Search Results - "de Sousa, Lorena"

Inhibition of Leishmania amazonensis arginase by fucogalactan isolated from Agrocybe aegerita mushroom by Motoshima, Renan Akio, Rosa, Tainara da F., Mendes, Léia da C., Silva, Estefânia Viana da, Viana, Sthefany R.F., Amaral, Bruno Sérgio do, de Souza, Dulce H.F., Lião, Luciano M., Corradi da Silva, Maria de Lourdes, de Sousa, Lorena R.F., Carbonero, Elaine R.

“…•A fucogalactan (FG-Aa) was purified from the medicinal mushroom Agrocybe aegerita.•The fucogalactan was highly branched by non-reducing ends of α-Fucp.•FG-Aa…”
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Phosphoenolpyruvate carboxykinase from T. cruzi magnetic beads affinity-based screening assays on crude plant extracts from Brazilian Cerrado by do Amaral, Bruno S., da Silva, Larissa R.G., Valverde, Alessandra L., de Sousa, Lorena R.F., Severino, Richele P., de Souza, Dulce H.F., Cass, Quezia B.

“…[Display omitted] •Cerrado Brazilian plants ethanolic extract as natural products library.•High specificity affinity-based assay for PEPCK.•Eleven ligands…”
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Natural products as inhibitors of recombinant cathepsin L of Leishmania mexicana by de Sousa, Lorena R.F., Wu, Hongmei, Nebo, Liliane, Fernandes, João B., da Silva, Maria F. das G.F., Kiefer, Werner, Schirmeister, Tanja, Vieira, Paulo C.

“…•Natural products were screened against L. mexicana cathepsin L (rCPB2.8).•A triterpene and some flavonoids are inhibitors of rCPB2.8.•The inhibitors of…”
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Flavonoids as noncompetitive inhibitors of Dengue virus NS2B-NS3 protease: Inhibition kinetics and docking studies by de Sousa, Lorena Ramos Freitas, Wu, Hongmei, Nebo, Liliane, Fernandes, João Batista, da Silva, Maria Fátima das Graças Fernandes, Kiefer, Werner, Kanitz, Manuel, Bodem, Jochen, Diederich, Wibke E., Schirmeister, Tanja, Vieira, Paulo Cezar

“…[Display omitted] NS2B-NS3 is a serine protease of the Dengue virus considered a key target in the search for new antiviral drugs. In this study flavonoids…”
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COVID-19 gastrointestinal manifestations: a systematic review by Silva, Filipe Antônio França da, Brito, Breno Bittencourt de, Santos, Maria Luísa Cordeiro, Marques, Hanna Santos, Silva Júnior, Ronaldo Teixeira da, Carvalho, Lorena Sousa de, Vieira, Elise Santos, Oliveira, Márcio Vasconcelos, Melo, Fabrício Freire de

“…The pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has greatly challenged public health worldwide. A growing number…”
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Using molecular networking and docking to explore arginase inhibitors among Drimys brasiliensis chemical constituents by Mendes, Léia da C., Dantas, Thais B. Vieira, Severino, Richele P., da Silva, Larissa Ramos G., de Souza, Dulce H. F., Cass, Quezia B., Ramalho, Suelem D., Vieira, Paulo C., de Souza, Guilherme E., Guido, Rafael V. C., Urschel, Marie-Kathrin, Kersten, Christian, de Sousa, Lorena R. F.

“…Arginase is a potential target of drugs against Leishmania spp. Natural products can be a source of arginase inhibitors. This study has investigated whether…”
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Chemical Prospection of Qualea grandiflora Mart. Fruit and Stem Extracts and Their in vitro and in vivo Antiplasmodial Activity by Gonçalves Neto, Geraldo, da Costa, Romário, Zanini, Camila, Aguiar, Anna Caroline, de Souza, Juliana, de Souza, Guilherme, Severino, Richele, Cass, Quezia, Cruz, Fábio, Oliva, Glaucius, Guido, Rafael, de Sousa, Lorena

“…Qualea grandiflora Mart. (“pau-terra”) is a medicinal plant symbolic from Cerrado biome. Qualea species reportedly have antiparasitic properties, but their…”
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Genetic diversity and population structure of sugarcane (Saccharum spp.) accessions by means of microsatellites markers by Zeni Neto, Hugo, Borsuk, Luiz Gustavo da Mata, Santos, Luiz Renato Frederico dos, Angeli, Henrique Sanches, Berton, Guilherme Souza, Sousa, Lorena Lopes de

“…The success of sugarcane (Saccharum spp.) breeding programs depends on the choice of productive parent lines that have a high industrial yield and are…”
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NEW DEGRADED QUINONE DITERPENOID FROM THE STEMS OF Byrsonima coccolobifolia Kunth. (Malpighiaceae) by Sousa, Lorena, Santos, Marcos, Severino, Vanessa, Severino, Richele, Vieira, Paulo

“…A chemical investigation of two specimens of Byrsonima coccolobifolia collected in the southeast cerrado and from central Brazil was performed. A new degraded…”
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Metabolites from Marine Sponges and Their Potential to Treat Malarial Protozoan Parasites Infection: A Systematic Review by Aguiar, Anna Caroline Campos, Parisi, Julia Risso, Granito, Renata Neves, de Sousa, Lorena Ramos Freitas, Renno, Ana Cláudia Muniz, Gazarini, Marcos Leoni

