Search Results - "de Sousa, Natália Ferreira"

In Silico Studies of Lamiaceae Diterpenes with Bioinsecticide Potential against Aphis gossypii and Drosophila melanogaster by Rodrigues, Gabriela Cristina Soares, Maia, Mayara Dos Santos, Cavalcanti, Andreza Barbosa Silva, Sousa, Natália Ferreira de, Scotti, Marcus Tullius, Scotti, Luciana

“…The growing demand for agricultural products has led to the misuse/overuse of insecticides; resulting in the use of higher concentrations and the need for ever…”
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Anticancer Activity of Chalcones and Its Derivatives: Review and In Silico Studies by Leite, Fernando Ferreira, de Sousa, Natália Ferreira, de Oliveira, Bruno Hanrry Melo, Duarte, Gabrielly Diniz, Ferreira, Maria Denise Leite, Scotti, Marcus Tullius, Filho, José Maria Barbosa, Rodrigues, Luís Cezar, de Moura, Ricardo Olímpio, Mendonça-Junior, Francisco Jaime Bezerra, Scotti, Luciana

“…Chalcones are direct precursors in the biosynthesis of flavonoids. They have an α,β-unsaturated carbonyl system which gives them broad biological properties…”
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Virtual Screening of Natural Products Database by de Sousa Luis, José Alixandre, Barros, Renata Priscila Costa, de Sousa, Natália Ferreira, Muratov, Eugene, Scotti, Luciana, Scotti, Marcus Tullius

“…Constant research on natural products has generated, over time, a large number of compounds with the potential to be evaluated in several biological tests and…”
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Challenges and Discoveries in Polypharmacology of Neurodegenerative Diseases by Lustoza Rodrigues, Teresa Carolliny Moreira, de Sousa, Natália Ferreira, Dos Santos, Aline Matilde Ferreira, Aires Guimarães, Renan Dantas, Scotti, Marcus Tullius, Scotti, Luciana

“…Neurological disorders are composed of several diseases that affect the central and peripheral nervous system; among these are neurodegenerative diseases,…”
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Multitarget Compounds for Neglected Diseases: A Review by de Sousa, Natália Ferreira, de Sousa, Gabriela Ribeiro, de Lima, Natanael Teles Ramos, de Assis, Edileuza Bezerra, Aragão, Mariana Costa, de Moura, Érika Paiva, Gopalsamy, Rajiv Gandhi, Scotti, Marcus Tullius, Scotti, Luciana

“…Neglected diseases are a group of infectious diseases, many of them parasitic, that mainly affect the poorest populations with limited access to health…”
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Proposition of In silico Pharmacophore Models for Malaria: A Review by de Sousa, Natália Ferreira, de Araújo, Igor Mikael Alves, Rodrigues, Teresa Carolliny Moreira Lustoza, da Silva, Pablo Rayff, de Moura, Jéssica Paiva, Scotti, Marcus Tullius, Scotti, Luciana

“…In the field of medicinal chemistry, the concept of pharmacophore refers to the specific region of a molecule that possesses essential structural and chemical…”
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Seasonality affects the community of endophytic fungi in coconut (Cocos nucifera) crop leaves by Oliveira, Rafael José Vilela de, Sousa, Natalia Mirelly Ferreira de, Pinto Neto, Walter de Paula, Bezerra, José Luiz, Silva, Gladstone Alves da, Cavalcanti, Maria Auxiliadora de Queiroz

“…ABSTRACT The diversity of endophytic fungi in healthy coconut palm leaves (Cocos nucifera) was assessed by analyzing fungal isolates from three coconut…”
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Multi-target Phenylpropanoids Against Epilepsy by Rodrigues, Teresa Carolliny Moreira Lustoza, Dias, Arthur Lins, Dos Santos, Aline Matilde Ferreira, Monteiro, Alex France Messias, Oliveira, Mayara Cecile Nascimento, Pires, Hugo Fernandes Oliveira, de Sousa, Natália Ferreira, Salvadori, Mirian Graciela da Silva Stiebbe, Scotti, Marcus Tullius, Scotti, Luciana

“…Epilepsy is a neurological disease with no defined cause, characterized by recurrent epileptic seizures. These occur due to the dysregulation of excitatory and…”
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Identification of New Targets and the Virtual Screening of Lignans against Alzheimer’s Disease by Scotti, Luciana, Scotti, Marcus Tullius, de Sousa, Natália Ferreira, Rodrigues, Gabriela Cristina Soares, dos Santos Maia, Mayara, Mendonça Junior, Francisco Jaime B.

