Search Results - "de Souza, Amancio"
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Plastidial metabolite MEcPP induces a transcriptionally centered stress-response hub via the transcription factor CAMTA3
Published in Proceedings of the National Academy of Sciences - PNAS (02-08-2016)“…The general stress response (GSR) is an evolutionarily conserved rapid and transient transcriptional reprograming of genes central for transducing…”
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2
Functional genomics of RAP proteins and their role in mitoribosome regulation in Plasmodium falciparum
Published in Nature communications (11-03-2022)“…The RAP (RNA-binding domain abundant in Apicomplexans) protein family has been identified in various organisms. Despite expansion of this protein family in…”
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3
Antileshimania, anti- Trypanosoma cruzi and antimicrobial activities of scandenin and 4'-O-methylderrone from Deguelia costata
Published in Natural product research (02-09-2023)“…Scandenin and 4'-O-methylderrone were isolated from the ethanol extract of the roots and dichloromethane extract of the leaves of Deguelia costata (Benth.)…”
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4
Social determinants of pulmonary tuberculosis treatment non-adherence in Rio de Janeiro, Brazil
Published in PloS one (05-01-2018)“…Success in tuberculosis control depends on the implementation of steps that reduce social inequities, allowing the diagnosis and effective treatment of the…”
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5
Retrograde Signals: Integrators of Interorganellar Communication and Orchestrators of Plant Development
Published in Annual review of plant biology (28-04-2017)“…Interorganellar cooperation maintained via exquisitely controlled retrograde-signaling pathways is an evolutionary necessity for maintenance of cellular…”
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6
Comparative genomics of pectinacetylesterases: Insight on function and biology
Published in Plant signaling & behavior (02-09-2015)“…Pectin acetylation influences the gelling ability of this important plant polysaccharide for the food industry. Plant apoplastic pectinacetylesterases (PAEs)…”
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7
Type 2 diabetes-associated genetic variants of FTO, LEPR, PPARg, and TCF7L2 in gestational diabetes in a Brazilian population
Published in Archives of Endocrinology and Metabolism (01-05-2017)“…Gestational diabetes mellitus (GDM) is a metabolic disorder that shares pathophysiologic features with type 2 diabetes mellitus. The aim of this study was to…”
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8
The plastidial retrograde signal methyl erythritol cyclopyrophosphate is a regulator of salicylic acid and jasmonic acid crosstalk
Published in Journal of experimental botany (01-03-2016)“…The exquisite harmony between hormones and their corresponding signaling pathways is central to prioritizing plant responses to simultaneous and/or successive…”
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COBRA-LIKE2, a Member of the Glycosylphosphatidylinositol-Anchored COBRA-LIKE Family, Plays a Role in Cellulose Deposition in Arabidopsis Seed Coat Mucilage Secretory Cells
Published in Plant physiology (Bethesda) (01-03-2015)“…Differentiation of the maternally derived seed coat epidermal cells into mucilage secretory cells is a common adaptation in angiosperms. Recent studies…”
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10
Interplay of the two ancient metabolites auxin and MEcPP regulates adaptive growth
Published in Nature communications (11-06-2018)“…The ancient morphoregulatory hormone auxin dynamically realigns dedicated cellular processes that shape plant growth under prevailing environmental conditions…”
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11
Fruticuline A, a chemically-defined diterpene, exerts antineoplastic effects in vitro and in vivo by multiple mechanisms
Published in Scientific reports (05-10-2020)“…Natural products have been recognized as important bioactive compounds on the basis of their wide biological properties. Here we investigated the antitumor…”
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Blood plasma metabolomics of children and adolescents with sickle cell anaemia treated with hydroxycarbamide: a new tool for uncovering biochemical alterations
Published in British journal of haematology (01-03-2021)“…Summary Sickle cell anaemia (SCA) is a debilitating genetic haemoglobinopathy predominantly affecting the disenfranchised strata of society in Africa and the…”
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The Role of α3β1 Integrin Modulation on Fabry Disease Podocyte Injury and Kidney Impairment
Published in Toxins (01-12-2023)“…Podocyte dysfunction plays a crucial role in renal injury and is identified as a key contributor to proteinuria in Fabry disease (FD), primarily impacting…”
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14
Hydroxyurea treatment is associated with reduced degree of oxidative perturbation in children and adolescents with sickle cell anemia
Published in Scientific reports (04-11-2020)“…Sickle cell anemia (SCA) is the most common inherited hemolytic anemia worldwide. Here, we performed an exploratory study to investigate the systemic oxidative…”
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Initiation of ER Body Formation and Indole Glucosinolate Metabolism by the Plastidial Retrograde Signaling Metabolite, MEcPP
Published in Molecular plant (06-11-2017)“…Plants have evolved tightly regulated signaling networks to respond and adapt to environmental perturbations, but the nature of the signaling hub(s) involved…”
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16
Digital methylation-specific PCR: New applications for liquid biopsy
Published in Biomolecular Concepts (12-02-2024)Get full text
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17
Gene silencing: concepts, applications, and perspectives in woody plants
Published in Scientia agricola (01-12-2007)“…RNA interference, transcriptional gene silencing, virus induced gene silencing, and micro RNAs comprise a series of mechanisms capable of suppressing gene…”
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4-Nitrochalcone as a potential drug in non-clinical breast cancer studies
Published in Chemico-biological interactions (05-01-2024)“…Breast cancer is a high-magnitude public health problem, continually challenging physicians and scientists worldwide in the field of drug therapy…”
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Chemical characterization and antineoplastic effect of oligosaccharides from Cabernet Franc red wine in mammary tumor model in mice
Published in The Journal of nutritional biochemistry (01-03-2023)“…The present study characterized oligosaccharide compounds (Oligo) in Cabernet Franc red wine and investigated its antineoplastic effects against mammary tumor…”
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l-carvone decreases breast cancer cells adhesion, migration, and invasion by suppressing FAK activation
Published in Chemico-biological interactions (01-06-2023)“…Breast cancer is one of the most common types of cancer in the world and current therapeutic strategies present severe drawbacks. l-carvone (CRV), a…”
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