“…Malaria is an infectious disease caused by protozoan parasites of the genus through the bite of female Anopheles mosquitoes, affecting 228 million people and…”
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Dissolution test for oral suspension: an overview about use and importance by Soares, Thaís dos Santos Paulino, Souza, Jacqueline de, Rosa, Lorena de Sousa, Marques-Marinho, Flávia Dias

“…Abstract This work aims to ascertain the comprehensiveness of dissolution tests for oral suspensions registered in Brazil and the USA. After consulting…”
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Triterpenoids as Novel Natural Inhibitors of Human Cathepsin L by Ramalho, Suelem D., De Sousa, Lorena R. F., Nebo, Liliane, Maganhi, Stella H., Caracelli, Ignez, Zukerman-Schpector, Julio, Lima, Maria Inês S., Alves, Marcio F. M., Da Silva, M. Fátima das G. F., Fernandes, João B., Vieira, Paulo C.

“…Cathepsins L (catL) and B play an important role in tumor progression and have been considered promising therapeutic targets in the development of novel…”
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Equilibrium solubility study to determine fexofenadine hydrochloride BCS class and challenges in establishing conditions for dissolution profiles applied to suspension by Rosa, Lorena de Sousa, Marques-Marinho, Flávia Dias, Braga, Silmara Leôncio, Souza, Jacqueline de

“…The aim of this work was to perform solubility studies for fexofenadine hydrochloride and establish dissolution conditions for this drug in oral suspension…”
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Evaluation of flavonols and derivatives as human cathepsin B inhibitor by Ramalho, Suelem D., de Sousa, Lorena R. F., Burger, Marcela C. M., Lima, Maria Inês S., da Silva, M. Fátima das G. F., Fernandes, João B., Vieira, Paulo C.

“…Cathepsin B (catB) is a cysteine protease involved in tumour progression and represents a potential therapeutic target in cancer. Among the 15 evaluated…”
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Perspectives for the use of plant extracts to control the cattle tick Rhipicephalus (Boophilus) microplus by Borges, Lígia Miranda Ferreira, Sousa, Lorena Alessandra Dias de, Barbosa, Carolina da Silva

“…The evolution of resistance of Rhipicephalus (Boophilus) microplus to synthetic acaricides has given rise to the need for new scientific investigations on…”
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Soil Quality Influences Efficacy of Melia azedarach (Sapindales: Meliaceae), Fruit Extracts Against Rhipicephalus (Boophilus) microplus (Acari: Ixodidae) by Sousa, Lorena A. D. De, Costa, Deomar P. Da, Ferri, Pedro H, Showler, Allan T, Borges, Lígia M. F

“…Hexane extract of chinaberry, Melia azedarach L., unripe fruits obtained from different municipalities of Goiás State, Brazil, were evaluated on the southern…”
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Fiber source and xylanase on performance, egg quality, and gastrointestinal tract of laying hens by Sousa, Lorena Salim de, Carvalho, Thiago Soares Martins, Nogueira, Flávia Aparecida, Saldanha, Mariana Masseo, Vaz, Diego Pereira, Bertechini, Antônio Gilberto, Baião, Nelson Carneiro, Lara, Leonardo José Camargos

“…ABSTRACT The objective of this study was to ascertain the influence of different dietary fiber sources and the usage of xylanase on diet of commercial layers…”
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Ovary histology and quantification of hemolymph proteins of Rhipicephalus (Boophilus) microplus treated with Melia azedarach by de Sousa, Lorena Alessandra Dias, Rocha, Thiago Lopes, Sabóia-Morais, Simone Maria Teixeira, Borges, Lígia Miranda Ferreira

“…This study aimed to analyze ovary histology and quantify total protein in the hemolymph of Rhipicephalus (Boophilus) microplus females treated with hexane…”
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Leukocytoclastic Vasculitis as an Extraintestinal Manifestation of Crohn’s Disease by Rocha, Thiara Barcelos, Garate, Ana Lorena Sousa de Vasconcelos, Beraldo, Rodrigo Fedatto, Lanças, Sean Hideo Shirata, Leite, Fábio Vicente, Quera, Rodrigo, Barros, Jaqueline Ribeiro, Baima, Julio Pinheiro, Saad-Hossne, Rogerio, Sassaki, Ligia Yukie

“…Abstract Cutaneous involvement is one of the most common extraintestinal manifestations of inflammatory bowel disease (IBD). More commonly, pyoderma…”
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Leishmanicidal Galloylquinic Acids are Noncompetitive Inhibitors of Arginase by Sousa, Lorena R. F. de, Ramalho, Suelem D., Fernandes, João B., Silva, Maria Fátima das G. F. da, Iemma, Mônica R. da C., Corrêa, Caroindes J., Souza, Dulce H. F. de, Lima, Maria I. S., Vieira, Paulo C.

“…Leishmanicidal galloylquinic acids were isolated from the ethyl acetate extract of Byrsonima coccolobifolia. These phenols and gallic acid showed to be a new…”
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