“…Alzheimer’s disease (AD) is characterized by the progressive disturbance in cognition and affects approximately 36 million people, worldwide. However, the…”
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Inhibition of the morphological transition of Candida spp. by riparins I–IV by Queiroz da Silva, Maria Lucilene, Ferreira de Sousa, Natália, Santos, Antonia Thassya Lucas, Sousa, Gabriela Ribeiro, Fonseca, Victor Juno Alencar, Douglas Melo Coutinho, Henrique, Barbosa Filho, José Maria, Souza Ferrari, Jailton, Scotti, Marcus Tullius, Ribeiro‐Filho, Jaime, Martins de Lima, João Paulo, Rocha, João Batista Teixeira, Bezerra Morais‐Braga, Maria Flaviana

“…Candida spp. is an opportunistic pathogen capable of causing superficial to invasive infections. Morphological transition is one of the main virulence factors…”
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An In Silico Approach to Exploring the Antinociceptive Biological Activities of Linalool and its Metabolites by da Silva, Pablo Rayff, Nunes Pazos, Natalia Diniz, de Andrade, Jéssica Cabral, de Sousa, Natália Ferreira, Oliveira Pires, Hugo Fernandes, de Figueiredo Lima, Jaislânia Lucena, Dias, Arthur Lins, da Silva Stiebbe Salvadori, Mirian Graciela, de Oliveira Golzio, Adriana Maria Fernandes, de Castro, Ricardo Dias, Scotti, Marcus T, Patil, Vaishali M, Bezerra Felipe, Cícero Francisco, de Almeida, Reinaldo Nóbrega, Scotti, Luciana

“…Pain is characterized by the unpleasant sensory and emotional sensation associated with actual or potential tissue damage, whereas nociception refers to the…”
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Recent Studies on Neglected Drug Design by de Sousa, Natália Ferreira, Scotti, Luciana, Rodrigues, Gabriela Cristina Soares, de Moura, Érika Paiva, Costa Barros, Renata Priscila Barros, Sessions, Zoe L, Muratov, Eugene N, Scotti, Marcus Tullius

“…Neglected diseases require special attention when looking for new therapeutic alternatives, as these are diseases of extreme complexity and severity that…”
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Ligand and Structure-based Virtual Screening of Lamiaceae Diterpenes with Potential Activity against a Novel Coronavirus (2019-nCoV) by Rodrigues, Gabriela Cristina Soares, Dos Santos Maia, Mayara, de Menezes, Renata Priscila Barros, Cavalcanti, Andreza Barbosa Silva, de Sousa, Natália Ferreira, de Moura, Érika Paiva, Monteiro, Alex France Messias, Scotti, Luciana, Scotti, Marcus Tullius

“…The emergence of a new coronavirus (CoV), named 2019-nCoV, as an outbreak originated in the city of Wuhan, China, has resulted in the death of more than 3,400…”
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Drug Repurposing Based on Protozoan Proteome: In Vitro Evaluation of In Silico Screened Compounds against Toxoplasma gondii by Cajazeiro, Débora Chaves, Toledo, Paula Pereira Marques, de Sousa, Natália Ferreira, Scotti, Marcus Tullius, Reimão, Juliana Quero

“…is a protozoan that infects up to a third of the world's population. This parasite can cause serious problems, especially if a woman is infected during…”
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Studies of Cytotoxicity Effects, SARS‐CoV‐2 Main Protease Inhibition, and in Silico Interactions of Synthetic Chalcones by Guterres Fernandes, Octavio L., Tizziani, Tiago, Dambrós, Bibiana P., Ferreira de Sousa, Natália, Mansur Pontes, Carime L., Silva, Layzon A. L., Escorteganha Pollo, Luiz A., Assis, Francisco F., Scotti, Marcus T., Scotti, Luciana, Braga, Antonio L., Steindel, Mario, Sandjo, Louis P.

