Search Results - "de Sousa, María Elisa"
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Impact of magnetite iron oxide nanoparticles on wheat (Triticum aestivum L.) development: Evaluation of oxidative damage
Published in Environmental and experimental botany (01-11-2016)“…•A rise in iron content and a superparamagnetic signal were found in treated roots.•Fe3O4 nanoparticles were detected in the root epidermal cell walls but not…”
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COVID-19: Integrating the Complexity of Systemic and Pulmonary Immunopathology to Identify Biomarkers for Different Outcomes
Published in Frontiers in immunology (29-01-2021)“…In the last few months, the coronavirus disease 2019 (COVID-19) pandemic has affected millions of people worldwide and has provoked an exceptional effort from…”
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Patents in therapeutic recombinant protein production using mammalian cells
Published in Recent patents on biotechnology (2014)“…The industrial production of recombinant proteins preferentially requires the generation of stable cell lines expressing proteins in a quick, relatively…”
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Role of crotoxin in coagulation: novel insights into anticoagulant mechanisms and impairment of inflammation-induced coagulation
Published in The journal of venomous animals and toxins including tropical diseases (2020)“…Snake venom phospholipases A (svPLA ) are biologically active toxins, capable of triggering and modulating a wide range of biological functions. Among the…”
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SK-HEP cells and lentiviral vector for production of human recombinant factor VIII
Published in Biotechnology letters (01-08-2012)“…Hemophilia A is caused by a deficiency in coagulation factor VIII. Recombinant factor VIII can be used as an alternative although it is unavailable for most…”
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Purification Method for Recombinant hG-CSF by Affinity Chromatography
Published in Methods in molecular biology (Clifton, N.J.) (2018)“…The human granulocytic colony-stimulating factor (hG-CSF) acts mainly by promoting the maturation of granulocytes and stimulating their phagocytic and…”
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Evaluation of the extraction process of the essential oil from Cymbopogon schoenanthus with pressurized carbon dioxide
Published in Brazilian archives of biology and technology (01-06-2005)“…The objective of this work was to study the essential oil extraction process of Cymbopogon schoenanthus Spreg with pressured CO2, and to compare the results…”
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Human Cells as Platform to Produce Gamma-Carboxylated Proteins
Published in Methods in molecular biology (Clifton, N.J.) (2018)“…The gamma-carboxylated proteins belong to a family of proteins that depend on vitamin K for normal biosynthesis. The major representative gamma-carboxylated…”
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Induced Pluripotent Stem Cell for the Study and Treatment of Sickle Cell Anemia
Published in Stem cells international (01-01-2017)“…Sickle cell anemia (SCA) is a monogenic disease of high mortality, affecting millions of people worldwide. There is no broad, effective, and safe definitive…”
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Human cell lines: A promising alternative for recombinant FIX production
Published in Protein expression and purification (01-05-2016)“…Factor IX (FIX) is a vitamin K-dependent protein, and it has become a valuable pharmaceutical in the Hemophilia B treatment. We evaluated the potential of…”
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SUPERCRITICAL EXTRACTION OF LINSEED OIL: ECONOMICAL VIABILITY AND MODELING EXTRACTION CURVES
Published in Chemical engineering communications (01-01-2013)“…The aim of the present study was to use supercritical technology to recover linseed oil (Linum usitatissimum L.) using carbon dioxide (alone or modified with…”
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Murine leukemia virus-derived retroviral vector has differential integration patterns in human cell lines used to produce recombinant factor VIII
Published in Revista brasileira de hematologia e hemoterapia (01-05-2014)“…Nowadays recombinant factor VIII is produced in murine cells including in Chinese hamster ovary (CHO) and baby hamster kidney cells (BHK). Previous studies,…”
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Integration pattern of HIV-1 based lentiviral vector carrying recombinant coagulation factor VIII in Sk-Hep and 293T cells
Published in Biotechnology letters (01-01-2011)“…293T and Sk-Hep-1 cells were transduced with a replication-defective self-inactivating HIV-1 derived vector carrying FVIII cDNA. The genomic DNA was sequenced…”
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Electrochemical aptasensor for NS1 detection: Towards a fast dengue biosensor
Published in Talanta (Oxford) (01-10-2021)“…Dengue is one of the most commonly neglected tropical diseases transmitted by Aedes aegypti infected with Dengue virus. This virus belongs to the gender…”
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Recombinant Expression of Complex Proteins in Human Cell Lines
Published in Methods in molecular biology (Clifton, N.J.) (2022)“…Coagulation factors, as factor VII, VIII, and IX, are complex proteins which are very difficult to express. Blood coagulation factor IX is a vitamin…”
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Ten years of iPSC: clinical potential and advances in vitro hematopoietic differentiation
Published in Cell biology and toxicology (01-06-2017)“…Ten years have passed since the first publication announcing the generation of induced pluripotent stem cells (iPSCs). Issues related to ethics, immune…”
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Approaches for recombinant human factor IX production in serum-free suspension cultures
Published in Biotechnology letters (01-03-2016)“…OBJECTIVE: To establish a serum-free suspension process for production of recombinant human factor IX (rhFIX) based on the human cell line HEK 293T by…”
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Síntese, caracterização e avaliação do poder antimicrobiano do nanocompósito Ag/TiO2
Published in Journal of Engineering and Exact Sciences (12-12-2020)“…Nas últimas décadas houve um aumento no interesse em estudos no campo da nanotecnologia, e isso se deve às diversas vantagens e aplicações que os nanomateriais…”
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Clonagem e expressão da glicoproteína transmembrana do vírus linfotrópico de células T humanas em sistema procarioto Cloning and expression of the transmembranic glycoprotein from human T cell lymphotropic virus in a prokaryotic system
Published in Revista da Sociedade Brasileira de Medicina Tropical (01-06-2007)“…O HTLV-1 é o vírus causador da leucemia/linfoma de célula T no adulto e de uma desordem neurológica conhecida por mielopatia associada ao HTLV ou paraparesia…”
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Clonagem e expressão da glicoproteína transmembrana do vírus linfotrópico de células T humanas em sistema procarioto
Published in Revista da Sociedade Brasileira de Medicina Tropical (01-06-2007)“…O HTLV-1 é o vírus causador da leucemia/linfoma de célula T no adulto e de uma desordem neurológica conhecida por mielopatia associada ao HTLV ou paraparesia…”
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