant leukocytes in peripheral blood and represent one of the most important elements of innate immunity. Recent subcellular…”
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Comparison of membrane proteins of Mycobacterium tuberculosis H37Rv and H37Ra strains
Published in BMC microbiology (24-01-2011)“…The potential causes for variation in virulence between distinct M. tuberculosis strains are still not fully known. However, differences in protein expression…”
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High accuracy mass spectrometry analysis as a tool to verify and improve gene annotation using Mycobacterium tuberculosis as an example
Published in BMC genomics (02-07-2008)“…While the genomic annotations of diverse lineages of the Mycobacterium tuberculosis complex are available, divergences between gene prediction methods are…”
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Status of complete proteome analysis by mass spectrometry: SILAC labeled yeast as a model system
Published in Genome biology (19-06-2006)“…Mass spectrometry has become a powerful tool for the analysis of large numbers of proteins in complex samples, enabling much of proteomics. Due to various…”
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The Protein-Protein Interaction Network Reveals a Novel Role of the Signal Transduction Protein PII in the Control of c-di-GMP Homeostasis in Azospirillum brasilense
Published in mSystems (03-11-2020)“…The PII family comprises a group of widely distributed signal transduction proteins ubiquitous in prokaryotes and in the chloroplasts of plants. PII proteins…”
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Renal Amyloidosis Associated With 5 Novel Variants in the Fibrinogen A Alpha Chain Protein
Published in Kidney international reports (01-05-2017)“…Fibrinogen A alpha chain amyloidosis is an autosomal dominant disease associated with mutations in the fibrinogen A alpha chain ( ) gene, and it is the most…”
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Identification of rare alternative splicing events in MS/MS data reveals a significant fraction of alternative translation initiation sites
Published in PeerJ (San Francisco, CA) (13-11-2014)“…Integration of transcriptome data is a crucial step for the identification of rare protein variants in mass-spectrometry (MS) data with important consequences…”
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13
Bacterial proteins with cleaved or uncleaved signal peptides of the general secretory pathway
Published in Journal of proteomics (21-12-2011)“…Correct protein compartmentalization is a key step for molecular function and cell viability, and this is especially true for membrane and externalized…”
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Assessing the Citrullinome in Rheumatoid Arthritis Synovial Fluid with and without Enrichment of Citrullinated Peptides
Published in Journal of proteome research (06-06-2014)“…Protein citrullination is a posttranslational modification that has attracted increased attention, especially for its involvement in rheumatoid arthritis (RA)…”
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A high-throughput pipeline for validation of antibodies
Published in Nature methods (01-11-2018)“…Western blotting (WB) is widely used to test antibody specificity, but the assay has low throughput and precision. Here we used preparative gel electrophoresis…”
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Proteomic analysis of a multi-resistant clinical Escherichia coli isolate of unknown genomic background
Published in Journal of proteomics (16-03-2012)“…Horizontal transfer of gene clusters occurs in Escherichia coli (E. coli), which could lead to evolution of new pathovars and improve survival fitness…”
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Proteomic analyses identify major vault protein as a prognostic biomarker for fatal prostate cancer
Published in Carcinogenesis (New York) (28-05-2021)“…Abstract The demographic shift toward an older population will increase the number of prostate cancer cases. A challenge in the treatment of prostate cancer is…”
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Different binding motifs of the celiac disease-associated HLA molecules DQ2.5, DQ2.2, and DQ7.5 revealed by relative quantitative proteomics of endogenous peptide repertoires
Published in Immunogenetics (New York) (01-02-2015)“…Celiac disease is caused by intolerance to cereal gluten proteins, and HLA-DQ molecules are involved in the disease pathogenesis by presentation of gluten…”
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Characterization of the Small Intestinal Lesion in Celiac Disease by Label-Free Quantitative Mass Spectrometry
Published in The American journal of pathology (01-07-2018)“…Global characterization of tissue proteomes from small amounts of biopsy material has become feasible because of advances in mass spectrometry and…”
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Gluten-specific antibodies of celiac disease gut plasma cells recognize long proteolytic fragments that typically harbor T-cell epitopes
Published in Scientific reports (05-05-2016)“…This study aimed to identify proteolytic fragments of gluten proteins recognized by recombinant IgG1 monoclonal antibodies generated from single IgA plasma…”
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