“…SARS‐CoV‐2 main protease (Mpro) plays an essential role in proteolysis cleavage that promotes coronavirus replication. Thus, attenuating the activity of this…”
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The Essential Oil from Conyza bonariensis (L.) Cronquist (Asteraceae) Exerts an In Vitro Antimelanoma Effect by Inducing Apoptosis and Modulating the MAPKs, NF-κB, and PKB/AKT Signaling Pathways by Ferreira, Rafael Carlos, Duarte, Sâmia Sousa, de Sousa, Valgrícia Matias, de Souza, Ramon Ramos Marques, Marques, Karinne Kelly Gadelha, de Abrantes, Renata Albuquerque, do Nascimento, Yuri Mangueira, de Sousa, Natália Ferreira, Scotti, Marcus Tullius, Scotti, Luciana, Tavares, Josean Fechine, Gonçalves, Juan Carlos Ramos, da Silva, Marcelo Sobral, Sobral, Marianna Vieira

“…The characterization and cytotoxicity of the essential oil from (L.) aerial parts (CBEO) were previously conducted. The major compound was ( )-2-lachnophyllum…”
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In Silico and In Vitro Studies of Terpenes from the Fabaceae Family Using the Phenotypic Screening Model against the SARS-CoV-2 Virus by de Sousa, Natália Ferreira, Duarte, Gabrielly Diniz, Moraes, Carolina Borsoi, Barbosa, Cecília Gomes, Martin, Holli-Joi, Muratov, Nail N, Nascimento, Yuri Mangueira do, Scotti, Luciana, de Freitas-Júnior, Lúcio Holanda Gondim, Filho, José Maria Barbosa, Scotti, Marcus Tullius

“…In 2019, the emergence of the seventh known coronavirus to cause severe illness in humans triggered a global effort towards the development of new drugs and…”
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Kaurane-Type Diterpenoids as Potential Inhibitors of Dihydrofolate Reductase-Thymidylate Synthase in New World Leishmania Species by Herrera-Acevedo, Chonny, de Menezes, Renata Priscila Barros, de Sousa, Natália Ferreira, Scotti, Luciana, Scotti, Marcus Tullius, Coy-Barrera, Ericsson

“…The bifunctional enzyme Dihydrofolate reductase-thymidylate synthase (DHFR-TS) plays a crucial role in the survival of the parasite, as folates are essential…”
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Methyleugenol Has an Antidepressant Effect in a Neuroendocrine Model: In Silico and In Vivo Evidence by Oliveira, Mayara Cecile Nascimento, Cavalcante, Ikla Lima, de Araújo, Alana Natalícia, Ferreira dos Santos, Aline Matilde, de Menezes, Renata Priscila Barros, Herrera-Acevedo, Chonny, Ferreira de Sousa, Natália, de Souza Aquino, Jailane, Barbosa-Filho, José Maria, de Castro, Ricardo Dias, Almeida, Reinaldo Nóbrega, Scotti, Luciana, Scotti, Marcus Tullius, Da Silva Stiebbe Salvadori, Mirian Graciela

“…Major depressive disorder is a severe mood disorder characterized by different emotions and feelings. This study investigated the antidepressant activity of…”
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The Compound (E) -2-Cyano- N ,3-diphenylacrylamide (JMPR-01): A Potential Drug for Treatment of Inflammatory Diseases by da Silva, Pablo Rayff, do Espírito Santo, Renan Fernandes, Melo, Camila de Oliveira, Pachú Cavalcante, Fábio Emanuel, Costa, Thássia Borges, Barbosa, Yasmim Vilarim, E Silva, Yvnni M S de Medeiros, de Sousa, Natália Ferreira, Villarreal, Cristiane Flora, de Moura, Ricardo Olímpio, Dos Santos, Vanda Lucia

“…The compound -2-cyano- ,3-diphenylacrylamide (JMPR-01) was structurally developed using bioisosteric modifications of a hybrid prototype as formed from…”
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